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• Crystal structure of JAK2 JH2 in complex with Bemcentinib

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Contributor), Hubbard, S. R. (Contributor) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8BA3/pdb

  Dataset

• Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis

  Bouras, E. (Creator), Karhunen, V. (Creator), Gill, D. (Creator), Huang, J. (Creator), Haycock, P. C. (Creator), Gunter, M. J. (Creator), Johansson, M. (Creator), Brennan, P. (Creator), Key, T. (Creator), Lewis, S. J. (Creator), Martin, R. M. (Creator), Murphy, N. (Creator), Platz, E. A. (Creator), Travis, R. (Creator), Yarmolinsky, J. (Creator), Zuber, V. (Creator), Martin, P. (Creator), Katsoulis, M. (Creator), Freisling, H. (Creator), Nøst, T. H. (Creator), Schulze, M. B. (Creator), Dossus, L. (Creator), Hung, R. J. (Creator), Amos, C. I. (Creator), Ahola-Olli, A. (Creator), Palaniswamy, S. (Creator), Männikkö, M. (Creator), Auvinen, J. (Creator), Herzig, K.-H. (Creator), Keinänen-Kiukaanniemi, S. (Creator), Lehtimäki, T. (Creator), Salomaa, V. (Creator), Raitakari, O. (Creator), Salmi, M. (Creator), Jalkanen, S. (Creator), Jarvelin, M.-R. (Creator), Dehghan, A. (Creator) & Tsilidis, K. K. (Creator), figshare, 11 Jan 2022

  DOI: 10.6084/m9.figshare.c.5786587.v1

  Dataset

• Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with HTSA3

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Contributor), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8EX2/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with HTS-A3

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8B8U/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with Reversine

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8BAK/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with Z902-A1

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8BA2/pdb

  Dataset

• Bacterial avidins are a widely distributed protein family in Actinobacteria, Proteobacteria and Bacteroidetes

  Laitinen, O. (Creator), Tanja, K. (Creator), Kukkurainen, S. (Creator), Nurminen, A. (Creator), Sinkkonen, A. (Creator) & Hytönen, V. P. (Creator), figshare, 10 Apr 2021

  DOI: 10.6084/m9.figshare.c.5371198.v1

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with JNJ-7706621

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8B99/pdb

  Dataset

• Crystal structure of JAK2 JH2 in complex with Z902-A3

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8B9H/pdb

  Dataset

• Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

  McCartney, D. L. (Creator), Min, J. L. (Creator), Richmond, R. C. (Creator), Lu, A. T. (Creator), Sobczyk, M. K. (Creator), Davies, G. (Creator), Broer, L. (Creator), Guo, X. (Creator), Jeong, A. (Creator), Jung, J. (Creator), Kasela, S. (Creator), Katrinli, S. (Creator), Kuo, P.-L. (Creator), Matias-Garcia, P. R. (Creator), Mishra, P. (Creator), Nygaard, M. (Creator), Palviainen, T. (Creator), Patki, A. (Creator), Raffield, L. M. (Creator), Ratliff, S. M. (Creator), Richardson, T. G. (Creator), Robinson, O. (Creator), Soerensen, M. (Creator), Sun, D. (Creator), Tsai, P.-C. (Creator), van der Zee, M. D. (Creator), Walker, R. M. (Creator), Wang, X. (Creator), Wang, Y. (Creator), Xia, R. (Creator), Xu, Z. (Creator), Yao, J. (Creator), Zhao, W. (Creator), Correa, A. (Creator), Boerwinkle, E. (Creator), Dugué, P.-A. (Creator), Durda, P. (Creator), Elliott, H. R. (Creator), Gieger, C. (Creator), de Geus, E. J. C. (Creator), Harris, S. E. (Creator), Hemani, G. (Creator), Imboden, M. (Creator), Kähönen, M. (Creator), Kardia, S. L. R. (Creator), Kresovich, J. K. (Creator), Li, S. (Creator), Lunetta, K. L. (Creator), Mangino, M. (Creator), Mason, D. (Creator), McIntosh, A. M. (Creator), Mengel-From, J. (Creator), Moore, A. Z. (Creator), Murabito, J. M. (Creator), Ollikainen, M. (Creator), Pankow, J. S. (Creator), Pedersen, N. L. (Creator), Peters, A. (Creator), Polidoro, S. (Creator), Porteous, D. J. (Creator), Raitakari, O. (Creator), Rich, S. S. (Creator), Sandler, D. P. (Creator), Sillanpää, E. (Creator), Smith, A. K. (Creator), Southey, M. C. (Creator), Strauch, K. (Creator), Tiwari, H. (Creator), Tanaka, T. (Creator), Tillin, T. (Creator), Uitterlinden, A. G. (Creator), Van Den Berg, D. J. (Creator), van Dongen, J. (Creator), Wilson, J. G. (Creator), Wright, J. (Creator), Yet, I. (Creator), Arnett, D. (Creator), Bandinelli, S. (Creator), Bell, J. T. (Creator), Binder, A. M. (Creator), Boomsma, D. I. (Creator), Chen, W. (Creator), Christensen, K. (Creator), Conneely, K. N. (Creator), Elliott, P. (Creator), Ferrucci, L. (Creator), Fornage, M. (Creator), Hägg, S. (Creator), Hayward, C. (Creator), Irvin, M. (Creator), Kaprio, J. (Creator), Lawlor, D. A. (Creator), Lehtimäki, T. (Creator), Lohoff, F. W. (Creator), Milani, L. (Creator), Milne, R. L. (Creator), Probst-Hensch, N. (Creator), Reiner, A. P. (Creator), Ritz, B. (Creator), Rotter, J. I. (Creator), Smith, J. A. (Creator), Taylor, J. A. (Creator), van Meurs, J. B. J. (Creator), Vineis, P. (Creator), Waldenberger, M. (Creator), Deary, I. J. (Creator), Relton, C. L. (Creator), Horvath, S. (Creator) & Marioni, R. E. (Creator), figshare, 30 Jun 2021

