Children's and Women's health, Diagnostic Medicine, Psychiatry

2025

A_2A receptor antagonist 4-(2-((6-Amino-9-ethyl-8-(furan-2-yl)-9H-purin-2-yl)amino)ethyl)phenol, a promising adenosine derivative for glioblastoma treatment

Murugesan, A., Smirnov, A., Alonso, A. V., Buccioni, M., Cui, C., Dal Ben, D., Francucci, B., Lambertucci, C., Marucci, G., Volpini, R., Konda Mani, S., Devanesan, S., AlSalhi, M. S., Yli-Harja, O., Spinaci, A. & Kandhavelu, M., 1 Apr 2025, In: European Journal of Pharmaceutical Sciences. 207, 107039.

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Broadening the Phenotype Spectrum of MECP2 Variants in Men

Lötjönen, J., Kurra, V., Laivuori, H. & Bjelogrlić, N., Feb 2025, In: Molecular Genetics and Genomic Medicine. 13, 2, 8 p., e70056.

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Clinical features and treatment of stroke-like episodes in mitochondrial disease: a cohort-based study

Mickelsson, N., Hirvonen, J. & Martikainen, M. H., Jan 2025, In: JOURNAL OF NEUROLOGY. 272, 1, 11 p., 47.

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Consensus outcomes between health professionals and parents for oral corticosteroids in treating preschool wheeze: A multi-national survey and nominal group technique study

Lee, B., Turner, S. W., Hine, J., McMurray, A., Roland, D., Borland, M. L., Csonka, P., Grigg, J., Guilbert, T. W., Jartti, T., Oommen, A., Lewis, S. & Cunningham, S., 2025, (E-pub ahead of print) In: ARCHIVES OF DISEASE IN CHILDHOOD. 7 p.

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Determination of steroid reference intervals in a pregnancy population

Lahti-Pulkkinen, M., Räikkönen, K., Basiukajc, A., Lee, P., Denham, S. G., Simpson, J. P., Villa, P., Hämäläinen, E., Laivuori, H., Kajantie, E., Heinonen, K., Girchenko, P., Reynolds, R. M. & Homer, N. Z., Apr 2025, In: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 248, 16 p., 106691.

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Development of Cell-Assembled Human Endomysial-Type Biomatrix Substrate for the Detection of Celiac Disease Autoantibodies

Korponay-Szabó, I. R., Király, R., Gyimesi, J. & Mäki, M., 2025, In: International Journal of Molecular Sciences. 26, 3, 18 p., 1012.

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Development of the PRECIOUS Short-Form (PRECIOUS-SF) quality of care measure for children with serious illnesses

Ang, F. J. L., Cheung, Y. B., Gandhi, M., Malhotra, R., Ostbye, T., Malhotra, C., Chow, C. C. T., Chong, P. H., Amin, Z., Tan, T. S. Z. & Finkelstein, E., 24 Jan 2025, In: Journal of Patient-Reported Outcomes. 9, 1, 8 p., 12.

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Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure

Kusterer, M., Lahnalampi, M., Voutilainen, M., Brand, A., Pennisi, S., Norona, J., Gentile, G., Herzog, H., Greve, G., Lübbert, M., Sipola, M., Kaartinen, E., Sankowski, R., Prinz, M., Killmer, S., Lago, M. S., Bengsch, B., Cysar, S. R., Aumann, K. & Werner, M. & 4 others, Duyster, J., Lohi, O., Heinäniemi, M. & Duque-Afonso, J., Feb 2025, In: HemaSphere. 9, 2, 18 p., e70071.

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Effect of arthroscopic partial meniscectomy on structural degeneration of the knee: A 5-year MRI-based follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial

Sillanpää, N., Iivanainen, M., Turkiewicz, A., Sihvonen, R., Paavola, M., Taimela, S., Järvinen, T. L. N. & Englund, M., 2025, In: Osteoarthritis and Cartilage. 33, 2, p. 276-282 7 p.

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Effect of nutritional supplementation with lipid-based therapeutic food on body composition of non-severely malnourished African children aged 6-59 months hospitalized with severe pneumonia

Nalwanga, D., Musiime, V., Kiguli, S., Olupot-Olupot, P., Alaroker, F., Opoka, R., Tagoola, A., Mnjala, H., Mogaka, C., Nabawanuka, E., Giallongo, E., Karamagi, C., Briend, A. & Maitland, K., Apr 2025, In: JOURNAL OF TROPICAL PEDIATRICS. 71, 2, 11 p., fmaf010.

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Efficacy of subsequent therapies in patients with advanced ovarian cancer who relapse after first-line olaparib maintenance: results of the PAOLA-1/ENGOT-ov25 trial

PAOLA-1/ENGOT-ov25 investigators, Harter, P., Marth, C., Mouret-Reynier, M. A., Cropet, C., Lorusso, D., Guerra-Alía, E. M., Matsumoto, T., Vergote, I., Colombo, N., Mäenpää, J., Lebreton, C., de Gregorio, N., Mosconi, A. M., Rubio-Pérez, M. J., Bourgeois, H., Fasching, P. A., Cecere, S. C., Hardy-Bessard, A. C. & Denschlag, D. & 11 others, de Percin, S., Hanker, L., Favier, L., Bauerschlag, D., Desauw, C., Hillemanns, P., Largillier, R., Sehouli, J., Grenier, J., Pujade-Lauraine, E. & Ray-Coquard, I., 2025, In: ANNALS OF ONCOLOGY. 36, 2, p. 185-196 12 p.

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Gluten-free diet during pregnancy and pregnancy outcome: A retrospective cohort study

Reijonen, J. K., Tihtonen, K. M. H., Luukkaala, T. H. & Uotila, J. T., 2025, (E-pub ahead of print) In: INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS. 7 p.

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Identifying risk factors for vomiting during diarrhea: A secondary analysis of a randomized trial of zinc supplementation

Edwards, J. G., Dhingra, P., Liu, E., Dhingra, U., Dutta, A., Sudfeld, C. R., Deb, S., Somji, S., Aboud, S., Kisenge, R., Sazawal, S., Ashorn, P., Simon, J., Manji, K. P. & Duggan, C. P., 2025, (E-pub ahead of print) In: Journal of Pediatric Gastroenterology and Nutrition. 13 p.

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Interplay of atherosclerosis and medial degeneration in human ascending aorta

Huhta, A., Paavonen, T., Mennander, A. & Kholová, I., Jan 2025, In: Cardiovascular Pathology. 74, 11 p., 107702.

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Intimal sarcoma of the lower pulmonary vein diagnosed by Endobronchial Ultrasound-Guided Fine-Needle Aspiration (EBUS-FNA): A case report and comprehensive literature review

Elmas, H., Kholová, I., Meierling, S. & Welker, L., 2025, In: Cardiovascular Pathology. 76, 6 p., 107717.

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Intracranial Arteriovenous Malformations During Pregnancy and Puerperium: A Retrospective Nationwide Population-Based Cohort Study

Pohjola, A., Vest, T., Verho, L., Aarnio, K., Rantanen, K., Laivuori, H., Gissler, M., Laakso, A., Niemelä, M. & Ijäs, P., 1 Feb 2025, In: Neurosurgery. 96, 2, p. 346-355 10 p.

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Intrauterine Contraction Monitoring in Chorioamnionitis: A Secondary, Blinded Analysis of a Randomised Controlled Trial Cohort

Juhantalo, M., Hautakangas, T., Palomäki, O. & Uotila, J., 2025, (E-pub ahead of print) In: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 10 p.

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Investigating male factors and their relationships with reproductive health outcomes: a case-control study protocol for Towards Optimal Fertility, Fathering, and Fatherhood studY (TOFFFY) in Singapore

Ku, C. W., Pek, J. W., Cheung, Y. B., Tharmalingam Durgahshree, M. D., Chan, M., Lee, Y. H., Godfrey, K., Yap, F., Chan, J. K. Y. & Loy, S. L., 15 Jan 2025, In: BMJ Open. 15, 1, 8 p., e088143.

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Maternal Antenatal Depression Is Associated With Metabolic Alterations That Predict Birth Outcomes and Child Neurodevelopment and Mental Health

Girchenko, P., Lahti-Pulkkinen, M., Laivuori, H., Kajantie, E. & Räikkönen, K., Feb 2025, In: BIOLOGICAL PSYCHIATRY. 97, 3, p. 269-278

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Metabolic profiles of meconium in preeclamptic and normotensive pregnancies

Toivonen, E., Sikkinen, J., Salonen, A., Kärkkäinen, O., Koistinen, V., Klåvus, A., Meuronen, T., Heini, T., Maltseva, A., Niku, M., Jääskeläinen, T. & Laivuori, H., 25 Jan 2025, In: Metabolomics. 21, 1, p. 21 1 p.

