Department of Clinical Chemistry

Research output

Research output per year 1994 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2012 2013 2014 2015 2016 2017 2018 2019 2020 2025

• 3120 Article
• 224 Chapter
• 89 Doctoral thesis
• 77 Review Article
• 105 More
  • 72 Conference contribution
  • 11 Comment/debate
  • 7 Anthology
  • 6 Editorial
  • 4 Letter
  • 3 Commissioned report
  • 1 Book
  • 1 Software

Research output per year

Research output per year

Search results

• 2023

  Effects of Beta Blocker Therapy on RR Interval Correlations During Exercise

  Pukkila, T., Molkkari, M., Kanniainen, M., Hernesniemi, J., Nikus, K., Lyytikäinen, L.-P., Lehtimäki, T., Viik, J., Kähönen, M. & Räsänen, E., 2023, 2023 Computing in Cardiology (CinC). Computing in Cardiology, 4 p. (Computing in Cardiology; vol. 50).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

  Open Access

  File

  • During Exercise 100%
  • RR Interval 100%
  • Beta-blockers 100%
  • Interval Correlation 100%
  • Beta-blocker Therapy 100%
  33 Downloads (Pure)
• 2022

  Metabolomics in the prediction of prodromal stages of carotid artery disease using a hybrid ML algorithm

  Pezoulas, V., Mishra, P. P., Raitakari, O. T., Kahonen, M., Lehtimaki, T., Fotiadis, D. I. & Sakellarios, A. I., 2022, 022 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI): BHI-BSN 2022 Symposium Proceedings. IEEE, p. 1-4 (IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

  • Intima-media Thickness 100%
  • Metabolomics 100%
  • Prodromal Stage 100%
  • Hybrid ML Model 100%
  • Carotid Artery Disease 100%
  2 Citations (Scopus)
• 2021

  A hybrid data harmonization workflow using word embeddings for the interlinking of heterogeneous cross-domain clinical data structures

  Pezoulas, V. C., Sakellarios, A., Kleber, M., Bosch, J. A., Laan, S. W. V. D., Lamers, F., Lehtimäki, T., März, W. & Fotiadis, D. I., 2021, 2021 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

  • Clinical Data 100%
  • Cross-domain 100%
  • Data Harmonization 100%
  • Word Embedding 100%
  • Hybrid Data 100%
  2 Citations (Scopus)
• 2014

  CCND1 is a miR-193b target in prostate cancer

  Tuppurainen, K., Rauhala, H., Scaravilli, M., Vessella, R. & Visakorpi, T., 2014, Unknown. Vol. 74. p. 5205 (Cancer Research; vol. 74, no. S19).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2007

  Upregulated level of TRAIL and soluble Fas ligand in IFN-beta treated relapsing-remitting multiple sclerosis patients

  Rinta, S., Kuusisto, H., Raunio, M. & Elovaara, I., 2007, 23rd Congress of the European Committee for the Treatment and Research in Multiple Sclerosis (ECTRIMS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2006

  Aberrant DMPK expression in DM1 and DM2 patients

  Raheem, O., Holmlund-Hampf, J., Suominen, T., Vihola, A., Haapasalo, H., Krahe, R. & Udd, B., 2006, Unknown. Vol. 16. p. 670-671 (Neuromuscular Disorders; vol. 16, no. 9-10).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Alternative oxidase, a potential therapy for mitochondrial diseases

  Dassa, E., GAI, H., Dufour, E., Larsson, N., Jacobs, H. & Rustin, P., 2006, 14th European Bioenergetics Conference. Vol. 34. p. 534-535 (Biochimica Et Biophysica Acta- Bioenergetics; vol. 34, no. s S).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3a Synthesis in Activated Macrophages

  Jalonen, U., Nieminen, R., Vuolteenaho, K., Kankaanranta, H. & Moilanen, E., 2006, XVth World Congress of Pharmacology. Vol. 27. p. 286-286 (Acta Pharmacologica Sinica; vol. 27, no. s 1).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2004

  Chitosane membranes in wound healing.

  Mäki, T., Laine, A., Muhonen, J., Enislidis, G., Ylikomi, T., Linqvist, C., Kellomäki, M. & Suuronen, R., 2004, Unknown. Vol. 32. p. 262-263 (Journal of Cranio-Maxillofacial Surgery; vol. 32).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Machine vision systems in automatic biological analysis in testing new materials for fixation and tissue engineering

  Korpinen, J., Ylikomi, T. & Suuronen, R., 2004, Unknown. Vol. 32. p. 264 (Journal of Cranio-Maxillofacial Surgery; vol. 32).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2003

  Comparison of the Quick and Owren prothrombin time methods for the INR system

  Horsti, J., 2003, XXXVI Nordic Coagulation congress. p. 21

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• EQA in classival vytogenetics - the labquality experoemce

  Simola, K., 2003, Unknown. Vol. 46. p. 82 (Annales de Genetigue; vol. 46, no. 2).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2002

  A novel low-penetrance locus for familial glioma at 15q23-q26.3

  Paunu, N., Lahermo, P., Onkamo, P., Ollikainen, V., Rantala, I., Helen, P., Simola, K. & Haapasalo, H., 2002, 7th European Congress of Neuropathology NEUROPATHOLOGY 2002. p. P O-07

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

  49 Citations (Scopus)

• Impaired renal function after treatment of brain tumors diagnosed in childhood

  Pietilä, S., Ala-Houhala, M., Lenko, H., Harmoinen, A., Turjanmaa, V., Haapasalo, H. & Mäkipernaa, A., 2002, SIOP XXXIV Meeting. Official Journal of SIOP, Wiley-Liss, Vol. 39. p. 351 (Medical And Pediatric Oncology; vol. 39, no. 4).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Renal failure and hypertension are mainly associated with cisplatin treatment in brain tumor pateints diagnosed in childhood

  Pietilä, S., Ala-Houhala, M., Lenko, H., Harmoinen, A., Turjanmaa, V., Haapasalo, H. & Mäkipernaa, A., 2002, 10th International Symposium on Paediatric Neuro-Oncology. ISPNO, p. 33

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
• 2000

  Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in j774 macrophages

  Korhonen, R., Kankaanranta, H., Lahti, A., Lähde, M., Knowles, R. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Calcium signalling regulates inducible nitric oxide synthesis in macrophages

  Korhonen, R., Kankaanranta, H., Lahti, A., Moilanen, E. & Lähde, M., 2000, Biology of Nitric Oxide Part 7. Proceeedings of the 6th International Meeting on the Biology of Nitric Oxide. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 166

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

• Can eosinophils be programmed to die in asthma?

  Kankaanranta, H., Zhang, X. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Effects of TNFalfa-antagonists on nitric oxide production in human articular cartilage

  Vuolteenaho, K., Moilanen, T. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Effects of TNSalfa-antagonists on nitric oxide production in human articular cartilage

  Vuolteenaho, K., Moilanen, T. & Moilanen, E., 2000, Unknown. Vol. 8. (Osteoarthritis And Cartilage; vol. 8, no. B:S61).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Estradiol valerate-levonorgestrel therapy decreases 18:1 trans fatty acid content in plasma phospholipids

  Lilja, M., Salmi, M., Solakivi, T., Teisala, K., Punnonen, R. & Jokela, H., 2000, Atherosclerosis. XIIth International Symposium on Atherosclerosis. Elsevier, p. 204

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Exhaled nitric oxide as a marker of asthmatic inflammation

  Lehtimäki, L., Saarelainen, S., Kankaanranta, H., Turjanmaa, V. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Exhaled nitric oxide in asthmatics and healthy volunteers

  Lehtimäki, L., Saarelainen, S., Kankaanranta, H., Turjanmaa, V. & Moilanen, E., 2000, Biology of Nitric Oxide Part 7. Proceedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm, Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 91

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Exhaled nitric oxide in patients with asthma before and after inhaled fluticasone treatment

  Lehtimäki, L., Kankaanranta, H., Saarelainen, S., Turjanmaa, V., Koivula, T. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Exhaled NO in patients with asthma before and after inhaled fluticasone treatment

  Lehtimäki, L., Kankaanranta, H., Saarelainen, S., Turjanmaa, V., Koivula, T. & Moilanen, E., 2000, World Congress on Lung Health and 10th ERS Annual Congress. Vol. 16. p. A2386 (European Respiratory Journal. Supplement; vol. 16, no. S31).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Extracellular signal regulated kinase is involved in inducible nitric oxide synthase upregulation in macrophages

  Lahti, A., Kankaanranta, H. & Moilanen, E., 2000, Biology of Nitric Oxide Part 7. Proceeedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm, Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 168

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Functional 5A/6A polymorphism in human stromelysin-1 gene is in age-dependent relation to autopsy-verified calcified coronary lesions

  Pöllänen, P., Karhunen, P., Mikkelsson, J., Mattila, K., Syrjäkoski, K., Nikkari, S., Koivula, T. & Lehtimäki, T., 2000, Atherosclerosis XII. Stemme, S. & Olsson, A. (eds.). Amsterdam: Elsevier, p. 212

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Increased serum MMP-9 concentrations in patients with angiographically assessed coronary artery disease

  Kalela, A., Koivu, T., Kanervisto, J., Sillanaukee, P., Lehtimäki, T. & Nikkari, S., 2000, XII Atherosclerosis. Stemme, S. & Olsson, A. (eds.). Amsterdam: Elsevier, Vol. 151. p. 195 (Atherosclerosis; vol. 151, no. 1).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Induction of nitric oxide production in human T84 intestinal epithelial cells by bacterial lipopolysaccharide

  Lähde, M., Korhonen, R., Moilanen, E. & Hämäläinen, M., 2000, Biology of Nitric Oxide Part 7. Proceeedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm, Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 180

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Inheritance of human longevity: Distribution of cytokine, mt DNA and certain other allelic polymorphisms in 90+ population and their impact on functional status and survival

  Hervonen, A., Jylhä, M., Wang, X., Karhunen, P., Kunnas, T. & Hurme, M., 2000, 15th Nordic Gerontological Congress. American Federation for Aging Research, p. 58

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Inhibition by cyclosporine a of nitric oxide production and inos expression

  Lähde, M. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• LPS-induced no production in human T84 intestinal epithelial cells. Characterization and pharmacological control. Nitric Oxide - Basic Research and Clinical Applications

  Lähde, M. & Moilanen, E., 2000, Ettore Majorana Foundation and Centre for Scientific Culture.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• LSP-induced no production in human T84 intestinal epithelial cells. Characterization and pharmacological control

  Lähde, M. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Markers of nitric oxide and peroxynitrite production in arthritis

  Holm, P., Lähde, M., Leirisalo-Repo, M., Tuomiranta, T., Moilanen, T., Kankaanranta, H., Peltomaa, R. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Markers of nitric oxide production in rheumatoid arthritis

  Holm, P., Kankaanranta, H., Lähde, M., Moilanen, E. & Hämäläinen, M., 2000, Biology of Nitric Oxide Part 7. Proceeedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm, Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 96

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Nitric oxide and peroxynitrite in arthritis

  Holm, P., Lähde, M., Leirisalo-Repo, M., Tuomiranta, T. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Nitric oxide inhibits neutrophil adhesion to human entothelial cells

  Kosonen, O., Kankaanranta, H. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• P38 203580 has a biphasic effects on LPS induced NO production in mouse macrophages and in human epithelial cells

  Lahti, A., Kankaanranta, H. & Moilanen, E., 2000, IMT-TAUH research day 2000.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• P38 inhibitor SB203580 has biphasic effect on LPS induced NO production in mouse macrophages and in human epithelial cells

