Additional file 1: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Bram P. Prins (Creator)
Timothy J. Mead (Creator)
Jennifer A Brody (Creator)
Gardar Sveinbjornsson (Contributor)
Ioanna Ntalla (Creator)
Nathan A. Bihlmeyer (Creator)
Marten van den Berg (Contributor)
Jette Bork-Jensen (Creator)
Stefania Cappellani (Creator)
Stefan Van Duijvenboden (Contributor)
Nikolai T. Klena (Creator)
George C. Gabriel (Creator)
Xiaoqin Liu (Contributor)
Cagri Gulec (Contributor)
Niels Grarup (Creator)
Jeffrey Haessler (Creator)
Leanne M Hall (Creator)
Annamaria Iorio (Creator)
Aaron Isaacs (Creator)
Ruifang Li-Gao (Contributor)
Honghuang Lin (Creator)
Ching-Ti Liu (Contributor)
Leo-Pekka Lyytikäinen (Contributor)
Jonathan Marten (Creator)
Hao Mei (University of Mississippi Medical Center) (Creator)
Martina Müller-Nurasyid (Contributor)
Michele Orini (Creator)
Sandosh Padmanabhan (Contributor)
Farid Radmanesh (Creator)
Julia Ramirez (Creator)
Antonietta Robino (Creator)
Molly Schwartz (Creator)
Jessica van Setten (Contributor)
Albert V Smith (Creator)
Niek Verweij (Creator)
Helen R. Warren (Creator)
Stefan Weiss (Creator)
Alvaro Alonso (Creator)
David O. Arnar (Creator)
Michiel L. Bots (University Medical Center Utrecht) (Creator)
Rudolf A de Boer (Contributor)
Anna F Dominiczak (Creator)
Mark Eijgelsheim (Creator)
Patrick T. Ellinor (Massachusetts General Hospital) (Creator)
Xiuqing Guo (Contributor)
Stephan B. Felix (Creator)
Tamara B. Harris (Creator)
Caroline Hayward (Creator)
Susan R. Heckbert (University of Washington) (Creator)
Paul L. Huang (Massachusetts General Hospital) (Creator)
J.W. Jukema (Leiden University Medical Center - LUMC, Netherlands Heart Institute, Durrer Center for Cardiogenetic Research) (Contributor)
Mika Kähönen (Contributor)
Jan A Kors (Creator)
Pier D. Lambiase (Department of Applied Health Research, St Bartholomew's Hospital) (Creator)
Lenore J. Launer (Creator)
Man Li (Creator)
Allan Linneberg (Kobenhavns Universitet, Rigshospitalet, Research Centre for Prevention and Health, Capital Region of Denmark) (Creator)
Christopher P Nelson (Creator)
Oluf Pedersen (Slagelse Hospital) (Creator)
Marco Perez (Department of Surgery) (Creator)
Annette Peters (Creator)
Ozren Polasek (Creator)
Bruce M Psaty (Creator)
Olli Raitakari (Creator)
Kenneth M Rice (Creator)
Jerome I. Rotter (Creator)
Moritz F Sinner (Creator)
Elsayed Z. Soliman (Contributor)
Tim D. Spector (Creator)
Konstantin Strauch (Creator)
Unnur Thorsteinsdottir (Creator)
Andrew Tinker (Barts and The London School of Medicine and Dentistry, School of Mathematical Sciences) (Creator)
Stella Trompet (Creator)
André G. Uitterlinden (Contributor)
Ilonca Vaartjes (University Medical Center Utrecht) (Creator)
Peter van der Meer (University of Groningen, University Medical Center Groningen) (Contributor)
Uwe Völker (Contributor)
Henry Völzke (Contributor)
Melanie Waldenberger (Creator)
James G. Wilson (Creator)
Zhijun Xie (Zhejiang Chinese Medical University) (Contributor)
Folkert W. Asselbergs (Creator)
Marcus Dörr (Contributor)
Cornelia M van Duijn (Contributor)
Paolo Gasparini (Creator)
Daniel F Gudbjartsson (Creator)
Vilmundur Gudnason (Creator)
Torben Hansen (University of Copenhagen, Faculty of Health Sciences) (Creator)
Stefan Kääb (Contributor)
Jørgen K. Kanters (Slagelse Hospital) (Contributor)
Charles Kooperberg (Creator)
T. Lehtimäki (Contributor)
Henry J. Lin (Creator)
Steven A. Lubitz (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center) (Creator)
Dennis O. Mook-Kanamori (Creator)
Francesco J. Conti (UCL Great Ormond Street Institute of Child Health) (Creator)
Christopher H. Newton-Cheh (Harvard Medical School, Massachusetts Institute of Technology) (Creator)
Jonathan Rosand (Creator)
Igor Rudan (Creator)
Nilesh J. Samani (Contributor)
Gianfranco Sinagra (Ospedali Riuniti di Ancona) (Creator)
Blair H Smith (Creator)
Hilma Holm (Creator)
Bruno H Stricker (Creator)
Sheila Ulivi (Creator)
Nona Sotoodehnia (Creator)
Suneel S. Apte (Cleveland Clinic Foundation) (Contributor)
Pim van der Harst (Contributor)
Kari Stefansson (Creator)
Patricia B Munroe (Creator)
Dan E Arking (Creator)
Cecilia W. Lo (University of Pittsburgh Medical School) (Creator)
Yalda Jamshidi (Contributor)