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Parental depression and emotional feeding practices are associated with a tendency towards overeating in preadolescents

Sarkkola, C., Leppänen, M. H., Eloranta, A. M., Räisänen, L., Männistö, S. & Viljakainen, H., Jan 2025, In: Frontiers in Nutrition. 11, 1497509.

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Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder

Lähteenvuo, M., Tiihonen, J., Solismaa, A., Tanskanen, A., Mittendorfer-Rutz, E. & Taipale, H., Jan 2025, In: JAMA psychiatry. 82, 1, p. 94-98 5 p.

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Reverse Time-to-Death as Time-Scale in Time-to-Event Analysis for Studies of Advanced Illness and Palliative Care

Cheung, Y. B., Ma, X., Chaudhry, I., Liu, N., Zhuang, Q., Yang, G. M., Malhotra, C. & Finkelstein, E. A., 10 Feb 2025, In: STATISTICS IN MEDICINE. 44, 3-4, e10338.

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Searching for a serial killer on a hospital ward

Karhunen, P. J., Krohn, R., Oksala, A., Louhelainen, A. M., Kavanto, A. & Auvinen, A., Feb 2025, In: FORENSIC SCIENCE INTERNATIONAL. 367, 112337.

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The oncolytic adenovirus TILT-123 with pembrolizumab in platinum resistant or refractory ovarian cancer: the phase 1a PROTA trial

Block, M. S., Clubb, J. H. A., Mäenpää, J., Pakola, S., Quixabeira, D. C. A., Kudling, T., Jirovec, E., Haybout, L., van der Heijden, M., Zahraoui, S., Grönberg-Vähä-Koskela, S., Raatikainen, S., Arias, V., Basnet, S., Ojala, N., Pellinen, T., Hemmes, A., Välimäki, K., Pasanen, A. & Alanko, T. & 14 others, Adamo, D., Ramadan, S., Sormunen, J., Kononen, J., Cohen, J. W., Chisamore, M. J., Goldfinch, J., Sorsa, S., Havunen, R., Kistler, C., Kalervo, A., Cervera-Carrascon, V., dos Santos, J. M. & Hemminki, A., Dec 2025, In: Nature Communications. 16, 1, 1381.

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Tracking and Transition Probability of Blood Pressure From Childhood to Midadulthood

Meng, Y., Sharman, J. E., Iiskala, F., Wu, F., Juonala, M., Pahkala, K., Rovio, S. P., Fraser, B. J., Kelly, R. K., Hutri, N., Kähönen, M., Laitinen, T., Jula, A., Viikari, J. S. A., Raitakari, O. T. & Magnussen, C. G., Jan 2025, In: JAMA Pediatrics. 179, 1, p. 34-45 12 p.

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Unsupervised clustering reveals noncanonical myeloid cell subsets in the brain tumor microenvironment

Hermelo, I., Virtanen, T., Salonen, I., Nätkin, R., Keitaanniemi, S., Tiihonen, A. M., Lehtipuro, S., Kummola, L., Raulamo, E., Nordfors, K., Haapasalo, H., Rauhala, M., Kesseli, J., Nykter, M., Haapasalo, J. & Rautajoki, K., 3 Jan 2025, In: Cancer Immunology, Immunotherapy. 74, 2, 63.

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Venous thromboembolism in children with Hodgkin lymphoma: A population-based study in Sweden, Finland, and Denmark

Giertz, M., Aarnivala, H., Michelsen, S. W., Björklund, C., Grönroos, M., Hjalgrim, L. L., Huttunen, P., Niinimäki, R., Pöyhönen, T., Raittinen, P., Ranta, S., Svahn, J. E., Törnudd, L., Englund, A. & Harila, A., Apr 2025, In: THROMBOSIS RESEARCH. 248, 109287.

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X-ray microtomography imaging enables accurate visualization and quantification of the small-intestinal villi microvasculature: – celiac disease as a model

Reunamo, A., Hannula, M., Virta, J., Kurppa, K., Lindfors, K. & Hyttinen, J., Mar 2025, In: MICROVASCULAR RESEARCH. 158, 104782.