  Lahti, A., Kankaanranta, H. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Paraoxonase gene coding high and low active alloenzymes modulates coronary function in young men

  Malin, R., Solakivi, T., Lehtimäki, T., Knuuti, J., Janatuinen, T., Laaksonen, R., Vesalainen, R., Nuutila, P., Jokela, H., Laakso, J. & Jaakkola, O., 2000, Atherosclerosis. XIIth International Symposium on Atherosclerosis. Elsevier, Vol. 151. p. 208 (Atherosclerosis; vol. 151).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Paraoxonase gene polymorphism and coronary reactivity in young healthy males

  Malin, R., Solakivi, T., Lehtimäki, T., Knuuti, J., Janatuinen, T., Laaksonen, R., Vesalainen, R., Nuutila, P., Jokela, H., Laakso, J. & Jaakkola, O., 2000, IMT/TAUH Research Days.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Regulation of eosinophil apoptosis by nitric oxide

  Zhang, X., Moilanen, E., Lindsay, M., Lähde, M., Giembycz, M., Barnes, P., Kankaanranta, H. & Hämäläinen, M., 2000, Biology of Nitric Oxide Part 7. Proceeedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm, Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 207

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Regulation of nitric oxide synthesis in human articular cartilage

  Vuolteenaho, K., Moilanen, T. & Moilanen, E., 2000, Biology of Nitric Oxide Part 7. Proceedings of the 6th International Meeting on the Biology of Nitric Oxide, Stockholm,Sweden, September 1999. Moncada, S., Gustafsson, L., Wiklund, N. & Higgs, E. (eds.). London: Portland Press Ltd, p. 87

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Regulation of nitric oxide synthesis in human osteoarthritic articular cartilage

  Moilanen, T., Vuolteenaho, K. & Moilanen, E., 2000, Unknown. Vol. 8. (Osteoarthritis And Cartilage; vol. 8, no. B:S61).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Regulation of nitric oxide synthesis in human osteoarthritic cartilage

  Moilanen, T., Vuolteenaho, K. & Moilanen, E., 2000, Unknown. p. 114 (Scandinavian Journal of Rheumatology. Supplement).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Resistance to topoisomerase IIalfa inhibitor chremotherapy is acquired through topoIIalfa deletions and mutations

  Kauraniemi, P., Wessel, I., Järvinen, T., Jensen, P., Schestad, M. & Isola, J., 2000, The First Euroconference on Quantitative Molecular Cytogenetics. p. 39-

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review
• 1998

  A quality system for the urinalysis laboratory

  Kouri, T., Hongisto, T., Malminiemi, O. & Mulari, I., 1998, 23rd IAMLT Congress.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Comparison of two new homogenous assays for HDL-cholesterol: Wako immunoinhibition method and Roche direct method.

  Jokela, H., Harmoinen, A. & Solakivi, T., 1998, Unknown. Vol. 55. p. 88 (Scandinavian Journal of Clinical And Laboratory Investigation. Supplement; vol. 55, no. S228).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Correlation between Neurological Dysfunction, Volumes of Plaques and Atrophy in Multiple Sclerosis Using a Semiautomatic MRI Segmentation Method

  Dastidar, P., Heinonen, T., Peltola, J., Ukkonen, M., Lehtimäki, T., Erilä, T. & Elovaara, I., 1998, American Academy of Neurology. 50th Annual Meeting. April 25-May 2, 1998, Minneapolis, MN, USA, A Supplement to Neurology. p. s. A107-A108

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific

• Effect of allopurinol treatment on free radicals in coronary sinus blood in CABG patients measured by plasma total peroxyl radical scavenging capacity and electron spin resonance

  Tarkka, M., Vuolle, M., Kaukinen, S., Holm, P., Eloranta, J., Kaukinen, U., Sisto, T. & Kataja, J., 1998, The 47th Annual Meeting of the Scandinavian Association for Thoracic Surgery and the 18th Annual Meeting of the Scandinavian Society for Extracorporeal Technology. p. 52

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific