Leo-Pekka Lyytikäinen

2025

Polygenic risk for schizophrenia and subjective well-being in a general population sample

Serimaa, O., Keltikangas-Järvinen, L., Lyytikäinen, L.-P., Hietala, J., Sormunen, E., Kähönen, M., Raitakari, O., Lehtimäki, T. & Saarinen, A., 2 May 2025, In: Psychological Medicine. 55, e133.

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Polygenic risk for schizophrenia predicting Big Five personality traits in individuals without non-affective psychosis

Lavonius, V., Keltikangas-Järvinen, L., Lyytikäinen, L. P., Hamal Mishra, B., Sormunen, E., Kähönen, M., Raitakari, O., Hietala, J., Lehtimäki, T. & Saarinen, A., Jul 2025, In: SCHIZOPHRENIA RESEARCH. 281, p. 229-236

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Repeated heart rate variability monitoring after myocardial infraction: Cohort profile of the MI-ECG study

Pukkila, T., Rankinen, J., Lyytikäinen, L. P., Oksala, N., Nikus, K., Räsänen, E. & Hernesniemi, J., Apr 2025, In: IJC Heart and Vasculature. 57, 101619.

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2024

Accumulation of Lewy-Related Pathology Starts in Middle Age: The Tampere Sudden Death Study

Kok, E. H., Paetau, A., Martiskainen, M., Lyytikäinen, L. P., Lehtimäki, T., Karhunen, P. & Myllykangas, L., May 2024, In: ANNALS OF NEUROLOGY. 95, 5, p. 843-848 6 p.

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2 Citations (Scopus)

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Early resilience and epigenetic ageing: Results from the prospective Young Finns Study with a 31-year follow-up

Aino, S., Saara, M., Mishra, Pashupati, P., Leo-Pekka, L., Binisha, H. M., Emma, R., Nina, M., Mika, K., Olli, R., Terho, L. & Liisa, K. J., 2024, (E-pub ahead of print) In: AGING CELL.

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Genetic risk score for coronary artery calcification and its predictive ability for coronary artery disease

Mishra, P. P., Mishra, B. H., Lyytikäinen, L. P., Goebeler, S., Martiskainen, M., Hakamaa, E., Kleber, M. E., Delgado, G. E., März, W., Kähönen, M., Karhunen, P. J. & Lehtimäki, T., Dec 2024, In: American Journal of Preventive Cardiology. 20, 8 p., 100884.

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Genetic Risk Scores Associated with Temperament Clusters in Finnish Depression Patients

Salminen, S.-P., Solismaa, A., Lyytikäinen, L.-P., Paavonen, V., Mononen, N., Lehtimäki, T., Leinonen, E. & Kampman, O., 2024, In: ACTA NEUROPSYCHIATRICA. 36, 1, p. 51-59 9 p.

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Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns

Ciantar, J., Marttila, S., Rajić, S., Kostiniuk, D., Mishra, P. P., Lyytikäinen, L. P., Mononen, N., Kleber, M. E., März, W., Kähönen, M., Raitakari, O., Lehtimäki, T. & Raitoharju, E., 2024, In: EPIGENETICS. 19, 1, 19 p., 2397297.

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Leptin and leptin receptor gene polymorphisms and depression treatment response

Tavast, I.-M., Solismaa, A., Lyytikäinen, L. P., Mononen, N., Moilanen, E., Hämäläinen, M., Lehtimäki, T. & Kampman, O., 2024, (E-pub ahead of print) In: ACTA NEUROPSYCHIATRICA. p. 1-8

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Polygenic risk for schizophrenia, social dispositions, and pace of epigenetic aging: Results from the Young Finns Study

Saarinen, A., Marttila, S., Mishra, P. P., Lyytikäinen, L.-P., Raitoharju, E., Mononen, N., Sormunen, E., Kähönen, M., Raitakari, O., Hietala, J., Keltikangas-Järvinen, L. & Lehtimäki, T., Mar 2024, In: AGING CELL. 23, 3, e14052.

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4 Citations (Scopus)

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Polygenic risk for schizophrenia predicting social trajectories in a general population sample

Saarinen, A., Hietala, J., Lyytikäinen, L.-P., Hamal Mishra, B., Sormunen, E., Lavonius, V., Kähönen, M., Raitakari, O., Lehtimäki, T. & Keltikangas-Järvinen, L., 2024, In: Psychological Medicine. 54, p. 1589-1597

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4 Citations (Scopus)

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Polymorphisms in ERBB4 and TACR1 associated with dry mouth in clozapine-treated patients

Puolakka, H., Solismaa, A., Lyytikäinen, L. P., Viikki, M., Seppälä, N., Mononen, N., Lehtimäki, T. & Kampman, O., Apr 2024, (E-pub ahead of print) In: ACTA NEUROPSYCHIATRICA.