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2024

Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors

Pekkarinen, M., Nordfors, K., Uusi-Mäkelä, J., Kytölä, V., Hartewig, A., Huhtala, L., Rauhala, M., Urhonen, H., Häyrynen, S., Afyounian, E., Yli-Harja, O., Zhang, W., Helen, P., Lohi, O., Haapasalo, H., Haapasalo, J., Nykter, M., Kesseli, J. & Rautajoki, K. J., 2024, In: Life science alliance. 7, 6, 18 p., e202302088.

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Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence

Haapala, E. A., Leppänen, M. H., Lee, E., Savonen, K., Laukkanen, J. A., Kähönen, M., Brage, S. & Lakka, T. A., 19 Mar 2024, In: Journal of the American Heart Association. 13, 6, 13 p., e031837.

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Accumulation of Lewy-Related Pathology Starts in Middle Age: The Tampere Sudden Death Study

Kok, E. H., Paetau, A., Martiskainen, M., Lyytikäinen, L. P., Lehtimäki, T., Karhunen, P. & Myllykangas, L., May 2024, In: ANNALS OF NEUROLOGY. 95, 5, p. 843-848 6 p.

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Accuracy of Intra-Axial Brain Tumor Characterization in the Emergency MRI Reports: A Retrospective Human Performance Benchmarking Pilot Study

Sirén, A., Turkia, E., Nyman, M. & Hirvonen, J., Aug 2024, In: Diagnostics. 14, 16, 1791.

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A cohort study in family triads: impact of gut microbiota composition and early life exposures on intestinal resistome during the first two years of life

Jokela, R., Pärnänen, K. M. M., Ponsero, A. J., Lahti, L., Kolho, K.-L., de Vos, W. M. & Salonen, A., 2024, In: GUT MICROBES. 16, 1, 2383746.

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Acute recanalization therapy for ischemic stroke during pregnancy and puerperium

Richardt, A., Aarnio, K., Korhonen, A., Rantanen, K., Verho, L., Curtze, S., Laivuori, H., Gissler, M., Tikkanen, M. & Ijäs, P., 2024, In: JOURNAL OF NEUROLOGY. 271, 7, p. 4046-4056 11 p.

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Adalimumabin ja etanerseptin hinnat laskivat Viroa hitaammin

Katunin, E., Linden, K. & Rutanen, J., 2024, In: Suomen Lääkärilehti. 79, 17-18

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Adaptation of interpersonal counselling for adolescent (IPC-A) for Finnish student welfare services - retrospective evaluation by using the framework for reporting adaptations and modifications-enhanced (FRAME)

Seilo, N., Mämmi, K. & Linnaranta, O., 2024, In: PSYCHIATRIA FENNICA. 55, p. 48-63 16 p.

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Adolescent alcohol and cannabis use and early adulthood educational attainment in the 1986 Northern Finland birth cohort study

Levola, J., Alakokkare, A. E., Denissoff, A., Mustonen, A., Miettunen, J. & Niemelä, S., Jan 2024, In: BMC Public Health. 24, 1, 10 p., 255.

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A dual fluorescence protein expression system detects cell cycle dependent protein noise

Murugesan, A., Alshagrawi, R. A., Thiyagarajan, R. & Kandhavelu, M., Apr 2024, In: International Journal of Biological Macromolecules. 263, 7 p., 130262.

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A genome-wide association meta-analysis of all-cause and vascular dementia

The Mega Vascular Cognitive Impairment and Dementia (MEGAVCID) consortium, Fongang, B., Sargurupremraj, M., Jian, X., Mishra, A., Damotte, V., de Rojas, I., Skrobot, O., Bis, J. C., Fan, K. H., Jacobsen, E., Li, G. H. Y., Yang, J., Alessandra, B., Alessandra, L., Hilal, S., Chong, J. R., Chai, Y. L., Knol, M. J. & Concas, M. P. & 31 others, Giorgia, G., Riaz, M., Yu, C., Guojonsson, A., Lacaze, P., Naj, A. C., Gireud-Goss, M., Wadop, Y. N., Soumare, A., Bouteloup, V., Gudnason, V., Battista, P., Santin, A., Spedicati, B., Sardone, R., Launer, L., Bressler, J., Gottesman, R. F., Grand, Q. L., Caro, I., Roshchupkin, G. V., Leonard, H. L., Yang, C., Bartz, T. M., Bordes, C., Ridker, P. M., Geerlings, M. I., Gasca, N. C., Manichaikul, A., Nalls, M. A. & Karhunen, P., Sept 2024, In: Alzheimer's and Dementia. 20, 9, p. 5973-5995 23 p.