Clinical Medicine

Dataset

Description

Table S1. Cohort characteristics. Table S2. Single SNP meta-analyses. Table S3. Sex-stratified analyses. Table S4. SKAT analyses. Table S5. T1-burden analyses. Table S6. ADAMTS6 variant details. Table S7. Cardiac phenotype distribution in Adamts6 mutant mice. (XLSX 475 kb)

Date made available	17 Jul 2018

Field of science, Statistics Finland

3121 Internal medicine
318 Medical biotechnology

DOI
10.6084/m9.figshare.6823781.v1

1 Article

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R., & 15 othersLin, H., Liu, C-T., Lyytikäinen, L-P., Marten, J., Hao, M., Mueller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., Set, V., Kähönen, M. & Lehtimäki, T., 2018, In: Genome biology. 19, 1, p. 8 87.
Research output: Contribution to journal › Article › Scientific › peer-review

16 Citations (Scopus)

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Prins, B. P. (Creator), Mead, T. J. (Creator), Brody, J. A. (Creator), Sveinbjornsson, G. (Contributor), Ntalla, I. (Creator), Bihlmeyer, N. A. (Creator), van den Berg, M. (Contributor), Bork-Jensen, J. (Creator), Cappellani, S. (Creator), Van Duijvenboden, S. (Contributor), Klena, N. T. (Creator), Gabriel, G. C. (Creator), Liu, X. (Contributor), Gulec, C. (Contributor), Grarup, N. (Creator), Haessler, J. (Creator), Hall, L. M. (Creator), Iorio, A. (Creator), Isaacs, A. (Creator), Li-Gao, R. (Contributor), Lin, H. (Creator), Liu, C. (Contributor), Lyytikäinen, L. (Contributor), Marten, J. (Creator), Mei, H. (Creator), Müller-Nurasyid, M. (Contributor), Orini, M. (Creator), Padmanabhan, S. (Contributor), Radmanesh, F. (Creator), Ramirez, J. (Creator), Robino, A. (Creator), Schwartz, M. (Creator), van Setten, J. (Contributor), Smith, A. V. (Creator), Verweij, N. (Creator), Warren, H. R. (Creator), Weiss, S. (Creator), Alonso, A. (Creator), Arnar, D. O. (Creator), Bots, M. L. (Creator), de Boer, R. A. (Contributor), Dominiczak, A. F. (Creator), Eijgelsheim, M. (Creator), Ellinor, P. T. (Creator), Guo, X. (Contributor), Felix, S. B. (Creator), Harris, T. B. (Creator), Hayward, C. (Creator), Heckbert, S. R. (Creator), Huang, P. L. (Creator), Jukema, J. W. (Contributor), Kähönen, M. (Contributor), Kors, J. A. (Creator), Lambiase, P. D. (Creator), Launer, L. J. (Creator), Li, M. (Creator), Linneberg, A. (Creator), Nelson, C. P. (Creator), Pedersen, O. (Creator), Perez, M. (Creator), Peters, A. (Creator), Polasek, O. (Creator), Psaty, B. M. (Creator), Raitakari, O. T. (Creator), Rice, K. M. (Creator), Rotter, J. I. (Creator), Sinner, M. F. (Creator), Soliman, E. Z. (Contributor), Spector, T. D. (Creator), Strauch, K. (Creator), Thorsteinsdottir, U. (Creator), Tinker, A. (Creator), Trompet, S. (Creator), Uitterlinden, A. (Contributor), Vaartjes, I. (Creator), van der Meer, P. (Contributor), Völker, U. (Contributor), Völzke, H. (Contributor), Waldenberger, M. (Creator), Wilson, J. G. (Creator), Xie, Z. (Contributor), Asselbergs, F. W. (Creator), Dörr, M. (Contributor), van Duijn, C. M. (Contributor), Gasparini, P. (Creator), Gudbjartsson, D. F. (Creator), Gudnason, V. (Creator), Hansen, T. (Creator), Kääb, S. (Contributor), Kanters, J. K. (Contributor), Kooperberg, C. (Creator), Lehtimäki, T. (Contributor), Lin, H. J. (Creator), Lubitz, S. A. (Creator), Mook-Kanamori, D. O. (Creator), Conti, F. J. (Creator), Newton-Cheh, C. H. (Creator), Rosand, J. (Creator), Rudan, I. (Creator), Samani, N. J. (Contributor), Sinagra, G. (Creator), Smith, B. H. (Creator), Holm, H. (Creator), Stricker, B. H. (Creator), Ulivi, S. (Creator), Sotoodehnia, N. (Creator), Apte, S. S. (Contributor), van der Harst, P. (Contributor), Stefansson, K. (Creator), Munroe, P. B. (Creator), Arking, D. E. (Creator), Lo, C. W. (Creator), Jamshidi, Y. (Contributor) (17 Jul 2018). Additional file 1: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS610.6084/m9.figshare.6823781.v1

Additional file 1: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Description

Field of science, Statistics Finland

DOI

Research output

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Cite this