Research output per year
Research output per year
- 33 results
Search results
-
2024
Progression of herpesvirus infection remodels mitochondrial organization and metabolism
Leclerc, S., Gupta, A., Ruokolainen, V., Chen, J.-H., Kunnas, K., Ekman, A. A., Niskanen, H., Belevich, I., Vihinen, H., Turkki, P., Perez-Berna, A. J., Kapishnikov, S., Mäntylä, E., Harkiolaki, M., Dufour, E., Hytönen, V., Pereiro, E., McEnroe, T., Fahy, K. & Kaikkonen, M. U. & 6 others, , 15 Apr 2024, (E-pub ahead of print) In: PLOS PATHOGENS. 20, 4, e1011829.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
Species-specific variation in mitochondrial genome tandem repeat polymorphisms in hares (Lepus spp., Lagomorpha, Leporidae) provides insight into their evolution
Tapanainen, R., Aasumets, K., Fekete, Z., Goffart, S., Dufour, E. & L. O. Pohjoismäki, J., 30 Oct 2024, In: Gene. 926, 148644.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
2023
Molecular phenotyping uncovers differences in basic housekeeping functions among closely related species of hares (Lepus spp., Lagomorpha: Leporidae)
Gaertner, K., Michell, C., Tapanainen, R., Goffart, S., Saari, S., Soininmäki, M., Dufour, E. & Pohjoismäki, J. L. O., Aug 2023, In: MOLECULAR ECOLOGY. 32, 15, p. 4097-4117Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)6 Downloads (Pure) -
2022
The transcription factor network of E. coli steers global responses to shifts in RNAP concentration
Almeida, B. L. B., Bahrudeen, M. N. M., Chauhan, V., Dash, S., Kandavalli, V., Häkkinen, A., Lloyd-Price, J., Cristina, P. S. D., Baptista, I. S. C., Gupta, A., Kesseli, J., Dufour, E., Smolander, O.-P., Nykter, M., Auvinen, P., Jacobs, H. T., Oliveira, S. M. D. & Sanches Ribeiro, A., 8 Jul 2022, In: Nucleic Acids Research. 50, 12, p. 6801-6819 19 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
2020
A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1
González de Cózar, J. M., Carretero-Junquera, M., Ciesielski, G. L., Miettinen, S. M., Varjosalo, M., Kaguni, L. S., Dufour, E. & Jacobs, H. T., 1 Nov 2020, In: JOURNAL OF BIOCHEMISTRY. 168, 5, p. 515-533 19 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)18 Downloads (Pure) -
Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: Switch from RET and ROS to FET
Szibor, M., Gellerich, F., Moore, A. L., Gainutdinov, T., Fernandez-Vizarra, E., Dufour, E., Gizatullina, Z., Debska-Vielhaber, G., Heidler, J., Wittig, I. & Viscomi, C., 2020, In: Biochimica et Biophysica Acta - Bioenergetics. 1861, 2, 148137.Research output: Contribution to journal › Article › Scientific › peer-review
44 Citations (Scopus) -
Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing
Sommers, N., Saraji, A., Petrovic, A., Quanz, K., Heckert, M., Kumar, M., Wahl, J., Kraut, S., Seeger, W., Schermuly, R. T., Ghofrani, H. A., Alebrahimdehkordi, N., Ramser, K., Braun, T., Jacobs, H. T., Weissmann, N., Szibor, M., Pak, O., Knoepp, F. & Strielkov, I. & 4 others, , 2020, In: Science Advances. 6, 16, eaba0694.Research output: Contribution to journal › Article › Scientific › peer-review
46 Citations (Scopus) -
Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila
Yalgin, C., Rovenko, B., Andjelković, A., Neefjes, M., Oymak, B., Dufour, E., Hietakangas, V. & Jacobs, H. T., 21 Aug 2020, In: Iscience. 23, 8, 101362.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)7 Downloads (Pure) -
Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia
Szibor, M., Nyman, T. A., Gärtner, U., Hall, A. R., Pell, V., Viscomi, C., Krieg, T., Murphy, M. P., Braun, T., Gellerich, F. N., Schlüter, K.-D., Schreckenberg, R., Jacobs, H. T., Gizatullina, Z., Dufour, E., Wiesnet, M., Dhandapani, P. K., Debska-Vielhaber, G., Heidler, J. & Wittig, I., 2020, In: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 24, 6, p. 3534-3548Research output: Contribution to journal › Article › Scientific › peer-review
17 Citations (Scopus) -
2019
Alternative oxidase confers nutritional limitation on Drosophila development
Saari, S., Kemppainen, E., Tuomela, T., Oliveira, M. T., Dufour, E. & Jacobs, H., 2019, In: Journal of experimental zoology part a: ecological and integrative physiology. 331, 6, p. 341-356Research output: Contribution to journal › Article › Scientific › peer-review
5 Citations (Scopus) -
Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells
Lietzén, N., Hirvonen, K., Honkimaa, A., Buchacher, T., Laiho, J. E., Oikarinen, S., Mazur, M. A., Flodström-Tullberg, M., Dufour, E., Hyöty, H., Lahesmaa, R. & Sioofy-Khojine, A.-B., 2019, In: Iscience. 19, p. 340-357Research output: Contribution to journal › Article › Scientific › peer-review
19 Citations (Scopus) -
Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms
Bahhir, D., Andjelkovic, A., Dufour, E., González de Cózar, J. M., Gerards, M., Parhiala, M., Pamplona, R., Jacobs, H., Jõers, P., Gonzalez de Cozar, J., Yalgin, C., Ots, L., Järvinen, S., George, J., Naudí, A., Krama, T., Krams, I. & Tamm, M., 2019, In: PLoS Genetics. 15, 10, e1008410.Research output: Contribution to journal › Article › Scientific › peer-review
7 Citations (Scopus) -
Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice
Dhandapani, P. K., Lyyski, A. M., Paulin, L., Khan, N. A., Suomalainen, A., Auvinen, P., Dufour, E., Szibor, M. & Jacobs, H., 2019, In: Physiological reports. 7, 13, e14159.Research output: Contribution to journal › Article › Scientific › peer-review
9 Citations (Scopus) -
RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA
Gerards, M., Teeri, E., George, J., Dufour, E., Jacobs, H. T., Jõers, P. & Gonzalez de Cozar, J., 2019, In: Journal of Biological Chemistry. 294, 12, p. 4331-4344Research output: Contribution to journal › Article › Scientific › peer-review
12 Citations (Scopus) -
Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells
Pulli, I., Toivola, D. M., Dufour, E., Sanz, A., Cooper, H. M., Parys, J. B., Törnquist, K., Löf, C., Blom, T., Asghar, M. Y., Lassila, T., Bäck, N., Lin, K.-L., Nyström, J. H. & Kemppainen, K., 2019, In: Biochimica et biophysica acta - molecular cell research. 1866, 9, p. 1475-1486Research output: Contribution to journal › Article › Scientific › peer-review
8 Citations (Scopus) -
2018
Expression of the Alternative Oxidase Influences Jun N-Terminal Kinase Signaling and Cell Migration
Andjelkovic, A., Jacobs, H., Mordas, A., Bruinsma, L., Ketola, A., Cannino, G., Giordano, L., Dhandapani, P., Szibor, M. & Dufour, E., 2018, In: MOLECULAR AND CELLULAR BIOLOGY. 38, 24, p. e00110-18Research output: Contribution to journal › Article › Scientific › peer-review
10 Citations (Scopus) -
Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells
Toompuu, M., Tuomela, T., Laine, P., Paulin, L., Dufour, E. & Jacobs, H., 2018, In: Nucleic Acids Research. 46, 10, p. 5209-5226Research output: Contribution to journal › Article › Scientific › peer-review
19 Citations (Scopus) -
Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model
Luukinen, H., Hammarén, M., Vanha-Aho, L., Svorjova, A., Kantanen, L., Järvinen, S., Luukinen, B., Dufour, E., Rämet, M., Hytönen, V., Parikka, M. & Vanha-aho, L.-M., 2018, In: Disease Models and Mechanisms. 11, 1, p. dmm031658Research output: Contribution to journal › Article › Scientific › peer-review
9 Citations (Scopus) -
2017
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology
Szibor, M., Dhandapani, P., Dufour, E., Holmström, K., Zhuang, Y., Salwig, I., Wittig, I., Heidler, J., Zemfira, G., Gizatullina, Z., Gainutdinov, T., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Nandania, J., Velagapudi, V., Wietelmann, A., Rustin, P., Gellerich, F. & Jacobs, H. & 1 others, , 2017, In: Disease Models & Mechanisms. 10, 2, p. 163-171Research output: Contribution to journal › Article › Scientific › peer-review
54 Citations (Scopus) -
Development of an inducible platform for intercellular protein delivery
Siller, R., Dufour, E., Lycke, M., Wilmut, I., Jung, Y.-W., Park, I. H. & Sullivan, G. J., 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 1-10Research output: Contribution to journal › Article › Scientific › peer-review
3 Citations (Scopus) -
2016
TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions
Martinez-Reyes, I., Diebold, L. P., Kong, H., Schieber, M., Huang, H., Hensley, C. T., Mehta Manan, M., Mehta, M., Tianyuan, W., Wang, T., Santos, J. H., Woychik, R., Dufour, E., Spelbrink, J. N., Weinberg, S. E., Yingming, Z., Zhao, Y., DeBerardinis, R. J. & Chandel, N. S., 2016, In: MOLECULAR CELL. 61, 2, p. 199-209Research output: Contribution to journal › Article › Scientific › peer-review
385 Citations (Scopus) -