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Predicting long-term risk of sudden cardiac death with automatic computer-interpretations of electrocardiogram

Järvensivu-Koivunen, M., Kallonen, A., van Gils, M., Lyytikäinen, L. P., Tynkkynen, J. & Hernesniemi, J., 2024, In: Frontiers in Cardiovascular Medicine. 11, 12 p., 1439069.

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Prediction of Sudden Cardiac Death With Ultra-Short-Term Heart Rate Fluctuations

Hernesniemi, J. A., Pukkila, T., Molkkari, M., Nikus, K., Lyytikäinen, L.-P., Lehtimäki, T., Viik, J., Kähönen, M. & Räsänen, E., Sept 2024, In: JACC: Clinical Electrophysiology. 10, 9, p. 2010-2020

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The association between GRACE score at admission for myocardial infarction and the incidence of sudden cardiac arrests in long-term follow-up–the MADDEC study

Hautamäki, M., Järvensivu-Koivunen, M., Lyytikäinen, L. P., Eskola, M., Lehtimäki, T., Nikus, K., Oksala, N., Tynkkynen, J. & Hernesniemi, J., 24 Mar 2024, In: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 58, 1, 2335905.

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3 Citations (Scopus)

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Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

Early Growth Genetics Consortium, Bradfield, J. P., Kember, R. L., Ulrich, A., Balkiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J. F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J. J., Íñiguez, C. & Kobes, S. & 31 others, Leinonen, J., Lowry, E., Lyytikainen, L. P., Mahajan, A., Pitkänen, N., Schnurr, T. M., Have, C. T., Strachan, D. P., Thiering, E., Vogelezang, S., Wade, K. H., Wang, C. A., Wong, A., Holm, L. A., Chesi, A., Choong, C., Cruz, M., Elliott, P., Franks, S., Frithioff-Bøjsøe, C., Gauderman, W. J., Glessner, J. T., Gilsanz, V., Griesman, K., Hanson, R. L., Kähönen, M., Mononen, N., Eriksson, J. G., Lehtimäki, T., Mykkänen, J. & Shepherd, J. A., 16 Jan 2024, In: Genome biology. 25, 1, 22.

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9 Citations (Scopus)

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X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

Scholz, M., Horn, K., Pott, J., Wuttke, M., Kühnapfel, A., Nasr, M. K., Kirsten, H., Li, Y., Hoppmann, A., Gorski, M., Ghasemi, S., Li, M., Tin, A., Chai, J.-F., Cocca, M., Wang, J., Nutile, T., Akiyama, M., Åsvold, B. O. & Bansal, N. & 139 others, Biggs, M. L., Boutin, T., Brenner, H., Brumpton, B., Burkhardt, R., Cai, J., Campbell, A., Campbell, H., Chalmers, J., Chasman, D. I., Chee, M. L., Chee, M. L., Chen, X., Cheng, C.-Y., Cifkova, R., Daviglus, M., Delgado, G., Dittrich, K., Edwards, T. L., Endlich, K., Michael Gaziano, J., Giri, A., Giulianini, F., Gordon, S. D., Gudbjartsson, D. F., Hallan, S., Hamet, P., Hartman, C. A., Hayward, C., Heid, I. M., Hellwege, J. N., Holleczek, B., Holm, H., Hutri-Kähönen, N., Hveem, K., Isermann, B., Jonas, J. B., Joshi, P. K., Kamatani, Y., Kanai, M., Kastarinen, M., Khor, C. C., Kiess, W., Kleber, M. E., Körner, A., Kovacs, P., Krajcoviechova, A., Kramer, H., Krämer, B. K., Kuokkanen, M., Kähönen, M., Lange, L. A., Lash, J. P., Lehtimäki, T., Li, H., Lin, B. M., Liu, J., Loeffler, M., Lyytikäinen, L.-P., Magnusson, P. K. E., Martin, N. G., Matsuda, K., Milaneschi, Y., Mishra, P. P., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Mychaleckyj, J. C., März, W., Nauck, M., Nikus, K., Nolte, I. M., Noordam, R., Okada, Y., Olafsson, I., Oldehinkel, A. J., Penninx, B. W. J. H., Perola, M., Pirastu, N., Polasek, O., Porteous, D. J., Poulain, T., Psaty, B. M., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rasheed, H., Reilly, D. F., Rice, K. M., Richmond, A., Ridker, P. M., Rotter, J. I., Rudan, I., Sabanayagam, C., Salomaa, V., Schneiderman, N., Schöttker, B., Sims, M., Snieder, H., Stark, K. J., Stefansson, K., Stocker, H., Stumvoll, M., Sulem, P., Sveinbjornsson, G., Svensson, P. O., Tai, E.-S., Taylor, K. D., Tayo, B. O., Teren, A., Tham, Y.-C., Thiery, J., Thio, C. H. L., Thomas, L. F., Tremblay, J., Tönjes, A., van der Most, P. J., Vitart, V., Völker, U., Wang, Y. X., Wang, C., Wei, W. B., Whitfield, J. B., Wild, S. H., Wilson, J. F., Winkler, T. W., Wong, T.-Y., Woodward, M., Sim, X., Chu, A. Y., Feitosa, M. F., Thorsteinsdottir, U., Hung, A. M., Teumer, A., Franceschini, N., Parsa, A., Köttgen, A., Schlosser, P. & Pattaro, C., 18 Jan 2024, In: Nature Communications. 15, 1, 586.

