Abstract
<p>OBJECTIVE: In this study, we propose a method for finding
: atherosclerotic changes based on the ratios of areas under peripheral arterial pulse
: wave (PW) contours and analyze its performance.</p><p>APPROACH: The PW signals
: were recorded with force sensors and photoplethysmographic sensors from ankle,
: wrist, cubital fossa, index finger and second toe from 30 atherosclerotic patients
: and 52 control subjects. In addition, day-to-day repeatability of the method
: was studied with 10 test subjects examined on 3 different days. The ratios of
: areas under the PWs were computed and the results were evaluated by means
: of receiver operating characteristic (ROC) analysis, intra-class correlation (ICC)
: coefficient and multiple linear regression analysis.</p><p>MAIN RESULTS: Areas under
: ROC curves of 0.802-0.906 were found for different area ratios having statistically
: significant differences between the atheroslerotic group and control groups. ICCs
: over 0.80 were found widely for the beat-by-beat analyzed data and over 0.95 for
: the data based on the averages over different numbers of PWs. Multiple linear
: regression analysis showed linear dependence between the area ratios and age
: and the diagnosis of atherosclerosis.</p><p>SIGNIFICANCE: Our findings may facilitate
: development of novel diagnostic approaches and preventive strategies against
: cardiovascular disorders. However, further studies are needed to confirm the
: results. The presented study demonstrates the potential of arterial PW analysis
: in finding vascular abnormalities.
.</p>
| Original language | English |
|---|---|
| Journal | Physiological Measurement |
| Volume | 39 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2018 |
| Publication type | A1 Journal article-refereed |
Keywords
- Journal Article
- atherosclerosis
- electromechanical sensors
- photoplethysmography
- pulse wave measurement
Publication forum classification
- Publication forum level 1