Abstract
This communication describes a carefully designed strategy which blends biogenic silver nanoparticles with PVA scaffolds to fabricate SNP@PVA electrospun scaffolds with admirable physico-chemical properties. The hybrid scaffold demonstrated cyto-compatibility and hemo-compatibility with no adverse effects on the surrounding cells, as demonstrated by multiple assays. The growth of cancer cells was greatly prevented by SNP@PVA scaffolds, while allowing growth of normal cells. The outstanding antimicrobial features of the scaffold can be attributed to the presence of silver na-noparticles and proves the use of SNP@PVA for bio-medical applications.
| Original language | English |
|---|---|
| Pages (from-to) | 1735-1741 |
| Number of pages | 7 |
| Journal | Current Science |
| Volume | 116 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - May 2019 |
| Externally published | Yes |
| Publication type | A1 Journal article-refereed |
Funding
We thank the Kerala State Council for Science, Technology and Environment (No. KSCSTE/5166/2017-SRSHS dated 11/09/2017), Government of Kerala for financial support and University Grants Commission, New Delhi for providing research fellowships to G.U.P., B.S.U. and R.S.
| Funders |
|---|
| University Grants Commission |
| Kerala State Council for Science, