Centre of Excellence in Body-On-Chip Research

CoEBoC bases on strong collaboration between the participating research groups. CoE combines knowhow in biological and engineering sciences and aims to develop a new “body-on-chip” platform. The platform will consist of several cultured tissue blocks connected with cultured vasculature and nervous systems. By posing hypoxic conditions to different parts of the system, we can study hypoxia-related diseases, such as cardiac ischemia. To achieve this ambitious goal, we will combine multi-disciplinary expertise on human stem cells, biomaterials, sensors, microfluidics, biomodeling and bioimaging. CoEBoC will produce new comprehensive knowledge for example on understanding tissue interactions, constructing complex in vitro tissue co-cultures and controlling their functionalities. The resulting expertise and technologies will improve for example development of new personalized treatments and drug development.