ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

K Kaipio; S Potdar; J Hynninen; A Auranen; S Grénman; K Wennerberg; S Hautaniemi; O Carpén; P Chen; P Roering; K Huhtinen; P Mikkonen; P Östling; L Lehtinen; N Mansuri; T Korpela

doi:10.1002/path.5356

ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

K Kaipio
, S Potdar
, J Hynninen
, A Auranen
, S Grénman
, K Wennerberg
, S Hautaniemi
, O Carpén
, P Chen
, P Roering
, K Huhtinen
, P Mikkonen
, P Östling
, L Lehtinen
, N Mansuri
, T Korpela

Research output: Contribution to journal › Article › Scientific › peer-review

46 Citations (Scopus)

Original language	English
Pages (from-to)	159-169
Journal	Journal of Pathology
Volume	250
Issue number	2
DOIs	https://doi.org/10.1002/path.5356
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

drug sensitivity
ovarian cancer
patient-derived cell line
stem-like cell
survival

Publication forum classification

Publication forum level 2

Access to Document

10.1002/path.5356

https://pubmed.ncbi.nlm.nih.gov/31595974

Cite this

Kaipio, K., Potdar, S., Hynninen, J., Auranen, A., Grénman, S., Wennerberg, K., Hautaniemi, S., Carpén, O., Chen, P., Roering, P., Huhtinen, K., Mikkonen, P., Östling, P., Lehtinen, L., Mansuri, N., & Korpela, T. (2019). ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors. Journal of Pathology, 250(2), 159-169. https://doi.org/10.1002/path.5356

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title = "ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors",

keywords = "drug sensitivity, ovarian cancer, patient-derived cell line, stem-like cell, survival, drug sensitivity, ovarian cancer, patient-derived cell line, stem-like cell, survival",

author = "K Kaipio and S Potdar and J Hynninen and A Auranen and S Gr{\'e}nman and K Wennerberg and S Hautaniemi and O Carp{\'e}n and P Chen and P Roering and K Huhtinen and P Mikkonen and P {\"O}stling and L Lehtinen and N Mansuri and T Korpela",

year = "2019",

doi = "10.1002/path.5356",

language = "English",

volume = "250",

pages = "159--169",

journal = "Journal of Pathology",

issn = "0022-3417",

publisher = "John Wiley \& Sons",

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}

Kaipio, K, Potdar, S, Hynninen, J, Auranen, A, Grénman, S, Wennerberg, K, Hautaniemi, S, Carpén, O, Chen, P, Roering, P, Huhtinen, K, Mikkonen, P, Östling, P, Lehtinen, L, Mansuri, N & Korpela, T 2019, 'ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors', Journal of Pathology, vol. 250, no. 2, pp. 159-169. https://doi.org/10.1002/path.5356

TY - JOUR

T1 - ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

AU - Kaipio, K

AU - Potdar, S

AU - Hynninen, J

AU - Auranen, A

AU - Grénman, S

AU - Wennerberg, K

AU - Hautaniemi, S

AU - Carpén, O

AU - Chen, P

AU - Roering, P

AU - Huhtinen, K

AU - Mikkonen, P

AU - Östling, P

AU - Lehtinen, L

AU - Mansuri, N

AU - Korpela, T

PY - 2019

Y1 - 2019

KW - drug sensitivity

KW - ovarian cancer

KW - patient-derived cell line

KW - stem-like cell

KW - survival

KW - drug sensitivity

KW - ovarian cancer

KW - patient-derived cell line

KW - stem-like cell

KW - survival

U2 - 10.1002/path.5356

DO - 10.1002/path.5356

M3 - Article

SN - 0022-3417

VL - 250

SP - 159

EP - 169

JO - Journal of Pathology

JF - Journal of Pathology

IS - 2

ER -