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Anti-Inflammatory and anti-catabolic effects of dexamethasone are mediated through MKP-1 in murine models
T Myyry (Contributor), T Leppänen (Contributor), R Nieminen (Contributor), L Tuure (Contributor) & E Moilanen (Contributor)
13 Feb 2020Activity: Talk or presentation › Conference presentation
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TRPA1 mediates DNCB-induced allergic contact dermatitis
I Mäki-Opas (Contributor), M Hämäläinen (Contributor), LJ Moilanen (Contributor), H Sood (Contributor), T Leppänen (Contributor), L Lehtimäki (Contributor) & E Moilanen (Contributor)
29 Nov 2019Activity: Talk or presentation › Conference presentation
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Anti-inflammatory and anti-catabolic effects of dexamethasone are mediated through MKP-1 in murine models
Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Riina Nieminen (Contributor)
29 Nov 2019Activity: Talk or presentation › Conference presentation
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Comprehensive effects of ibuprofen on gene expression in chondrocytes as determined by RNA-Seq
Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Katriina Vuolteenaho (Contributor)
29 Nov 2019Activity: Talk or presentation › Conference presentation
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Anti-inflammatory mechanisms of PDE4 inhibitors: Rolipram induces macrophage polarization from inflammatory (M1) to healing promoting (M2) phenotype through MKP-1
Tiina Leppänen (Contributor), Mari Hämäläinen (Contributor), Eeva Moilanen (Contributor) & Riina Nieminen (Contributor)
29 Nov 2019Activity: Talk or presentation › Conference presentation
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Anti-inflammatory mechanisms of PDE4 inhibitors: Rolipram induces macrophage polarization from inflammatory (M1) to healing promoting (M2) phenotype through MKP-1 phosphatase
Tiina Leppänen (Contributor), Mari Hämäläinen (Contributor), Eeva Moilanen (Contributor) & Riina Nieminen (Contributor)
15 Sep 2019Activity: Talk or presentation › Conference presentation
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Comprehensive effects of ibuprofen on gene expression in chondrocytes as determined by RNA-Seq
A Pemmari (Contributor), L Tuure (Contributor), M Hämäläinen (Contributor), T Leppänen (Contributor), K Vuolteenaho (Contributor), T Moilanen (Contributor) & E Moilanen (Contributor)
2 May 2019Activity: Talk or presentation › Conference presentation
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CAMP enhancing drugs salbutamol and rolipram augment alternative macrophage activation through MKP-1
T Kivistö (Contributor), M Scotece (Contributor), M Hämäläinen (Contributor) & E Moilanen (Contributor)
20 Mar 2019Activity: Talk or presentation › Conference presentation
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Mitogen-activated protein kinase phosphatase 1 (MKP-1) as a mediator of anti-inflammatory and anti-catabolic effects of dexamethasone
T Myyry (Contributor), T Leppänen (Contributor), R Nieminen (Contributor) & E Moilanen (Contributor)
20 Mar 2019Activity: Talk or presentation › Conference presentation
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Comprehensive effects of ibuprofen on gene expression in chondrocytes as determined by RNA-Seq
Antti Pemmari (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Katriina Vuolteenaho (Contributor)
20 Mar 2019Activity: Talk or presentation › Conference presentation
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Comprehensive effects of ibuprofen on gene expression in chondrocytes as determined by RNA-Seq
A Pemmari (Speaker), L Tuure (Speaker), M Hämäläinen (Speaker), T Leppänen (Speaker), K Vuolteenaho (Speaker), T Moilanen (Speaker) & E Moilanen (Speaker)
24 Jan 2019Activity: Talk or presentation › Conference presentation
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PDE4 inhibitor rolipram augments the alternative activation of murine macrophages through MKP-1
Tiina Leppänen (Speaker), Mari Hämäläinen (Speaker), Eeva Moilanen (Speaker), Tiina Myyry (Speaker) & Riina Nieminen (Speaker)
24 Jan 2019Activity: Talk or presentation › Conference presentation
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The effects of dexamethasone on inflammatory and catabolic factors in chondrocytes are mediated through MKP-1
Tiina Myyry (Speaker), Tiina Leppänen (Speaker), Eeva Moilanen (Speaker) & Riina Nieminen (Speaker)
24 Jan 2019Activity: Talk or presentation › Conference presentation
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IL-6 in osteoarthritis: effects of pinosylvin and monomethyl pinosylvin
M Laavola (Contributor), T Leppänen (Contributor), M Hämäläinen (Contributor), K Vuolteenaho (Contributor), T Moilanen (Contributor), R Nieminen (Contributor) & E Moilanen (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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CAMP enhancing drugs salbutamol and rolipram augment the alternative activation of murine macrophages through MKP-1
Tiina Leppänen (Contributor), Mari Hämäläinen (Contributor) & Eeva Moilanen (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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Gene expression in adverse reaction to metal debris around metal-on-metal arthroplasty: an RNA-Seq-based study
A Pemmari (Speaker), T Penttilä (Speaker), EL Paukkeri (Speaker), A Eskelinen (Speaker), T Moilanen (Speaker) & E Moilanen (Speaker)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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MKP-1 as a novel factor in the pathogenesis of scleroderma. An experimental study
Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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MAP kinase phosphatase-1 (MKP-1) as a target of anti-inflammatory drug treatment: Anti-inflammatory effects of the glucocorticoid dexamethasone are mediated by MKP-1 in murine models
R Nieminen (Contributor), A Pemmari (Contributor), M Hämäläinen (Contributor), T Leppänen (Contributor) & E Moilanen (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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Anti-inflammatory properties of the ?2-receptor agonist salbutamol and the PDE4 inhibitor rolipram are mediated by MKP-1
Mari Hämäläinen (Contributor), Riku Korhonen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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Novel adipokine associated with osteoarthritis: retinol binding protein 4 is produced by cartilage and correlates with matrix metalloproteinases in osteoarthritis patients
Tiina Leppänen (Contributor), Mari Hämäläinen (Contributor), Eeva Moilanen (Contributor) & Katriina Vuolteenaho (Contributor)
23 Nov 2018Activity: Talk or presentation › Conference presentation
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MAP kinase phosphatase-1 (MKP-1) as a target of anti-inflammatory drug treatment: Anti-inflammatory effects of the glucocorticoid dexamethasone are mediated by MKP-1 in murine models
Riina Nieminen (Speaker), Mari Hämäläinen (Speaker), Tiina Leppänen (Speaker) & Eeva Moilanen (Speaker)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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IL-6 in osteoarthritis: effects of pinosylvin and monomethyl pinosylvin
M Laavola (Contributor), T Leppänen (Contributor), M Hämäläinen (Contributor), K Vuolteenaho (Contributor), T Moilanen (Contributor), R Nieminen (Contributor) & E Moilanen (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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Novel adipokine associated with osteoarthritis: retinol binding protein 4 is produced by cartilage and correlates with matrix metalloproteinases in osteoarthritis patients
M Scotece (Contributor), A Koskinen-Kolasa (Contributor), A Pemmari (Contributor), T Leppänen (Contributor), M Hämäläinen (Contributor), T Moilanen (Contributor), E Moilanen (Contributor) & K Vuolteenaho (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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MKP-1 as a novel factor in the pathogenesis of scleroderma. An experimental study
Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by next generation sequencing-based genome wide expression analysis
A Pemmari (Speaker), T Syvänen (Speaker), M Hämäläinen (Speaker), T Moilanen (Speaker), K Vuolteenaho (Speaker) & E Moilanen (Speaker)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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Anti-inflammatory properties of the ?2-receptor agonist salbutamol and the PDE4 inhibitor rolipram are mediated by MKP-1
Mari Hämäläinen (Contributor), Riku Korhonen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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CAMP enhancing drugs salbutamol and rolipram augment the alternative activation of murine macrophages through MKP-1
Tiina Leppänen (Contributor), Mari Mäkinen (Contributor) & Eeva Moilanen (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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Gene expression in adverse reaction to metal debris around metal-on-metal arthroplasty: an RNA-Seq-based study
A Pemmari (Contributor), T Leppänen (Contributor), E-L Paukkeri (Contributor), A Eskelinen (Contributor), T Moilanen (Contributor) & E Moilanen (Contributor)
5 Sep 2018Activity: Talk or presentation › Conference presentation
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Anti-inflammatory properties of the ?2-receptor agonist salbutamol and the PDE4 inhibitor rolipram are mediated by MKP-1
T Keränen (Contributor), T Hömmö (Contributor), M Hämäläinen (Contributor), T Leppänen (Contributor), E Moilanen (Contributor) & R Korhonen (Contributor)
1 Jun 2018Activity: Talk or presentation › Conference presentation
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Gene expression in adverse reaction to metal debris around metal-on metal arthroplasty: an RNA-Seq-based study
Antti Pemmari (Contributor), Tiina Syrjäläinen (Contributor) & Eeva Moilanen (Contributor)
26 Apr 2018Activity: Talk or presentation › Conference presentation
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MKP-1 as a novel factor in the pathogenesis of scleroderma. An experimental study
Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
24 Apr 2018Activity: Talk or presentation › Conference presentation
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MAP kinase phosphatase-1 (MKP-1) as a target of anti-inflammatory drug treatment: Anti-inflammatory effects of the glucocorticoid dexamethasone are mediated by MKP-1 in vitro and in vivo models
R Nieminen (Contributor), A Pemmari (Contributor), M Hämäläinen (Contributor), T Leppänen (Contributor) & E Moilanen (Contributor)
24 Apr 2018Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by next generation sequencing-based genome wide expression analysis
Antti Pemmari (Speaker), Mari Hämäläinen (Speaker), Tiina Leppänen (Speaker), Eeva Moilanen (Speaker) & Katriina Vuolteenaho (Speaker)
24 Apr 2018Activity: Talk or presentation › Conference presentation
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Gene expression in adverse reaction to metal debris around metal-on-metal arthroplasty: an RNA-Seq-based study