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2023

Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

de las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C. Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A. & Kolčić, I. & 178 others, Lim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F. C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L.-P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y. D. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C. K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs, D. R., Kavousi, M., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O’Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polašek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y. X., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Völzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C. T., Morrison, A. C., Rotter, J. I. & Fornage, M., 2023, In: Frontiers in Genetics. 14, 16 p., 1235337.

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Genetic insights into resting heart rate and its role in cardiovascular disease

The DCCT/EDIC Research Group, van de Vegte, Y. J., Eppinga, R. N., van der Ende, M. Y., Hagemeijer, Y. P., Mahendran, Y., Salfati, E., Smith, A. V., Tan, V. Y., Arking, D. E., Ntalla, I., Appel, E. V., Schurmann, C., Brody, J. A., Rueedi, R., Polasek, O., Sveinbjornsson, G., Lecoeur, C., Ladenvall, C. & Zhao, J. H. & 31 others, Isaacs, A., Wang, L., Luan, J., Hwang, S. J., Mononen, N., Auro, K., Jackson, A. U., Bielak, L. F., Zeng, L., Shah, N., Nethander, M., Campbell, A., Rankinen, T., Pechlivanis, S., Qi, L., Zhao, W., Rizzi, F., Tanaka, T., Robino, A., Cocca, M., Lange, L., Müller-Nurasyid, M., Roselli, C., Zhang, W., Kleber, M. E., Guo, X., Lyytikäinen, L. P., Nikus, K., Kähönen, M., Eriksson, J. G. & Lehtimäki, T., Aug 2023, In: Nature Communications. 14, 21 p., 4646.

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Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

Kavousi, M., Bos, M. M., Barnes, H. J., Lino Cardenas, C. L., Wong, D., Lu, H., Hodonsky, C. J., Landsmeer, L. P. L., Turner, A. W., Kho, M., Hasbani, N. R., de Vries, P. S., Bowden, D. W., Chopade, S., Deelen, J., Benavente, E. D., Guo, X., Hofer, E., Hwang, S. J. & Lutz, S. M. & 69 others, Lyytikäinen, L. P., Slenders, L., Smith, A. V., Stanislawski, M. A., van Setten, J., Wong, Q., Yanek, L. R., Becker, D. M., Beekman, M., Budoff, M. J., Feitosa, M. F., Finan, C., Hilliard, A. T., Kardia, S. L. R., Kovacic, J. C., Kral, B. G., Langefeld, C. D., Launer, L. J., Malik, S., Hoesein, F. A. A. M., Mokry, M., Schmidt, R., Smith, J. A., Taylor, K. D., Terry, J. G., van der Grond, J., van Meurs, J., Vliegenthart, R., Xu, J., Young, K. A., Zilhão, N. R., Zweiker, R., Assimes, T. L., Becker, L. C., Bos, D., Carr, J. J., Cupples, L. A., de Kleijn, D. P. V., de Winther, M., den Ruijter, H. M., Fornage, M., Freedman, B. I., Gudnason, V., Hingorani, A. D., Hokanson, J. E., Ikram, M. A., Išgum, I., Jacobs, D. R., Kähönen, M., Lange, L. A., Lehtimäki, T., Pasterkamp, G., Raitakari, O. T., Schmidt, H., Slagboom, P. E., Uitterlinden, A. G., Vernooij, M. W., Bis, J. C., Franceschini, N., Psaty, B. M., Post, W. S., Rotter, J. I., Björkegren, J. L. M., O’Donnell, C. J., Bielak, L. F., Peyser, P. A., Malhotra, R., van der Laan, S. W. & Miller, C. L., 2023, In: Nature Genetics. 55, 10, p. 1651-1664 14 p.

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40 Citations (Scopus)

Polygenic liabilities underlying job stress and exhaustion over a 10-year follow-up: A general population study

Saarinen, A., Hietala, J., Lyytikäinen, L. P., Hamal Mishra, B., Sormunen, E., Kähönen, M., Rovio, S., Viikari, J., Raitakari, O., Lehtimäki, T. & Keltikangas-Järvinen, L., Aug 2023, In: PSYCHIATRY RESEARCH. 326, 115355.