  DOI: 10.6084/m9.figshare.c.5490114.v1

  Dataset

• Incidence trends of adult malignant brain tumors in Finland, 1990–2016

  Natukka, T. (Creator), Raitanen, J. (Creator), Haapasalo, H. (Creator) & Auvinen, A. (Creator), figshare, 15 Apr 2019

  DOI: 10.6084/m9.figshare.7993361.v1

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with Z902-A3

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8B9E/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with CB76

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8BAB/pdb

  Dataset

• Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with CDK2-IV

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8EX0/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with Bemcentinib

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8BA4/pdb

  Dataset

• Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with Reversine

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8EX1/pdb

  Dataset

• Crystal structure of JAK2 JH2-V617F in complex with Cdk2 inhibitor IV

  Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023

  DOI: 10.2210/pdb8B8N/pdb

  Dataset

• Supplementary information files for NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy Item

  Ranu, N. (Creator), Laitila, J. (Creator), Dugdale, H. F. (Creator), Mariano, J. (Creator), Kolb, J. S. (Creator), Wallgren-Pettersson, C. (Contributor), Witting, N. (Creator), Vissing, J. (Creator), Vilchez, J. J. (Creator), Fiorillo, C. (Creator), Zanoteli, E. (Creator), Auranen, M. (Creator), Jokela, M. (Creator), Tasca, G. (Creator), Claeys, K. G. (Creator), Voermans, N. C. (Creator), Palmio, J. (Creator), Huovinen, S. (Creator), Moggio, M. (Creator), Beck, T. N. (Creator), Kontrogianni-Konstantopoulos, A. (Contributor), Granzier, H. (Creator) & Ochala, J. (Creator), figshare, 4 May 2023

  DOI: 10.17028/rd.lboro.22761185.v1

  Dataset

• Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities

  Mehtonen, J. (Creator), Teppo, S. (Creator), Lahnalampi, M. (Creator), Kokko, A. (Creator), Kaukonen, R. (Creator), Oksa, L. (Creator), Bouvy-Liivrand, M. (Creator), Malyukova, A. (Creator), Mäkinen, A. (Creator), Laukkanen, S. (Creator), Mäkinen, P. (Creator), Rounioja, S. (Creator), Ruusuvuori, P. (Creator), Sangfelt, O. (Creator), Lund, R. (Creator), Lönnberg, T. (Creator), Lohi, O. (Creator) & Heinäniemi, M. (Creator), figshare, 21 Nov 2020

  DOI: 10.6084/m9.figshare.c.5214813.v1

  Dataset

• Childhood exposure to parental smoking and life-course overweight and central obesity

  Jaakkola, J. M. (Creator), Rovio, S. P. (Creator), Pahkala, K. (Creator), Viikari, J. (Creator), Rönnemaa, T. (Creator), Jula, A. (Creator), Niinikoski, H. (Creator), Mykkänen, J. (Creator), Juonala, M. (Creator), Hutri-Kähönen, N. (Creator), Kähönen, M. (Creator), Lehtimäki, T. (Creator) & Raitakari, O. T. (Creator), figshare, 22 Feb 2021

  DOI: 10.6084/m9.figshare.14074490.v1

  Dataset

• Methylation status of VTRNA2-1/nc886 is stable across populations, monozygotic twin pairs and in majority of tissues. Supplementary data

  Raitoharju, E. (Creator), Ollikainen, M. (Creator), Heikkinen, A. (Creator), Laakkonen, E. K. (Creator), Sillanpää, E. (Creator), Raitanen, J. (Creator), Luoto, R. (Creator), März, W. (Creator), E. Kleber, M. (Creator), Waldenberger, M. (Creator), Peters, A. (Creator), Delerue, T. (Creator), Hägg, S. (Creator), Jylhävä, J. (Creator), Kananen, L. (Creator), Kähönen, M. (Creator), Raitakari, O. (Creator), Lehtimäki, T. (Creator), Mishra, P. P. (Creator), Rajic, S. (Creator), Tamminen, H. (Creator) & Marttila, S. (Creator), figshare, 6 Oct 2022

  DOI: 10.25402/epi.21285384.v1

  Dataset

• The dental infections in patients undergoing preoperative dental examination before surgical treatment of saccular intracranial aneurysm

  Pyysalo, M. J. (Creator), Pyysalo, L. M. (Creator), Hiltunen, J. (Creator), Järnstedt, J. (Creator), Helminen, M. (Creator), Karhunen, P. (Creator) & Pessi, T. (Creator), figshare, 20 Aug 2018

  DOI: 10.6084/m9.figshare.c.4204811.v1

  Dataset

• Incidence trends of childhood central nervous system tumors in Finland 1990–2017

  Abuhamed, J. (Creator), Nikkilä, A. (Creator), Raitanen, J. (Creator), Alimam, W. (Creator), Lohi, O. (Creator), Pitkäniemi, J. (Creator), Haapasalo, H. (Creator) & Auvinen, A. (Creator), Zenodo, 17 Dec 2021

  DOI: 10.5281/zenodo.5789368

  Dataset