Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Anniina Virtanen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity
Miao, Y., Virtanen, A., Zmajkovic, J., Hilpert, M., Skoda, R. C., Silvennoinen, O. & Haikarainen, T., 2024, In: Journal of Medicinal Chemistry. 67, 12, p. 10012–10024 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling
Abraham, B. G., Haikarainen, T., Vuorio, J., Girych, M., Virtanen, A. T., Kurttila, A., Karathanasis, C., Heilemann, M., Sharma, V., Vattulainen, I. & Silvennoinen, O., Mar 2024, In: Science Advances. 10, 10, eadl2097.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Downloads (Pure) -
Development of an enzyme-coupled activity assay for Janus kinase 2 inhibitor screening
Pölläniemi, A., Virtanen, A., Silvennoinen, O. & Haikarainen, T., Jun 2023, In: SLAS Discovery. 28, 4, p. 180-187 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)8 Downloads (Pure) -
Differences in JAK Isoform Selectivity Among Different Types of JAK Inhibitors Evaluated for Rheumatic Diseases Through In Vitro Profiling
Virtanen, A., Palmroth, M., Liukkonen, S., Kurttila, A., Haikarainen, T., Isomäki, P. & Silvennoinen, O., 2023, In: Arthritis and Rheumatology. 75, 11, p. 2054-2061 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile6 Citations (Scopus)26 Downloads (Pure) -
Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
Virtanen, A. T., Haikarainen, T., Sampathkumar, P., Palmroth, M., Liukkonen, S., Liu, J., Nekhotiaeva, N., Hubbard, S. R. & Silvennoinen, O., Jan 2023, In: Pharmaceuticals. 16, 1, 17 p., 75.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile8 Citations (Scopus)24 Downloads (Pure)
Datasets
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Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1
Arwood, M. L. (Creator), Liu, Y. (Creator), Harkins, S. K. (Creator), Weinstock, D. M. (Creator), Yang, L. (Creator), Stevenson, K. E. (Creator), Plana, O. D. (Creator), Dong, J. (Creator), Cirka, H. (Creator), Jones, K. L. (Creator), Virtanen, A. T. (Creator), Gupta, D. G. (Creator), Ceas, A. (Creator), Lawney, B. (Creator), Yoda, A. (Creator), Leahy, C. (Creator), Hao, M. (Creator), He, Z. (Creator), Choi, H. G. (Creator), Wang, Y. (Creator), Silvennoinen, O. (Creator), Hubbard, S. R. (Creator), Zhang, T. (Creator), Gray, N. S. (Creator) & Li, L. S. (Creator), Protein Data Bank (PDB), 21 Jun 2023
DOI: 10.2210/pdb7TEU/pdb
Dataset
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Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with CDK2-IV
Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023
DOI: 10.2210/pdb8EX0/pdb
Dataset
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Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with HTSA3
Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Contributor), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023
DOI: 10.2210/pdb8EX2/pdb
Dataset
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Crystal structure of JAK2 JH2-V617F in complex with Bemcentinib
Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023
DOI: 10.2210/pdb8BA4/pdb
Dataset
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Crystal structure of JAK2 JH2-V617F in complex with Cdk2 inhibitor IV
Virtanen, A. T. (Creator), Haikarainen, T. (Creator), Sampathkumar, P. (Creator), Palmroth, M. (Creator), Liukkonen, S. (Creator), Liu, J. (Creator), Nekhotiaeva, N. (Creator), Hubbard, S. R. (Creator) & Silvennoinen, O. (Creator), Protein Data Bank (PDB), 1 Feb 2023
DOI: 10.2210/pdb8B8N/pdb
Dataset