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Rare variant analyses across multiethnic cohorts identify novel genes for refractive error

Musolf, A. M., Haarman, A. E. G., Luben, R. N., Ong, J. S., Patasova, K., Trapero, R. H., Marsh, J., Jain, I., Jain, R., Wang, P. Z., Lewis, D. D., Tedja, M. S., Li, H., Cowan, C. S., Consortium for Refractive Error and Myopia (CREAM), Biino, G., Klein, A. P., Duggal, P., Mackey, D. A. & Hayward, C. & 15 others, Haller, T., Metspalu, A., Wedenoja, J., Pärssinen, O., Ching-Yu, C., Saw, S. M., Stambolian, D., Hysi, P. G., Khawaja, A. P., Vitart, V., Hammond, C. J., van Dujin, C. M., Verhoeven, V. J. M., Klaver, C. C. W. & Bailey-Wilson, J. E., Jan 2023, In: Communications biology. 6, 6.

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4 Citations (Scopus)

Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods

Lehtimäki, M., H. Mishra, B., Del-Val, C., Lyytikäinen, L. P., Kähönen, M., Cloninger, C. R., Raitakari, O. T., Laaksonen, R., Zwir, I., Lehtimäki, T. & Mishra, P. P., Feb 2023, In: Scientific Reports. 13, 1, 3078.

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2022

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Million Veterans Program, Global Lipids Genetics Consortium, Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H. & Ntalla, I. & 32 others, Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Rosenthal, E. A., Hutri-Kähönen, N., Lyytikäinen, L. P., Nikus, K., Kovacs, P., Kähönen, M., Lehtimäki, T., Tuomilehto, J., Kuusisto, J. & Abbas, S., 4 Aug 2022, In: AMERICAN JOURNAL OF HUMAN GENETICS. 109, 8, p. 1366-1387 22 p.

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A saturated map of common genetic variants associated with human height

23andMe Research Team, VA Million Veteran Program, DiscovEHR (DiscovEHR and MyCode Community Health Initiative), eMERGE (Electronic Medical Records and Genomics Network), Lifelines cohort study, The PRACTICAL Consortium, Understanding Society Scientific Group, Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D. & Graham, S. E. & 37 others, Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S. H., Ferreira, T., Highland, H. H., Ji, Y., Karaderi, T., Lin, K., Lüll, K., Malden, D. E., Medina-Gomez, C., Machado, M., Moore, A., Rüeger, S., Sim, X., Vrieze, S., Ahluwalia, T. S., Akiyama, M., Allison, M. A., Alvarez, M., Andersen, M. K., Ani, A., Appadurai, V., Arbeeva, L., Bhaskar, S., Bielak, L. F., Bollepalli, S., Bonnycastle, L. L., Bork-Jensen, J., Bradfield, J. P., Hansen, T. F., Lyytikäinen, L. P., Mishra, P. P., Kähönen, M., Lehtimäki, T. & Tuomilehto, J., 2022, In: Nature. 610, p. 704–712 9 p.

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356 Citations (Scopus)

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Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis

Schillemans, T., Tragante, V., Maitusong, B., Gigante, B., Cresci, S., Laguzzi, F., Vikström, M., Richards, M., Pilbrow, A., Cameron, V., Foco, L., Doughty, R. N., Kuukasjärvi, P., Allayee, H., Hartiala, J. A., Tang, W. H. W., Lyytikäinen, L. P., Nikus, K., Laurikka, J. O. & Srinivasan, S. & 37 others, Mordi, I. R., Trompet, S., Kraaijeveld, A., van Setten, J., Gijsberts, C. M., Maitland-van der Zee, A. H., Saely, C. H., Gong, Y., Johnson, J. A., Cooper-DeHoff, R. M., Pepine, C. J., Casu, G., Leiherer, A., Drexel, H., Horne, B. D., van der Laan, S. W., Marziliano, N., Hazen, S. L., Sinisalo, J., Kähönen, M., Lehtimäki, T., Lang, C. C., Burkhardt, R., Scholz, M., Jukema, J. W., Eriksson, N., Åkerblom, A., James, S., Held, C., Hagström, E., Spertus, J. A., Algra, A., de Faire, U., Åkesson, A., Asselbergs, F. W., Patel, R. S. & Leander, K., 23 Jun 2022, In: Frontiers in Physiology. 13, 14 p., 909870.

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C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

Park, I., Goddard, M. E., Cole, J. E., Zanin, N., Lyytikäinen, L.-P., Lehtimäki, T., Andreakos, E., Feldmann, M., Udalova, I., Drozdov, I. & Monaco, C., 11 Jan 2022, In: Nature Communications. 13, 17 p., 215.