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AI is a viable alternative to high throughput screening: a 318-target study

The Atomwise AIMS Program, Wallach, I., Bernard, D., Nguyen, K., Ho, G., Morrison, A., Stecula, A., Rosnik, A., O’Sullivan, A. M., Davtyan, A., Samudio, B., Thomas, B., Worley, B., Butler, B., Laggner, C., Thayer, D., Moharreri, E., Friedland, G., Truong, H. & van den Bedem, H. & 31 others, Ng, H. L., Stafford, K., Sarangapani, K., Giesler, K., Ngo, L., Mysinger, M., Ahmed, M., Anthis, N. J., Henriksen, N., Gniewek, P., Eckert, S., de Oliveira, S., Suterwala, S., PrasadPrasad, S. V. K., Shek, S., Contreras, S., Hare, S., Palazzo, T., O’Brien, T. E., Van Grack, T., Williams, T., Chern, T. R., Kenyon, V., Lee, A. H., Cann, A. B., Bergman, B., Anderson, B. M., Virtanen, A., Musta, K., Silvennoinen, O. & Haikarainen, T., 2024, In: Scientific Reports. 14, 1, 7526.

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Aikuisille tarvitaan kansallinen ADHD-suositus

Jääskeläinen, E., Koski, A., Tani, P., Korkeila, J., Kampman, O., Karlsson, H., Saarni, S., Sassi, P., Faninger-Lund, H., Väyrynen, T., Halt, A.-H. & Vataja, R., May 2024, In: Suomen Lääkärilehti. 79, 22, p. 916-917

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All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996-2019: a register study

Ruuska, S. M., Tuisku, K., Holttinen, T. & Kaltiala, R., 17 Feb 2024, In: BMJ mental health. 27, 6 p., e300940.

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A microbiota-directed complementary food intervention in 12-18-month-old Bangladeshi children improves linear growth

Mostafa, I., Hibberd, M. C., Hartman, S. J., Hafizur Rahman, M. H., Mahfuz, M., Hasan, S. M. T., Ashorn, P., Barratt, M. J., Ahmed, T. & Gordon, J. I., Jun 2024, In: Ebiomedicine. 104, p. 105166

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Analysis of early childhood intestinal microbial dynamics in a continuous-flow bioreactor

DIABIMMUNE Study Group, Granato, A., Renwick, S., Yau, C., Kong, T., Daigneault, M. C., Knip, M., Allen-Vercoe, E. & Danska, J. S., Dec 2024, In: Microbiome. 12, 1, 255.

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An analysis of the diagnoses and costs of pediatric emergency care visits: a single center study

Kauppala, A., Heikkilä, P. & Palmu, S., 2024, In: BMC Health Services Research. 24, 7 p., 251.

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Antibiootit.fi-verkkosivustolta tukea lasten yleisimpien infektioiden hoitoon

Csonka, P. & Kuitunen, I., 2024, In: Duodecim. 140, 11, p. 917-919 3 p.

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Antipsychotic medications and sleep problems in patients with schizophrenia

Cederlöf, E., Holm, M., Taipale, H., Tiihonen, J., Tanskanen, A., Lähteenvuo, M., Lahdensuo, K., Kampman, O., Wegelius, A., Isometsä, E., Kieseppä, T., Palotie, A., Suvisaari, J., Paunio, T. & SUPER-Finland study, May 2024, In: SCHIZOPHRENIA RESEARCH. 267, p. 230-238 9 p.

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Aortic elastic fiber degeneration during acute type a aortic dissection and reverse aortic remodeling

Chen, T., Kholova, I., Paavonen, T. & Mennander, A., Feb 2024, In: JOURNAL OF CARDIOTHORACIC SURGERY. 19, 9 p., 80.

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A retrospective analysis of iv ketamine outcome on hospitalizations in an unselected psychiatric sample

Sandström, K., Kampman, O. & Asellus, P., 2024, (E-pub ahead of print) In: ACTA NEUROPSYCHIATRICA.

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Children's and Women's health, Diagnostic Medicine, Psychiatry

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