2015
DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells
Kontro, H., Cannino, G., Rustin, P., Dufour, E. & Kainulainen, H., 2015, In: PLoS ONE. 10, 7, p. e0131990 e0131990.Research output: Contribution to journal › Article › Scientific › peer-review
14 Citations (Scopus) -
Diiron centre mutations in Ciona intestinalis alternative oxidase abolish enzymatic activity and prevent rescue of cytochrome oxidase deficiency in flies
Andjelkovic, A., Oliveira, M. T., Cannino, G., Yalgin, C., Dhandapani, P. K., Dufour, E., Rustin, P., Szibor, M. & Jacobs, H. T., 2015, In: Scientific reports. 5, p. 18295 18295.Research output: Contribution to journal › Article › Scientific › peer-review
14 Citations (Scopus) -
2014
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
Wheaton, W. W., Scott, B. G. R., Chandel, N. S., Weinberg, S. E., Hamanaka, R. B., Soberanes, S., Sullivan, L. B., Anso, E., Glasauer, A., Dufour, E. & Mutlu, G., 2014, In: eLIFE. 3, e02242.Research output: Contribution to journal › Article › Scientific › peer-review
831 Citations (Scopus) -
Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase
Fukuoh, A., Cannino, G., Gerards, M., Buckley, S., Kazancioglu, S., Scialo, F., Lihavainen, E., Ribeiro, A., Dufour, E. & Jacobs, H. T., 2014, In: Molecular Systems Biology. 10, 734, p. 1-21 21 p.Research output: Contribution to journal › Article › Scientific › peer-review
35 Citations (Scopus) -
The proto-oncemetabolite fumarate binds glutathione to amplify ROS-dependent signaling
Sullivan, L., Martinez-Gardia, E., Nguyen, H. & Dufour, E., 2014, In: MOLECULAR CELL. 51, 2, p. 236-48Research output: Contribution to journal › Article › Scientific › peer-review
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2013
Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction
El-Khoury, R., Dufour, E., Rak, M., Ramanantsoa, N., Grandchamp, N., Csaba, Z., Duvillié, B., Bénit, P., Gallego, J., Gressens, P., Sarkis, C., Jacobs, H. T. & Rustin, P., 2013, In: PLoS Genetics. 9, 1, p. e1003182 e1003182.Research output: Contribution to journal › Article › Scientific › peer-review
89 Citations (Scopus) -
The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling
Sullivan, L. B., Martinez-Garcia, E., Nguyen, H., Mullen, A. R., Dufour, E., Sudarshan, S., Licht, J. D., Deberardinis, R. J. & Chandel, N. S., 2013, In: MOLECULAR CELL. 51, 2, p. 236-48Research output: Contribution to journal › Article › Scientific › peer-review
203 Citations (Scopus) -
2012
Glucose modulates respiratory complex I activity in response to acute mitochondrial dysfunction.
Cannino, G., El-Khoury, R., Pirinen, M., Hutz, B., Rustin, P., Jacobs, H. T. & Dufour, E., 2012, In: Journal of Biological Chemistry. 287, 46, p. 38729-38740Research output: Contribution to journal › Article › Scientific › peer-review
39 Citations (Scopus) -
2010
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
Sanz, A., Soikkeli, M., Portero-Otín, M., Wilson, A., Kemppainen, E., McIlroy, G., Ellilä, S., Kemppainen, K., Tuomela, T., Lakanmaa, M., Kiviranta, E., Stefanatos, R., Dufour, E., Hutz, B., Naudí, A., Jové, M., Zeb, A., Vartiainen, S., Matsuno-Yagi, A. & Yagi, T. & 4 others, , 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 20, p. 9105-9110Research output: Contribution to journal › Article › Scientific › peer-review
118 Citations (Scopus) -
2009
Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells
Dassa, E., Dufour, E., Goncalves, S., Paupe, V., Hakkaart, G., Jacobs, H. & Rustin, P., 2009, In: EMBO Molecular Medicine. 1, 1, p. 30-36Research output: Contribution to journal › Article › Scientific › peer-review
82 Citations (Scopus) -
The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells
Dassa, E., Dufour, E., Goncalves, S., Jacobs, H. & Rustin, P., 2009, In: PHYSIOLOGIA PLANTARUM. 137, 4, p. 427-434Research output: Contribution to journal › Article › Scientific › peer-review
29 Citations (Scopus) -
2005
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
Trifunovic, A., Hansson, A., Wnberg, A., Wredenberg, A., Rovio, A., Dufour, E., Khvorostov, I., Spelbrink, J., Wibom, R., Jacobs, H. & Larsson, N., 2005, In: Proc Natl Acad Sci USA. 102, 50, p. 17993-17998Research output: Contribution to journal › Article › Scientific › peer-review
457 Citations (Scopus)