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Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Lifelines cohort study, DiscovEHR/MyCode study, VA Million Veteran Program, Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J. F., Sieber, K. B., Horn, K. & Li, M. & 33 others, Scholz, M., Cocca, M., Wuttke, M., van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Kuusisto, J., Nikus, K., Lyytikäinen, L. P., Kähönen, M., Hutri-Kähönen, N., Mononen, N., Mishra, P. P., Kovacs, P. & Lehtimäki, T., Jun 2022, In: Communications biology. 5, 20 p., 580.

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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T. V., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J. W., Haessler, J., Lyytikäinen, L. P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P. & Evans, D. S. & 146 others, Freudling, R., Hines, O., Isaksen, J. L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, C., Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, G., Alonso, A., Andreasen, L., Bis, J. C., Boerwinkle, E., Campbell, A., Catamo, E., Cocca, M., Cutler, M. J., Darbar, D., De Grandi, A., De Luca, A., Ding, J., Ellervik, C., Ellinor, P. T., Felix, S. B., Froguel, P., Fuchsberger, C., Gögele, M., Graff, C., Graff, M., Guo, X., Hansen, T., Heckbert, S. R., Huang, P. L., Huikuri, H. V., Hutri-Kähönen, N., Ikram, M. A., Jackson, R. D., Junttila, J., Kavousi, M., Kors, J. A., Leal, T. P., Lemaitre, R. N., Lin, H. J., Lind, L., Linneberg, A., Liu, S., MacFarlane, P. W., Mangino, M., Meitinger, T., Mezzavilla, M., Mishra, P. P., Mitchell, R. N., Mononen, N., Montasser, M. E., Morrison, A. C., Nauck, M., Nauffal, V., Navarro, P., Nikus, K., Pare, G., Patton, K. K., Pelliccione, G., Pittman, A., Porteous, D. J., Pramstaller, P. P., Preuss, M. H., Raitakari, O. T., Reiner, A. P., Ribeiro, A. L. P., Rice, K. M., Risch, L., Schlessinger, D., Schotten, U., Schurmann, C., Shen, X., Shoemaker, M. B., Sinagra, G., Sinner, M. F., Soliman, E. Z., Stoll, M., Strauch, K., Tarasov, K., Taylor, K. D., Tinker, A., Trompet, S., Uitterlinden, A., Völker, U., Völzke, H., Waldenberger, M., Weng, L. C., Whitsel, E. A., Wilson, J. G., Avery, C. L., Conen, D., Correa, A., Cucca, F., Dörr, M., Gharib, S. A., Girotto, G., Grarup, N., Hayward, C., Jamshidi, Y., Järvelin, M. R., Jukema, J. W., Kääb, S., Kähönen, M., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lima-Costa, M. F., Liu, Y., Loos, R. J. F., Lubitz, S. A., Mook-Kanamori, D. O., Morris, A. P., O'Connell, J. R., Olesen, M. S., Orini, M., Padmanabhan, S., Pattaro, C., Peters, A., Psaty, B. M., Rotter, J. I., Stricker, B., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. F., Arking, D. E., Ramirez, J., Lambiase, P. D., Sotoodehnia, N., Mifsud, B., Newton-Cheh, C. & Munroe, P. B., Sept 2022, In: Nature Communications. 13, 18 p., 5144.

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Günther, F., Stark, K. J., Chai, J. F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Ärnlöv, J., Åsvold, B. O., Bakker, S. J. L., Banas, B. & Bansal, N. & 30 others, Biggs, M. L., Biino, G., Böhnke, M., Boerwinkle, E., Bottinger, E. P., Brenner, H., Brumpton, B., Carroll, R. J., Chaker, L., Chalmers, J., Chee, M. L., Chee, M. L., Cheng, C. Y., Chu, A. Y., Ciullo, M., Cocca, M., Cook, J. P., Coresh, J., Cusi, D., de Borst, M. H., Degenhardt, F., Eckardt, K. U., Hutri-Kähönen, N., Kähönen, M., Kuusisto, J., Lehtimäki, T., Lyytikäinen, L. P., Mishra, P. P., Mononen, N. & Nikus, K., 2022, In: KIDNEY INTERNATIONAL. 102, 3, p. 624-639 16 p.

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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Lifelines cohort study, Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E. & Feenstra, B. & 31 others, Feitosa, M. F., Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, Å., Jørgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Lagou, V., Lind, P. A., Lorentzon, M., Lyytikäinen, L. P., Mangino, M., Metzendorf, C., Monroe, K. R., Pacolet, A., Pérusse, L., Kähönen, M., Kuusisto, J. & Lehtimäki, T., 2022, In: Nature Genetics. 54, p. 1332-1344 13 p.

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High-risk ECG patterns in ST elevation myocardial infarction for mortality prediction

Lahti, R., Rankinen, J., Lyytikäinen, L. P., Eskola, M., Nikus, K. & Hernesniemi, J., 2022, In: Journal of Electrocardiology. 74, p. 13-19 7 p.

