Neurological and Sensory diseases, Oncology, Surgical sciences

2025

Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity

Pesonen, E. K., Arponen, O., Niinimäki, J., Hernández, N., Pikkarainen, L., Tetri, S. & Korhonen, T. K., 18 Jan 2025, In: Scientific Reports. 15, 1, p. 2393 1 p.

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Assessment of improvement in functional outcomes between a novel knee replacement design and conventional designs in 240 patients: a randomized controlled trial

Irmola, T., Reito, A., Kangas, J., Eskelinen, A., Niemeläinen, M., Mattila, V. M. & Moilanen, T., 2025, In: ACTA ORTHOPAEDICA. 96, p. 127-134 8 p.

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Association of prostate-specific antigen density with prostate cancer mortality after a benign systematic prostate biopsy result

Pylväläinen, J., Talala, K., Raitanen, J., Rannikko, A. & Auvinen, A., 2025, (E-pub ahead of print) In: BJU International.

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Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma: Molecular Diagnostics

Elomaa, H., Tarkiainen, V., Äijälä, V. K., Sirniö, P., Ahtiainen, M., Sirkiä, O., Karjalainen, H., Kastinen, M., Tapiainen, V. V., Rintala, J., Meriläinen, S., Saarnio, J., Rautio, T., Tuomisto, A., Helminen, O., Wirta, E. V., Seppälä, T. T., Böhm, J., Mäkinen, M. J. & Mecklin, J. P. & 1 others, Väyrynen, J. P., 2025, (E-pub ahead of print) In: British Journal of Cancer. 1119992.

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Blood biomarkers to identify patients with different intracranial lesion combinations after traumatic brain injury

Koivikko, P., Katila, A. J., Takala, R. S., Hossain, I., Luoto, T. M., Raj, R., Koivisto, M., Tenovuo, O., Blennow, K., Hutchinson, P., Maanpää, H. R., Mohammadian, M., Newcombe, V. F., Sanchez, J. C., Tallus, J., van Gils, M., Zetterberg, H. & Posti, J. P., Jan 2025, In: Brain and Spine. 5, 11 p., 104195.

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CDX2 and SATB2 loss are associated with myeloid cell infiltration and poor survival in colorectal cancer

Sirniö, P., Elomaa, H., Tuomisto, A., Äijälä, V. K., Karjalainen, H., Kastinen, M., Tapiainen, V. V., Sirkiä, O., Ahtiainen, M., Helminen, O., Wirta, E. V., Rintala, J., Meriläinen, S., Saarnio, J., Rautio, T., Seppälä, T. T., Böhm, J., Mecklin, J. P., Mäkinen, M. J. & Väyrynen, J. P., Feb 2025, In: Cancer Immunology, Immunotherapy. 74, 4, 12 p., 111.

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Chronic occupational paronychia secondary to digital pilonidal sinus from dog grooming

Räisänen, M. P., Furu, H., Reito, A. & Bindra, R. R., 2025, In: JOURNAL OF OCCUPATIONAL HEALTH. 67, 1, 4 p., uiae076.

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Comprehensive characterization of micropapillary colorectal adenocarcinoma

Äijälä, V. K., Härkönen, J., Mantere, T., Elomaa, H., Sirniö, P., Pohjanen, V. M., Sirkiä, O., Karjalainen, H., Kastinen, M., Tapiainen, V. V., Väyrynen, S. A., Pölönen, P., Ahtiainen, M., Helminen, O., Wirta, E. V., Rintala, J., Meriläinen, S., Saarnio, J., Rautio, T. & Pylkäs, K. & 6 others, Seppälä, T. T., Böhm, J., Mecklin, J. P., Tuomisto, A., Mäkinen, M. J. & Väyrynen, J. P., 2025, (E-pub ahead of print) In: Journal of Pathology. 14 p.

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Computed tomography-determined high visceral adipose tissue and sarcopenic obesity and their associations with survival in vulnerable or frail older adults with cancer considered for systemic anticancer treatment

Tolonen, A., Lehtomäki, K., Kerminen, H., Huhtala, H., Bärlund, M., Österlund, P. & Arponen, O., Mar 2025, In: JOURNAL OF GERIATRIC ONCOLOGY. 16, 2, 13 p., 102171.

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Development and Validation Study of a Screening Questionnaire to Identify People Who Are Physically Inactive

Kenttä, E., Sievänen, H., Verho, A., Paajanen, M., Lukkarinen, T., Vähä-Ypyä, H., Raitanen, J., Tokola, K., Vasankari, T. & Parkkari, J., Mar 2025, In: Public Health Challenges. 4, 1, 9 p., e70037.

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Effect of Baseline Adjacent Segment Degeneration on Clinical Outcomes After Lumbar Fusion

Toivonen, L. A., Mäntymäki, H., Benneker, L. M., Kautiainen, H. & Neva, M. H., 2025, (E-pub ahead of print) In: GLOBAL SPINE JOURNAL. 8 p.

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Effect of NSAID Consumption on Renal Cell Carcinoma Prognosis: A Population-Based Study

Kemppinen, I., Pöyhönen, A., Veskimäe, P., Veitonmäki, T., Tammela, T. & Murtola, T. J., Jun 2025, In: CLINICAL GENITOURINARY CANCER. 23, 3, 6 p., 102311.

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Endolymphatic hydrops impairs inner ear uptake and distribution of intratympanically injected gadolinium mixed with dexamethasone in patients with Meniere’s disease

Zou, J., Li, H., Zhu, M., Chen, L., Wang, Z., Lu, T., Chen, Y., Lu, J. & Pyykkö, I., 2025, (E-pub ahead of print) In: European Archives of Oto-Rhino-Laryngology. 9 p.

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Enhancing Extended Reality assisted surgery through a Field-of-View video delivery optimization

Alekseeva, D., Mezina, A., Burget, R., Arponen, O., Lohan, E. S. & Ometov, A., 2025, In: Computer Networks. 259, 18 p., 111093.

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Favourable Outcome of Relapsed PCNSL Among Transplant Eligble Patients

Pellonperä, E., Puhakka, I., Kuitunen, H., Rönkä, A., Sunela, K., Kuusisto, M. E. L., Klaavuniemi, T., Jäkälä, P., Rajamäki, A., Arkko, U. M. & Kuittinen, O., 2025, (E-pub ahead of print) In: EUROPEAN JOURNAL OF HAEMATOLOGY. 7 p.

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Finnish translation, validation, and reproducibility of BREAST-Q modules relevant to breast cancer treatment

Homsy, P., Repo, J., Kuhlefelt, C., Lindford, A., Ihalainen, H., Kauhanen, S. & Jahkola, T., 2025, In: Scandinavian Journal of Surgery. 114, 1, p. 65-72 8 p.

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First-line glaucoma monotherapy medication patterns in Finland during 1995–2019 based on a population-based study

Purola, P. K. M., Koskinen, S. V. P. & Uusitalo, H. M. T., Jan 2025, In: PLoS ONE. 20, 1 January, 16 p., e0316835.

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Forecasting Mortality Associated Emergency Department Crowding with LightGBM and Time Series Data

Nevanlinna, J., Eidstø, A., Ylä-Mattila, J., Koivistoinen, T., Oksala, N., Kanniainen, J., Palomäki, A. & Roine, A., 15 Jan 2025, In: Journal of Medical Systems. 49, 1, 1 p., 9.

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Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours

Mishra, S., Tejesvi, M. V., Hekkala, J., Turunen, J., Kandikanti, N., Kaisanlahti, A., Suokas, M., Leppä, S., Vihinen, P., Kuitunen, H., Sunela, K., Koivunen, J., Jukkola, A., Kalashnikov, I., Auvinen, P., Kääriäinen, O. S., Peñate Medina, T., Peñate Medina, O., Saarnio, J. & Meriläinen, S. & 10 others, Rautio, T., Aro, R., Häivälä, R., Suojanen, J., Laine, M., Erawijattari, P. P., Lahti, L., Karihtala, P., Ruuska, T. S. & Reunanen, J., 2025, In: Journal of Advanced Research. 68, p. 375-386 12 p.

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6 Citations (Scopus)

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How Universal Adhesive Systems With Nanoencapsulated Flavonoids Improve Long-Term Bonding to Caries-Affected Dentin

Falconi-Páez, C., Aldaz, M. A. N., Navarro, T. G., González-Vaca, C. C., Campos, L. A., Davila-Sanchez, A. & Arrais, C. A. G., 2025, (E-pub ahead of print) In: JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY.

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Human papillomavirus E6 alters Toll-like receptor 9 transcripts and chemotherapy responses in breast cancer cells in vitro

Parviainen, E., Nurmenniemi, S., Ravaioli, S., Bravaccini, S., Manninen, A., Jukkola, A. & Selander, K., 2025, In: MOLECULAR BIOLOGY REPORTS. 52, 1, 12 p., 43.

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Impact of signs and symptoms of dry eye disease on health-related quality of life: a cross-sectional population study among older adults

Aapola, U., Mosallaei, P., Nättinen, J., Suurkuukka, I., Tuomilehto, J., Keinänen-Kiukaanniemi, S., Saramies, J. & Uusitalo, H., 2025, (E-pub ahead of print) In: QUALITY OF LIFE RESEARCH. 14 p.

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Incidence of constrained condylar and hinged knee implants and mid-to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA)

VON HINTZE, J., Ponkilainen, V., W-Dahl, A., Hailer, N. P., Furnes, O., Fenstad, A. M., Badawy, M., Pedersen, A. B., Lindberg-Larsen, M., Niemeläinen, M. J., Mäkelä, K. & Eskelinen, A., 2025, In: ACTA ORTHOPAEDICA. 96, p. 142-150 9 p.

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Incidence trends of surgical complications after oesophagectomy for oesophageal cancer: a population-based, nationwide cohort study in Finland over 30 years

Sirviö, V. E. J., Räsänen, J. V., Helminen, O., Helmiö, M., Huhta, H., Kallio, R., Koivukangas, V., Kokkola, A., Laine, S., Lietzen, E., Meriläinen, S., Pohjanen, V. M., Rantanen, T., Ristimäki, A., Saarnio, J., Sihvo, E., Toikkanen, V., Tyrväinen, T., Uimonen, M. & Valtola, A. & 1 others, Kauppila, J. H., 2025, In: World Journal of Surgical Oncology. 23, 1, 10 p., 59.

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Increased PD-1 expression in livers associated with PD-1-antibody-induced hepatotoxicity

Saarela, M., Parviainen, E., Lleo, A., di Tommaso, L., Raunio, H., Kankaanranta, K., Vuopala, K., Rönkä, A., Nurmenniemi, S., Kallio, R., Jukkola, A. & Selander, K. S., 23 Jan 2025, In: Bmc Immunology. 26, 1, 6 p., 4.

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Interplay of atherosclerosis and medial degeneration in human ascending aorta

Huhta, A., Paavonen, T., Mennander, A. & Kholová, I., Jan 2025, In: Cardiovascular Pathology. 74, 11 p., 107702.

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Keloid vasculature reacts to intralesional injection therapies but does not predict the response to treatment: Biopsies from double-blinded, randomized, controlled trial

Komulainen, T., Hietanen, K. E., Tolonen, T., Parkkila, S., Kaartinen, I. S. & Järvinen, T. A. H., Jun 2025, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1871, 5, 167790.

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Knee laxity, joint hypermobility, femoral anteversion, hamstring extensibility and navicular drop as risk factors for non-contact ACL injury in female athletes: A 4.5-year prospective cohort study

Pasanen, K., Seppänen, A., Leppänen, M., Tokola, K., Järvelä, T., Vasankari, T., Myklebust, G., Krosshaug, T. & Parkkari, J., 2025, (E-pub ahead of print) In: Knee Surgery, Sports Traumatology, Arthroscopy.

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Lifetime Treatment Trajectories of Mantle Cell Lymphoma: Simulation Based Analysis of 20 Years of Real-World Data

Harmanen, M., Hujo, M., Sund, R., Sorigue, M., Khan, M., Prusila, R., Klaavuniemi, T., Kari, E., Jantunen, E., Sunela, K., Rajamäki, A., Alanne, E., Kuitunen, H., Sancho, J. M., Jukkola, A., Rönkä, A. & Kuittinen, O., Jan 2025, In: HEMATOLOGICAL ONCOLOGY. 43, 1, e70024.

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Magnetic Resonance Imaging – Derived Psoas Muscle Area and Survival in Patients Treated Invasively for Peripheral Arterial Disease

Söderlund, M., Huhtamo, H., Protto, S., Hernesniemi, J. A., Vakhitov, D., Oksala, N. & Khan, N., Mar 2025, In: Scandinavian Journal of Surgery. 114, 1, p. 44-55 12 p.

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Major regional differences in the use of labor analgesia in Finland – A national register study

Haapanen, M., Ponkilainen, V. & Kuitunen, I., Feb 2025, In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 305, p. 62-66 5 p.

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Mental health indicators in pharmaceutical sciences students during the COVID-19 pandemic

Guimarães, L. A., Arrais Campos, L., Martins, B. G., Silva, B. N. S., Marôco, J. & Campos, J. A. D. B., Mar 2025, In: Currents in Pharmacy Teaching and Learning. 17, 3, 102212.

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Minimal important change of the Western Ontario Osteoarthritis of the Shoulder (WOOS) index in patients with glenohumeral osteoarthritis and rotator cuff tear arthropathy

Larsen, J. B., Thillemann, T. M., Launonen, A. P., Østergaard, H. K., Falstie-Jensen, T., Sumrein, B., Zivanovic, S., Jensen, S. L., Mechlenburg, I. & Ponkilainen, V., 2025, In: Archives of Orthopaedic and Trauma Surgery. 145, 1, 162.

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Neovascular age-related macular degeneration on three nationwide survey and register data in Finland during 2000–2017

Purola, P., Koskinen, S., Kaarniranta, K. & Uusitalo, H., 2025, (E-pub ahead of print) In: Acta Ophthalmologica.

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Preoperative predictors of postoperative complications after gastrectomy for gastric cancer, a population-based study in Finland

FINEGO group, Putila, E., Helminen, O., Helmiö, M., Huhta, H., Jalkanen, A., Junttila, A., Kallio, R., Koivukangas, V., Kokkola, A., Lietzen, E., Louhimo, J., Meriläinen, S., Pohjanen, V. M., Rantanen, T., Ristimäki, A., Räsänen, J. V., Sihvo, E., Toikkanen, V. & Tyrväinen, T. & 2 others, Valtola, A. & Kauppila, J. H., Jun 2025, In: European Journal of Surgical Oncology. 51, 6, 109682.

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Principles of good practice for translation of electronic clinical outcome assessments

Shalhoub, H., Turner, M., Bradley-Gilbride, A., Eremenco, S., Muehlan, H., Parks-Vernizzi, E., Arnold, B., Kuliś, D., Anfray, C., Chaplin, J. E. & Repo, J. P., 4 Mar 2025, In: Journal of Patient-Reported Outcomes. 9, 1, 26.

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Prognostic Features and Potential for Immune Therapy in Metastatic Mismatch Repair-Deficient Colorectal Cancer: A Retrospective Analysis of a Large Consecutive Population-Based Patient Series

Wirta, E.-V., Elomaa, H., Mecklin, J.-P., Seppälä, T. T., Hyöty, M., Böhm, J., Ahtiainen, M. & Väyrynen, J. P., Jan 2025, In: Cancer Medicine. 14, 1, e70555.

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Prototype master protocol for benchmarking of real-world follow-up data in glaucoma

Hujanen, P., Tuulonen, A., Leinonen, S., Vepsäläinen, K., Jóhannesson, G., Vaajanen, A., Lehtonen, E. & Uusitalo-Jarvinen, H., 2025, (E-pub ahead of print) In: Acta Ophthalmologica.

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Repeated heart rate variability monitoring after myocardial infraction: Cohort profile of the MI-ECG study

Pukkila, T., Rankinen, J., Lyytikäinen, L. P., Oksala, N., Nikus, K., Räsänen, E. & Hernesniemi, J., Apr 2025, In: IJC Heart and Vasculature. 57, 101619.

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Screening of homing and tissue-penetrating peptides by microdialysis and in vivo phage display

Pemmari, T., Prince, S., Wiss, N., Kõiv, K., May, U., Mölder, T., Sudakov, A., Caro, F. M., Lehtonen, S., Uusitalo-Järvinen, H., Teesalu, T. & Järvinen, T. A. H., 2025, In: Life science alliance. 8, 5, e202201490.

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Shear wave elastography as a marker of anisotropy in denervated muscle tissue

Kutvonen, O., Himanen, S.-L. & Mäkelä, K., 2025, In: Clinical Neurophysiology Practice. 10, p. 95-103 9 p.

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Ten-Year Heterogeneity of Minimal Important Change and Patient Acceptable Symptom State After Lumbar Fusions

Toivonen, L. A., Laurén, J. L. C., Kautiainen, H., Häkkinen, A. H. & Neva, M. H., 1 Jan 2025, In: Spine. 50, 1, p. 46-52 7 p.

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Testosterone levels at diagnosis: A key predictor of overall survival among patients with prostate cancer

Jussila, I., Ahtiainen, J. P., Laakkonen, E. K., Käkelä, P., Parviainen, M., Pohjolainen, H., Aaltonen, J., Onni, N., Mikko, K., Murtola, T. J., Huhtala, H. & Seikkula, H., Feb 2025, In: BJUI Compass. 6, 2, e484.

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