Alfonso Urbanucci

Research output

Research output per year 2008 2011 2012 2021 2022

• 9 Article
• 1 Doctoral thesis
• 1 Review Article
• 1 Preprint

Research output per year

Research output per year

Search results

• 2022

  Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression

  Cao, S., Wang, J. R., Ji, S., Yang, P., Dai, Y., Guo, S., Montierth, M. D., Shen, J. P., Zhao, X., Chen, J., Lee, J. J., Guerrero, P. A., Spetsieris, N., Engedal, N., Taavitsainen, S., Yu, K., Livingstone, J., Bhandari, V., Hubert, S. M., Daw, N. C., & 20 othersFutreal, P. A., Efstathiou, E., Lim, B., Viale, A., Zhang, J., Nykter, M., Czerniak, B. A., Brown, P. H., Swanton, C., Msaouel, P., Maitra, A., Kopetz, S., Campbell, P., Speed, T. P., Boutros, P. C., Zhu, H., Urbanucci, A., Demeulemeester, J., Van Loo, P. & Wang, W., 2022, In: Nature Biotechnology. 40, 11, p. 1624–1633

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

  • Messenger RNA 100%
  • Tumors 72%
  • Cells 69%
  • Disease Progression 57%
  • Neoplasms 23%
  5 Downloads (Pure)
• 2021

  Chromatin and epigenetic dysregulation of prostate cancer development, progression, and therapeutic response

  Kukkonen, K., Taavitsainen, S., Huhtala, L., Uusi-Makela, J., Granberg, K. J., Nykter, M. & Urbanucci, A., Jul 2021, In: Cancers. 13, 13, 3325.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

  • Chromatin 100%
  • Epigenomics 98%
  • Prostatic Neoplasms 89%
  • Cell Plasticity 60%
  • Neoplasms 36%
  29 Downloads (Pure)

• Gene regulation network analysis on human prostate orthografts highlights a potential role for the JMJD6 regulon in clinical prostate cancer

  Cangiano, M., Grudniewska, M., Salji, M. J., Nykter, M., Jenster, G., Urbanucci, A., Granchi, Z., Janssen, B., Hamilton, G., Leung, H. Y. & Beumer, I. J., 2021, In: Cancers. 13, 9, 2094.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

  • Regulon 100%
  • Gene Regulatory Networks 82%
  • Prostate 63%
  • Prostatic Neoplasms 60%
  • Recurrence 23%
  1 Downloads (Pure)

• Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse

  Taavitsainen, S., Engedal, N., Cao, S., Handle, F., Erickson, A., Prekovic, S., Wetterskog, D., Tolonen, T., Vuorinen, E. M., Kiviaho, A., Nätkin, R., Häkkinen, T., Devlies, W., Henttinen, S., Kaarijärvi, R., Lahnalampi, M., Kaljunen, H., Nowakowska, K., Syvälä, H., Bläuer, M., & 13 othersCremaschi, P., Claessens, F., Visakorpi, T., Tammela, T. L. J., Murtola, T., Granberg, K. J., Lamb, A. D., Ketola, K., Mills, I. G., Attard, G., Wang, W., Nykter, M. & Urbanucci, A., 2021, In: Nature Communications. 12, 1, 5307.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

  • Enzalutamide 100%
  • RNA Sequencing 88%
  • Transposases 75%
  • sequencing 72%
  • chromatin 69%
  47 Downloads (Pure)
• 2020

  Chromatin accessibility analysis uncovers regulatory element landscape in prostate cancer progression

  Uusi-Mäkelä, J., Afyounian, E., Tabaro, F., Häkkinen, T., Lussana, A., Shcherban, A., Annala, M., Nurminen, R., Kivinummi, K., Tammela, T. L. J., Urbanucci, A., Latonen, L., Kesseli, J., Granberg, K. J., Visakorpi, T. & Nykter, M., 9 Sept 2020.

  Research output: Working paper › Preprint › Scientific
• 2012

  Androgen receptor (AR) aberrations in castration-resistant prostate cancer

  Waltering, K., Urbanucci, A. & Visakorpi, T., 2012, In: Molecular and Cellular Endocrinology. 360, 1-2, p. 38-43

  Research output: Contribution to journal › Article › Scientific › peer-review
  112 Citations (Scopus)

• Androgen receptor overexpression alters binding dynamics of the receptor to chromatin and chromatin structure

  Urbanucci, A., Marttila, S., Jänne, O. A. & Visakorpi, T., 2012, In: The Prostate. 72, 11, p. 1223-1232 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Androgen Receptors 100%
  • Chromatin 82%
  • Serine Proteases 44%
  • Prostate-Specific Antigen 40%
  • RNA Polymerase II 30%
  16 Citations (Scopus)

• Chemical castration and anti-androgens induce differential gene expression in prostate cancer

  Lehmusvaara, S., Erkkilä, T., Urbanucci, A., Waltering, K., Seppälä, J., Larjo, A., Tuominen, V., Isola, J., Kujala, P., Lähdesmäki, H., Kaipia, A., Tammela, T. & Visakorpi, T., 2012, In: Journal of Pathology. 227, 3, p. 336-345

  Research output: Contribution to journal › Article › Scientific › peer-review
  25 Citations (Scopus)

• Overexpression of Androgen Receptor in Prostate Cancer

  Urbanucci, A., 2012, Tampere. 95 p.

  Research output: Book/Report › Doctoral thesis › Collection of Articles
• 2011

  Androgen Regulation of micro-RNAs in Prostate Cancer

  Waltering, K., Porkka, K. P., Jalava, S. E., Urbanucci, A., Kohonen, P. J., Latonen, L. M., Kallioniemi, O., Jenster, G. & Visakorpi, T., 2011, In: Prostate. 71, 6, p. 604-614

  Research output: Contribution to journal › Article › Scientific › peer-review
  122 Citations (Scopus)

• Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer

  Urbanucci, A., Sahu, B., Seppälä, J., Larjo, A., Latonen, LM., Waltering, K., Tammela, T., Vessella, R., Lähdesmäki, H., Jänne, O. & Visakorpi, T., 2011, In: Oncogene. 31, 17, p. 2153-2163

  Research output: Contribution to journal › Article › Scientific › peer-review
  86 Citations (Scopus)
• 2008

  Androgen regulation of the androgen receptor coregulators

  Urbanucci, A., Waltering, K. K., Suikki, H. E., Helenius, M. A. & Visakorpi, T., 2008, In: BMC Cancer. 8, 219, p. 10 p

  Research output: Contribution to journal › Article › Scientific › peer-review
  51 Citations (Scopus)