Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

J. Tynkkynen; V. Chouraki; S.J. van der Lee; J. Hernesniemi; Q. Yang; S. Li; A. Beiser; M.G. Larson; K. Sääksjärvi; M.J. Shipley; A. Singh-Manoux; R.E. Gerszten; T.J. Wang; A.S. Havulinna; P. Würtz; K. Fischer; A. Demirkan; M.A. Ikram; N. Amin; T. Lehtimäki; M. Kähönen; M. Perola; A. Metspalu; A.J. Kangas; P. Soininen; M. Ala-Korpela; R.S. Vasan; M. Kivimäki; C.M. van Duijn; S. Seshadri; V. Salomaa

doi:10.1016/j.jalz.2018.01.003

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

J. Tynkkynen
, V. Chouraki
, S.J. van der Lee
, J. Hernesniemi
, Q. Yang
, S. Li
, A. Beiser
, M.G. Larson
, K. Sääksjärvi
, M.J. Shipley
, A. Singh-Manoux
, R.E. Gerszten
, T.J. Wang
, A.S. Havulinna
, P. Würtz
, K. Fischer
, A. Demirkan
, M.A. Ikram
, N. Amin
, T. Lehtimäki

M. Kähönen, M. Perola, A. Metspalu, A.J. Kangas, P. Soininen, M. Ala-Korpela, R.S. Vasan, M. Kivimäki, C.M. van Duijn, S. Seshadri, V. Salomaa

Research output: Contribution to journal › Article › Scientific › peer-review

209 Citations (Scopus)

Original language	English
Pages (from-to)	723-733
Journal	Alzheimer's and Dementia
Volume	14
Issue number	6
DOIs	https://doi.org/10.1016/j.jalz.2018.01.003
Publication status	Published - 2018
Publication type	A1 Journal article-refereed

Keywords

Alzheimer's disease
Amino acids
Biomarkers
Dementia
Metabolomics

Publication forum classification

Publication forum level 1

Access to Document

10.1016/j.jalz.2018.01.003

http://urn.fi/urn:nbn:fi:uta-201809132535

Cite this

Tynkkynen, J., Chouraki, V., van der Lee, S. J., Hernesniemi, J., Yang, Q., Li, S., Beiser, A., Larson, M. G., Sääksjärvi, K., Shipley, M. J., Singh-Manoux, A., Gerszten, R. E., Wang, T. J., Havulinna, A. S., Würtz, P., Fischer, K., Demirkan, A., Ikram, M. A., Amin, N., ... Salomaa, V. (2018). Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts. Alzheimer's and Dementia, 14(6), 723-733. https://doi.org/10.1016/j.jalz.2018.01.003

@article{36b6febcc77c4622b181ea406f471e7b,

title = "Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts",

keywords = "Alzheimer's disease, Amino acids, Biomarkers, Dementia, Metabolomics, Alzheimer's disease, Amino acids, Biomarkers, Dementia, Metabolomics",

author = "J. Tynkkynen and V. Chouraki and \{van der Lee\}, S.J. and J. Hernesniemi and Q. Yang and S. Li and A. Beiser and M.G. Larson and K. S{\"a}{\"a}ksj{\"a}rvi and M.J. Shipley and A. Singh-Manoux and R.E. Gerszten and T.J. Wang and A.S. Havulinna and P. W{\"u}rtz and K. Fischer and A. Demirkan and M.A. Ikram and N. Amin and T. Lehtim{\"a}ki and M. K{\"a}h{\"o}nen and M. Perola and A. Metspalu and A.J. Kangas and P. Soininen and M. Ala-Korpela and R.S. Vasan and M. Kivim{\"a}ki and \{van Duijn\}, C.M. and S. Seshadri and V. Salomaa",

year = "2018",

doi = "10.1016/j.jalz.2018.01.003",

language = "English",

volume = "14",

pages = "723--733",

number = "6",

}

Tynkkynen, J, Chouraki, V, van der Lee, SJ, Hernesniemi, J, Yang, Q, Li, S, Beiser, A, Larson, MG, Sääksjärvi, K, Shipley, MJ, Singh-Manoux, A, Gerszten, RE, Wang, TJ, Havulinna, AS, Würtz, P, Fischer, K, Demirkan, A, Ikram, MA, Amin, N, Lehtimäki, T , Kähönen, M, Perola, M, Metspalu, A, Kangas, AJ, Soininen, P, Ala-Korpela, M, Vasan, RS, Kivimäki, M, van Duijn, CM, Seshadri, S & Salomaa, V 2018, 'Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts', Alzheimer's and Dementia, vol. 14, no. 6, pp. 723-733. https://doi.org/10.1016/j.jalz.2018.01.003

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts. / Tynkkynen, J.; Chouraki, V.; van der Lee, S.J. et al.
In: Alzheimer's and Dementia, Vol. 14, No. 6, 2018, p. 723-733.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

AU - Tynkkynen, J.

AU - Chouraki, V.

AU - van der Lee, S.J.

AU - Hernesniemi, J.

AU - Yang, Q.

AU - Li, S.

AU - Beiser, A.

AU - Larson, M.G.

AU - Sääksjärvi, K.

AU - Shipley, M.J.

AU - Singh-Manoux, A.

AU - Gerszten, R.E.

AU - Wang, T.J.

AU - Havulinna, A.S.

AU - Würtz, P.

AU - Fischer, K.

AU - Demirkan, A.

AU - Ikram, M.A.

AU - Amin, N.

AU - Lehtimäki, T.

AU - Kähönen, M.

AU - Perola, M.

AU - Metspalu, A.

AU - Kangas, A.J.

AU - Soininen, P.

AU - Ala-Korpela, M.

AU - Vasan, R.S.

AU - Kivimäki, M.

AU - van Duijn, C.M.

AU - Seshadri, S.

AU - Salomaa, V.

PY - 2018

Y1 - 2018

KW - Alzheimer's disease

KW - Amino acids

KW - Biomarkers

KW - Dementia

KW - Metabolomics

KW - Alzheimer's disease

KW - Amino acids

KW - Biomarkers

KW - Dementia

KW - Metabolomics

U2 - 10.1016/j.jalz.2018.01.003

DO - 10.1016/j.jalz.2018.01.003

M3 - Article

SN - 1552-5260

VL - 14

SP - 723

EP - 733

JO - Alzheimer's and Dementia

JF - Alzheimer's and Dementia

IS - 6

ER -