An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels

Sumanta Samanta, Vignesh K. Rangasami, N. Arul Murugan, Vijay Singh Parihar, Oommen P. Varghese, Oommen P. Oommen

Research output: Contribution to journalArticleScientificpeer-review

Abstract

We present here a new insight into the chemical reactivity and bioactivity of dopamine (DA) and gallic acid (GA) and their hyaluronic acid (HA) conjugates. Our data suggest that HA-GA scaffolds are superior to HA-DA, with higher oxidation kinetics, improved tissue adhesive properties, and radical scavenging ability with a lower pro-inflammatory response. This journal is

Original languageEnglish
Pages (from-to)2987-2991
Number of pages5
JournalPolymer Chemistry
Volume12
Issue number20
DOIs
Publication statusPublished - 2021
Publication typeA1 Journal article-refereed

Publication forum classification

  • Publication forum level 2

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Organic Chemistry
  • Polymers and Plastics

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