A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine

V. Le Joncour; A. Martins; M. Puhka; J. Isola; M. Salmikangas; P. Laakkonen; H. Joensuu; M. Barok

doi:10.1158/1535-7163.MCT-19-0207

A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine

V. Le Joncour, A. Martins, M. Puhka, J. Isola, M. Salmikangas, P. Laakkonen, H. Joensuu, M. Barok

Research output: Contribution to journal › Article › Scientific › peer-review

73 Citations (Scopus)

Original language	English
Pages (from-to)	1721-1730
Journal	Molecular cancer therapeutics
Volume	18
Issue number	10
DOIs	https://doi.org/10.1158/1535-7163.MCT-19-0207
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

Keywords

HER2
T-DM1
XMT-1522
antibody-drug conjugate
breast cancer
gastric cancer

Publication forum classification

Publication forum level 1

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1158/1535-7163.MCT-19-0207

http://urn.fi/URN:NBN:fi:tuni-201910223991

Cite this

@article{5cbc44b8a64242a2be0efa67be6aeaa4,

title = "A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine",

keywords = "HER2, T-DM1, XMT-1522, antibody-drug conjugate, breast cancer, gastric cancer, HER2, T-DM1, XMT-1522, antibody-drug conjugate, breast cancer, gastric cancer",

author = "{Le Joncour}, V. and A. Martins and M. Puhka and J. Isola and M. Salmikangas and P. Laakkonen and H. Joensuu and M. Barok",

year = "2019",

doi = "10.1158/1535-7163.MCT-19-0207",

language = "English",

volume = "18",

pages = "1721--1730",

number = "10",

}

TY - JOUR

T1 - A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine

AU - Le Joncour, V.

AU - Martins, A.

AU - Puhka, M.

AU - Isola, J.

AU - Salmikangas, M.

AU - Laakkonen, P.

AU - Joensuu, H.

AU - Barok, M.

PY - 2019

Y1 - 2019

KW - HER2

KW - T-DM1

KW - XMT-1522

KW - antibody-drug conjugate

KW - breast cancer

KW - gastric cancer

KW - HER2

KW - T-DM1

KW - XMT-1522

KW - antibody-drug conjugate

KW - breast cancer

KW - gastric cancer

U2 - 10.1158/1535-7163.MCT-19-0207

DO - 10.1158/1535-7163.MCT-19-0207

M3 - Article

SN - 1538-8514

VL - 18

SP - 1721

EP - 1730

JO - Molecular cancer therapeutics

JF - Molecular cancer therapeutics

IS - 10

ER -