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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K.-H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z. & Xue, C. & 519 others, Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Rosenthal, E. A., Lingren, T., Feng, Q., Kullo, I. J., Narita, A., Takayama, J., Martin, H. C., Hunt, K. A., Trivedi, B., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Rasheed, A., Hindy, G., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Choudhury, A., Sengupta, D., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J.-H., Matsuda, F., Jang, H.-M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Yousri, N. A., Mitchell, R. E., Chai, J. F., Aadahl, M., Bjerregaard, A. A., Yao, J., Manichaikul, A., Hwu, C.-M., Hung, Y.-J., Warren, H. R., Ramirez, J., Bork-Jensen, J., Kårhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Mauro, P., Matteo, F., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, L. T., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Ruotsalainen, S. E., Daw, E., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Vazquez-Moreno, M., Feitosa, M. F., Wojczynski, M. K., Wang, Z., Preuss, M. H., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Tsao, N. L., Verma, A., Slieker, R. C., Lo, K. S., Zilhao, N. R., Le, P., Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Demirkan, A., Leonard, H. L., Marten, J., Frank, M., Schmidt, B., Smyth, L. J., Cañadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kähönen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Nongmaithem, S. S., Bayyana, S., Stringham, H. M., Irvin, M. R., Oldmeadow, C., Kim, H.-N., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Prasad, G., Lorés-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Banas, B., Nardone, G. G., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A.-E., Hofer, E., Lin, M., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkänen, N., Cade, B. E., van der Laan, S. W., Chitrala, K. N., Weiss, S., Bentley, A. R., Doumatey, A. P., Adeyemo, A. A., Lee, J. Y., Petersen, E. R. B., Nielsen, A. A., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S.-Y., Wang, J.-S., Couture, C., Lyytikäinen, L.-P., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hidalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Liang, J., Tang, H., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Kawaguchi, T., Thiery, J., Bis, J. C., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jäger, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X.-O., Rallidis, L. S., Pedersen, O., Hansen, T., Mitchell, P., Hewitt, A. W., Kähönen, M., Pérusse, L., Bouchard, C., Tönjes, A., Chen, Y.-D. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellström, D., Cho, Y. S., Lee, H., Yuan, J.-M., Koh, W.-P., Rhee, S. Y., Woo, J.-T., Heid, I. M., Stark, K. J., Zimmermann, M. E., Völzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Peyser, P. A., Kato, N., Schulze, M. B., Girotto, G., Böger, C. A., Jung, B., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Tusié-Luna, T., Aguilar-Salinas, C. A., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J.-Y., Zheng, W., Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C.-K., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H.-L., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Hunt, S. C., Walker, M., Koistinen, H. A., Chandak, G. R., Mercader, J. M., Costanzo, M. C., Jang, D., Burtt, N. P., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E., van Dam, R. M., Lehtimäki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jöckel, K.-H., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Jin, Z.-B., Qu, J., Hishigaki, H., Lin, X., März, W., Gudnason, V., Tardif, J.-C., Lettre, G., Hart, L. M. '., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Parra, E. J., Cruz, M., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Rotimi, C. N., Christensen, K., Ripatti, S., Widén, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, A., Jukema, J. W., Khera, A. V., Männikkö, M., Jarvelin, M.-R., Kutalik, Z., Francesco, C., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, N., Sever, P., Poulter, N., Chuang, L.-M., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C.-Y., Wong, T.-Y., Khor, C. C., Li, H., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., Willemsen, A. H. M., Cupples, L., van Meurs, J. B. J., Ghanbari, M., Gordon-Larsen, P., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., Hazelhurst, S., Ramsay, M., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Baras, A., Justice, A. E., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Tamiya, G., Yamamoto, M., van Heel, D. A., Trembath, R. C., Wei, W.-Q., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Åsvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Kim, B.-J., Thorsteinsdottir, U., Stefansson, K., Zhang, J., Chen, Y., Ho, Y.-L., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K.-M., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P. W. F., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Mohlke, K. L., Sun, Y. V., Morris, A. P., Boehnke, M., Brown, C. D., Natarajan, P., Deloukas, P., Willer, C. J., Assimes, T. L. & Peloso, G. M., 27 Dec 2022, In: Genome Biology. 23, 1, 42 p., 268.

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Interatrial block and P terminal force in the general population: Longitudinal changes, risk factors and prognosis

Istolahti, T., Eranti, A., Huhtala, H., Tynkkynen, J., Lyytikäinen, L. P., Kähönen, M., Lehtimäki, T., Eskola, M., Anttila, I., Jula, A., Nikus, K. & Hernesniemi, J., 2022, In: Journal of Electrocardiology. 73, p. 12-20 9 p.

