TY - JOUR
T1 - Beyond HRD Status
T2 - Unraveling Genetic Variants Impacting PARP Inhibitor Sensitivity in Advanced Ovarian Cancer
AU - Kjeldsen, Maj K.
AU - Jørgensen, Morten
AU - Grønseth, Dina Sofie B.
AU - Schønemann-Lund, Martin
AU - Nyvang, Gitte Bettina
AU - Haslund, Charlotte Aaquist
AU - Knudsen, Anja Oer
AU - Motavaf, Anne Krejbjerg
AU - Malander, Susanne
AU - Anttila, Maarit
AU - Lindahl, Gabriel
AU - Mäenpää, Johanna
AU - Dimoula, Maria
AU - Werner, Theresa L.
AU - Iversen, Trine Zeeberg
AU - Hietanen, Sakari
AU - Fokdal, Lars
AU - Dahlstrand, Hanna
AU - Bjørge, Line
AU - Birrer, Michael J.
AU - Mirza, Mansoor R.
AU - Rossing, Maria
N1 - Publisher Copyright:
©2024 The Authors; Published by the American Association for Cancer Research.
PY - 2024/12
Y1 - 2024/12
N2 - SIGNIFICANCE: The irregular response to PARPi in HRD-positive and -negative tumors highlights the need for identifying additional biomarkers. This study explores the mutational landscape beyond HRD status in AOC, ultimately advancing precision oncology in future clinical practice.
AB - SIGNIFICANCE: The irregular response to PARPi in HRD-positive and -negative tumors highlights the need for identifying additional biomarkers. This study explores the mutational landscape beyond HRD status in AOC, ultimately advancing precision oncology in future clinical practice.
U2 - 10.1158/2767-9764.CRC-24-0294
DO - 10.1158/2767-9764.CRC-24-0294
M3 - Article
C2 - 39591206
AN - SCOPUS:85214054632
SN - 2767-9764
VL - 4
SP - 3190
EP - 3200
JO - Cancer research communications
JF - Cancer research communications
IS - 12
ER -