Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma

KEYNOTE-564 Investigators; T. K. Choueiri; P. Tomczak; S. H. Park; B. Venugopal; T. Ferguson; Y. H. Chang; J. Hajek; S. N. Symeonides; J. L. Lee; N. Sarwar; A. Thiery-Vuillemin; M. Gross-Goupil; M. Mahave; N. B. Haas; P. Sawrycki; H. Gurney; C. Chevreau; B. Melichar; E. Kopyltsov; A. Alva; J. M. Burke; G. Doshi; D. Topart; S. Oudard; H. Hammers; H. Kitamura; J. Bedke; R. F. Perini; P. Zhang; K. Imai; J. Willemann-Rogerio; D. I. Quinn; T. Powles; Pirkko-Liisa Kellokumpu-Lehtinen

doi:10.1056/nejmoa2106391

Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma

KEYNOTE-564 Investigators
, T. K. Choueiri^*
, P. Tomczak
, S. H. Park
, B. Venugopal
, T. Ferguson
, Y. H. Chang
, J. Hajek
, S. N. Symeonides
, J. L. Lee
, N. Sarwar
, A. Thiery-Vuillemin
, M. Gross-Goupil
, M. Mahave
, N. B. Haas
, P. Sawrycki
, H. Gurney
, C. Chevreau
, B. Melichar
, E. Kopyltsov

A. Alva, J. M. Burke, G. Doshi, D. Topart, S. Oudard, H. Hammers, H. Kitamura, J. Bedke, R. F. Perini, P. Zhang, K. Imai, J. Willemann-Rogerio, D. I. Quinn, T. Powles, Pirkko-Liisa Kellokumpu-Lehtinen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

706 Citations (Scopus)

Abstract

Original language	English
Pages (from-to)	683-694
Number of pages	12
Journal	New England Journal of Medicine
Volume	385
Issue number	8
DOIs	https://doi.org/10.1056/nejmoa2106391
Publication status	Published - 2021
Externally published	Yes
Publication type	A1 Journal article-refereed

Funding

Supported by Merck Sharp and Dohme, a subsidiary of Merck. Dr. Choueiri is supported in part by the Dana–Farber/Harvard Cancer Center Kidney Specialized Program of Research Excellence (2P50CA101942-16), by a grant (5P30CA006516-56) from the National Cancer Institute, and by the Kohlberg Chair at Harvard Medical School, the Trust Family, Michael Brigham, and Loker Pinard Funds for Kidney Cancer Research at Dana–Farber Cancer Institute.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Publication forum classification

Publication forum level 3

ASJC Scopus subject areas

General Medicine

Access to Document

10.1056/nejmoa2106391

Cite this

KEYNOTE-564 Investigators, Choueiri, T. K., Tomczak, P., Park, S. H., Venugopal, B., Ferguson, T., Chang, Y. H., Hajek, J., Symeonides, S. N., Lee, J. L., Sarwar, N., Thiery-Vuillemin, A., Gross-Goupil, M., Mahave, M., Haas, N. B., Sawrycki, P., Gurney, H., Chevreau, C., Melichar, B., ... Kellokumpu-Lehtinen, P.-L. (2021). Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma. New England Journal of Medicine, 385(8), 683-694. https://doi.org/10.1056/nejmoa2106391

@article{d8597acc83d048b794de3066fe6763e1,

title = "Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma",

author = "\{KEYNOTE-564 Investigators\} and Choueiri, \{T. K.\} and P. Tomczak and Park, \{S. H.\} and B. Venugopal and T. Ferguson and Chang, \{Y. H.\} and J. Hajek and Symeonides, \{S. N.\} and Lee, \{J. L.\} and N. Sarwar and A. Thiery-Vuillemin and M. Gross-Goupil and M. Mahave and Haas, \{N. B.\} and P. Sawrycki and H. Gurney and C. Chevreau and B. Melichar and E. Kopyltsov and A. Alva and Burke, \{J. M.\} and G. Doshi and D. Topart and S. Oudard and H. Hammers and H. Kitamura and J. Bedke and Perini, \{R. F.\} and P. Zhang and K. Imai and J. Willemann-Rogerio and Quinn, \{D. I.\} and T. Powles and Pirkko-Liisa Kellokumpu-Lehtinen",

year = "2021",

doi = "10.1056/nejmoa2106391",

language = "English",

volume = "385",

pages = "683--694",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

number = "8",

}

KEYNOTE-564 Investigators, Choueiri, TK, Tomczak, P, Park, SH, Venugopal, B, Ferguson, T, Chang, YH, Hajek, J, Symeonides, SN, Lee, JL, Sarwar, N, Thiery-Vuillemin, A, Gross-Goupil, M, Mahave, M, Haas, NB, Sawrycki, P, Gurney, H, Chevreau, C, Melichar, B, Kopyltsov, E, Alva, A, Burke, JM, Doshi, G, Topart, D, Oudard, S, Hammers, H, Kitamura, H, Bedke, J, Perini, RF, Zhang, P, Imai, K, Willemann-Rogerio, J, Quinn, DI, Powles, T & Kellokumpu-Lehtinen, P-L 2021, 'Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma', New England Journal of Medicine, vol. 385, no. 8, pp. 683-694. https://doi.org/10.1056/nejmoa2106391

TY - JOUR

T1 - Adjuvant pembrolizumab after nephrectomy in renal-cell carcinoma

AU - KEYNOTE-564 Investigators

AU - Choueiri, T. K.

AU - Tomczak, P.

AU - Park, S. H.

AU - Venugopal, B.

AU - Ferguson, T.

AU - Chang, Y. H.

AU - Hajek, J.

AU - Symeonides, S. N.

AU - Lee, J. L.

AU - Sarwar, N.

AU - Thiery-Vuillemin, A.

AU - Gross-Goupil, M.

AU - Mahave, M.

AU - Haas, N. B.

AU - Sawrycki, P.

AU - Gurney, H.

AU - Chevreau, C.

AU - Melichar, B.

AU - Kopyltsov, E.

AU - Alva, A.

AU - Burke, J. M.

AU - Doshi, G.

AU - Topart, D.

AU - Oudard, S.

AU - Hammers, H.

AU - Kitamura, H.

AU - Bedke, J.

AU - Perini, R. F.

AU - Zhang, P.

AU - Imai, K.

AU - Willemann-Rogerio, J.

AU - Quinn, D. I.

AU - Powles, T.

AU - Kellokumpu-Lehtinen, Pirkko-Liisa

PY - 2021

Y1 - 2021

U2 - 10.1056/nejmoa2106391

DO - 10.1056/nejmoa2106391

M3 - Article

C2 - 34407342

AN - SCOPUS:85113283089

SN - 0028-4793

VL - 385

SP - 683

EP - 694

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 8

ER -