Association between admission criteria and body composition among young children with moderate acute malnutrition, a cross-sectional study from Burkina Faso

Christian Fabiansen, Bernardette Cichon, Charles W. Yaméogo, Ann-Sophie Iuel-Brockdorf, Kevin P. Q. Phelan, Jonathan C. Wells, Christian Ritz, Suzanne Filteau, André Briend, Vibeke B. Christensen, Per Ashorn, Kim F. Michaelsen, Susan Shepherd, Henrik Friis

    Research output: Contribution to journalArticleScientificpeer-review

    3 Citations (Scopus)

    Abstract

    Children with moderate acute malnutrition (MAM) are treated based on low weight‑for‑length z‑score (WLZ), low mid‑upper arm circumference (MUAc) or both. this study aimed to assess associations of admission criteria and body composition (Bc), to improve treatment of MAM. We undertook a cross-sectional study among 6–23 months old Burkinabe children with MAM. Fat-free (FFM) and fat mass (fM) were determined by deuterium dilution and expressed as ffM (ffMi) and fM index (fMi). Of 1,489 children, 439 (29.5%) were recruited by low MUAC only (MUAC-O), 734 (49.3%) by low WLZ and low MUAC (WLZ-MUAC) and 316 (21.2%) by low WLZ only (WLZ-O). Thus, 1,173 (78.8%) were recruited by low MUAC, with or without low WLZ (ALL-MUAC). After adjustments, WLZ-O had 89 g
    (95% confidence interval (CI) 5; 172) lower FFM compared to MUAC-O. Similarly, WLZ-O had 0.89 kg/m2 (95% CI 0.77; 1.01) lower FFMI compared to MUAC-O, whereas there was no difference for FMI. However, boys included by WLZ-O compared to MUAC-O had 0.21 kg/m2 (95% CI 0.05; 0.38) higher
    FMI. In contrast, girls included by WLZ-O had 0.17 (95% CI 0.01; 0.33) kg/m2 lower fMi compared to MUAC-O (interaction, p = 0.002). We found that different criteria for admission into MAM treatment programmes select children with differences in BC, especially FFMI.
    Trial registration: ISRCTN42569496.
    Original languageEnglish
    Article number13266
    Pages (from-to)13266
    JournalScientific Reports
    Volume6;10
    Issue number1
    DOIs
    Publication statusPublished - 2020
    Publication typeA1 Journal article-refereed

    Keywords

    • Nutrition
    • Paediatric research

    Publication forum classification

    • Publication forum level 1

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