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Long-term tracking and population characteristics of lipoprotein (a) in the Cardiovascular Risk in Young Finns Study

Raitakari, O., Kivelä, A., Pahkala, K., Rovio, S., Mykkänen, J., Ahola-Olli, A., Loo, B. M., Lyytikäinen, L. P., Lehtimäki, T., Kähönen, M., Juonala, M., Rönnemaa, T., Lamina, C., Kronenberg, F. & Viikari, J., Sept 2022, In: Atherosclerosis. 356, p. 18-27 10 p.

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Magical thinking in individuals with high polygenic risk for schizophrenia but no non-affective psychoses: a general population study

Saarinen, A., Lyytikäinen, L. P., Hietala, J., Dobewall, H., Lavonius, V., Raitakari, O., Kähönen, M., Sormunen, E., Lehtimäki, T. & Keltikangas-Järvinen, L., 2022, In: MOLECULAR PSYCHIATRY. 27, 8, p. 3286–3293 8 p.

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Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci

Laaksonen, J., Mishra, P. P., Seppälä, I., Raitoharju, E., Marttila, S., Mononen, N., Lyytikäinen, L.-P., Kleber, M. E., Delgado, G. E., Lepistö, M., Almusa, H., Ellonen, P., Lorkowski, S., März, W., Hutri-Kähönen, N., Raitakari, O., Kähönen, M., Salonen, J. T. & Lehtimäki, T., 2022, In: Human Molecular Genetics. 31, 10, p. 1720–1732

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Prevalence and long-term prognostic implications of prolonged QRS duration in left ventricular hypertrophy: a population-based observational cohort study

Rankinen, J., Haataja, P., Lyytikäinen, L. P., Huhtala, H., Lehtimäki, T., Kähönen, M., Eskola, M., Tuohinen, S., Pérez-Riera, A. R., Jula, A., Rissanen, H., Nikus, K. & Hernesniemi, J., 28 Feb 2022, In: BMJ Open. 12, 8 p., e053477.

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The S1S2S3 electrocardiographic pattern — Prevalence and relation to cardiovascular and pulmonary diseases in the general population

Nurminen, J., Pérez-Riera, A. R., de Luna, A. B., Nikus, K., Lyytikäinen, L. P., Huhtala, H., Eskola, M., Kähönen, M., Jula, A., Lehtimäki, T. & Hernesniemi, J., Jul 2022, In: Journal of Electrocardiology. 73, p. 113-119 7 p.

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Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

Marttila, S., Rovio, S., Mishra, P. P., Seppälä, I., Lyytikäinen, L. P., Juonala, M., Waldenberger, M., Oksala, N., Ala-Korpela, M., Harville, E., Hutri-Kähönen, N., Kähönen, M., Raitakari, O., Lehtimäki, T. & Raitoharju, E., Apr 2021, In: Scientific Reports. 11, 1, 9203.

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Assessment of plasma ceramides as predictor for subclinical atherosclerosis

Mishra, P. P., Mishra, B. H., Lyytikäinen, L. P., Hilvo, M., Juonala, M., Kähönen, M., Hutri-Kähönen, N., Fotiadis, D. I., Raitakari, O. T., Laaksonen, R. & Lehtimäki, T., Nov 2021, In: Atherosclerosis Plus. 45, p. 25-31 7 p.

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Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts

Laaksonen, J., Mishra, P. P., Seppälä, I., Lyytikäinen, L.-P., Raitoharju, E., Mononen, N., Lepistö, M., Almusa, H., Ellonen, P., Hutri-Kähönen, N., Juonala, M., Raitakari, O., Kähönen, M., Salonen, J. T. & Lehtimäki, T., 2021, In: Scientific Reports. 11, 1, 611.

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Functional Polymorphisms in Oxytocin and Dopamine Pathway Genes and the Development of Dispositional Compassion Over Time: The Young Finns Study

Dobewall, H., Saarinen, A., Lyytikäinen, L. P., Keltikangas-Järvinen, L., Lehtimäki, T. & Hintsanen, M., 2021, In: Frontiers in Psychology. 12, 576346.

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Genetic differential susceptibility to the parent–child relationship quality and the life span development of compassion

Dobewall, H., Keltikangas-Järvinen, L., Saarinen, A., Lyytikäinen, L. P., Zwir, I., Cloninger, R., Raitakari, O. T., Lehtimäki, T. & Hintsanen, M., 2021, In: DEVELOPMENTAL PSYCHOBIOLOGY. 63, 6, e22184.