A Pemmari (Contributor), T Leppänen (Contributor), EL Paukkeri (Contributor), A Eskelinen (Contributor), T Moilanen (Contributor) & E Moilanen (Contributor)
21 Mar 2018Activity: Talk or presentation › Conference presentation
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Anti-inflammatory properties of the ?2-receptor agonist salbutamol and the PDE4 inhibitor rolipram are mediated by MKP-1
Tiina Keränen (Contributor), Mari Hämäläinen (Contributor), Riku Korhonen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
21 Mar 2018Activity: Talk or presentation › Conference presentation
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IL-6 in osteoarthritis: effects of pinosylvin and monomethyl pinosylvin
M Laavola (Speaker), T Leppänen (Speaker), M Hämäläinen (Speaker), K Vuolteenaho (Speaker), T Moilanen (Speaker), R Nieminen (Speaker) & E Moilanen (Speaker)
25 Jan 2018Activity: Talk or presentation › Conference presentation
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Gene expression in adverse reaction to metal debris around metal-on-metal arthroplasty: an RNA-Seq-based study
A Pemmari (Speaker), T Leppänen (Speaker), T Moilanen (Speaker) & E Moilanen (Speaker)
25 Jan 2018Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by next generation sequencing -based genome wide expression analysis
Antti Pemmari (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
3 Nov 2017Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by RNA-Seq-based genome wide expression analysis
Antti Pemmari (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Katriina Vuolteenaho (Contributor)
26 Oct 2017Activity: Talk or presentation › Conference presentation
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MKP-1 as a protective factor and novel drug target in scleroderma: MKP-1 deficient mice develop more severe dermal fibrosis in a widely used experimental model of scleroderma
Morena Scotece (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
26 Oct 2017Activity: Talk or presentation › Conference presentation
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CAMP enhancing drugs salbutamol and rolipram augment the alternative activation of murine macrophages through MKP-1
Tiina Leppänen (Speaker), Mari Hämäläinen (Speaker) & Eeva Moilanen (Speaker)
11 Jul 2017Activity: Talk or presentation › Conference presentation
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MKP-1 as a protective factor and novel drug target in scleroderma: MKP-1 deficient mice develop more severe dermal fibrosis in a widely used experimental model of scleroderma
Morena Scotece (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
14 Jun 2017Activity: Talk or presentation › Conference presentation
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MKP-1 as a protective factor and novel drug target in scleroderma: MKP-1 deficient mice develop more severe dermal fibrosis in a widely used experimental model of scleroderma
Morena Scotece (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
22 Mar 2017Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by NGS-based genome wide expression analysis
Antti Pemmari (Contributor), Mari Hämäläinen (Contributor), Tiina Leppänen (Contributor) & Eeva Moilanen (Contributor)
22 Mar 2017Activity: Talk or presentation › Conference presentation
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Widespread regulation of gene expression by glucocorticoids in chondrocytes from OA patients as determined by NGS-based genome wide expression analysis
Antti Pemmari (Speaker), Mari Hämäläinen (Speaker), Tiina Leppänen (Speaker) & Eeva Moilanen (Speaker)
27 Jan 2017Activity: Talk or presentation › Conference presentation
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Enhanced severity of experimentally-induced dermal scleroderma in mitogen-activated protein kinase phosphatase-1 (MKP-1) deficient mice
Morena Scotece (Speaker), M Hämäläinen (Speaker), T Leppänen (Speaker) & E Moilanen (Speaker)
27 Jan 2017Activity: Talk or presentation › Conference presentation
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Synthesis of psoralen derivatives and their anti-inflammatory properties. Emerging tarhets and molecules in middle space
J Timonen (Contributor), K Vuolteenaho (Contributor), T Leppänen (Contributor), R Nieminen (Contributor), P Aulaskari (Contributor), J Jänis (Contributor), P Vainiotalo (Contributor) & E Moilanen (Contributor)
24 Aug 2015Activity: Talk or presentation › Conference presentation
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YKL-40, a NOVEL marker of inflammation, is elevated after coronary artery bypass grafting surgery and correlates with troponin T release
Antti Laurikka (Contributor), Mari Hämäläinen (Contributor), Jari Laurikka (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor), Matti Tarkka (Contributor) & Katriina Vuolteenaho (Contributor)
19 Mar 2014Activity: Talk or presentation › Conference presentation
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PI3K/Akt Pahtway as an anti-inflammatory drug target
Heikki Eräsalo (Contributor), Mari Hämäläinen (Contributor), Mirka Laavola (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Riina Nieminen (Contributor)
19 Mar 2014Activity: Talk or presentation › Conference presentation
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PI3K/Akt pathway as an anti-inflammatory drug target
Heikki Eräsalo (Contributor), Mari Hämäläinen (Contributor), Mirka Laavola (Contributor), Tiina Leppänen (Contributor), Eeva Moilanen (Contributor) & Riina Nieminen (Contributor)
13 Feb 2014Activity: Talk or presentation › Conference presentation