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Genome-wide analysis identifies novel susceptibility loci for myocardial infarction

Hartiala, J. A., Han, Y., Jia, Q., Hilser, J. R., Huang, P., Gukasyan, J., Schwartzman, W. S., Cai, Z., Biswas, S., Trégouët, D. A., Smith, N. L., INVENT Consortium, CHARGE Consortium Hemostasis Working Group, GENIUS-CHD Consortium, Seldin, M., Pan, C., Mehrabian, M., Lusis, A. J., Bazeley, P. & Sun, Y. V. & 34 others, Liu, C., Quyyumi, A. A., Scholz, M., Thiery, J., Delgado, G. E., Kleber, M. E., März, W., Howe, L. J., Asselbergs, F. W., van Vugt, M., Vlachojannis, G. J., Patel, R. S., Lyytikäinen, L. P., Kähönen, M., Lehtimäki, T., Nieminen, T. V. M., Kuukasjärvi, P., Laurikka, J. O., Chang, X., Heng, C. K., Jiang, R., Kraus, W. E., Hauser, E. R., Ferguson, J. F., Reilly, M. P., Ito, K., Koyama, S., Kamatani, Y., Komuro, I., Biobank Japan, Stolze, L. K., Romanoski, C. E., Khan, M. D. & Turner, A. W., 2021, In: European Heart Journal. 42, 9, p. 919-933 15 p.

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Impedance plethysmography-based method in the assessment of subclinical atherosclerosis

Haapala, M., Lyytikäinen, L.-P., Peltokangas, M., Koivistoinen, T., Hutri-Kähönen, N., Laurila, M.-M., Mäntysalo, M., Raitakari, O. T., Kähönen, M., Lehtimäki, T., Vehkaoja, A. & Oksala, N., 2021, In: Atherosclerosis. 319, p. 101-107 7 p.

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Long-term outcome of intraventricular conduction delays in the general population

Rankinen, J., Haataja, P., Lyytikäinen, L.-P., Huhtala, H., Lehtimäki, T., Kähönen, M., Eskola, M., Pérez-Riera, A. R., Jula, A., Rissanen, H., Nikus, K. & Hernesniemi, J., 2021, In: ANNALS OF NONINVASIVE ELECTROCARDIOLOGY. 26, 1, e12788.

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

Lifelines cohort study, Gorski, M., Jung, B., Li, Y., Matias-Garcia, P. R., Wuttke, M., Coassin, S., Thio, C. H. L., Kleber, M. E., Winkler, T. W., Wanner, V., Chai, J.-F., Chu, A. Y., Cocca, M., Feitosa, M. F., Ghasemi, S., Hoppmann, A., Horn, K., Li, M. & Nutile, T. & 31 others, Scholz, M., Sieber, K. B., Teumer, A., Tin, A., Wang, J., Tayo, B. O., Ahluwalia, T. S., Almgren, P., Bakker, S. J. L., Banas, B., Bansal, N., Biggs, M. L., Boerwinkle, E., Bottinger, E. P., Brenner, H., Carroll, R. J., Chalmers, J., Chee, M.-L., Chee, M.-L., Cheng, C.-Y., Coresh, J., de Borst, M. H., Degenhardt, F., Eckardt, K.-U., Hutri-Kähönen, N., Kähönen, M., Lehtimäki, T., Lyytikäinen, L.-P., Mishra, P. P., Mononen, N. & Nikus, K., 1 Apr 2021, In: KIDNEY INTERNATIONAL. 99, 4, p. 926-939

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Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs

Marttila, S., Viiri, L. E., Mishra, P. P., Kühnel, B., Matias-Garcia, P. R., Lyytikäinen, L. P., Ceder, T., Mononen, N., Rathmann, W., Winkelmann, J., Peters, A., Kähönen, M., Hutri-Kähönen, N., Juonala, M., Aalto-Setälä, K., Raitakari, O., Lehtimäki, T., Waldenberger, M. & Raitoharju, E., Jul 2021, In: Clinical Epigenetics. 13, 143.

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Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

Lifelines cohort study, Sun, D., Richard, M. A., Musani, S. K., Sung, Y. J., Winkler, T. W., Schwander, K., Chai, J. F., Guo, X., Kilpeläinen, T. O., Vojinovic, D., Aschard, H., Bartz, T. M., Bielak, L. F., Brown, M. R., Chitrala, K., Hartwig, F. P., Horimoto, A. R. V. R., Liu, Y. & Manning, A. K. & 31 others, Noordam, R., Smith, A. V., Harris, S. E., Kühnel, B., Lyytikäinen, L. P., Nolte, I. M., Rauramaa, R., van der Most, P. J., Wang, R., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Arking, D. E., Arnett, D. K., Barac, A., Boerwinkle, E., Broeckel, U., Chakravarti, A., Chen, Y. D. I., Cupples, L. A., Davigulus, M. L., de las Fuentes, L., de Mutsert, R., de Vries, P. S., Delaney, J. A. C., Diez Roux, A. V., Dörr, M., Faul, J. D., Fretts, A. M. & Lehtimäki, T., 2021, In: Human Genetics and Genomics Advances. 2, 1, 100013.

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Leo-Pekka Lyytikäinen

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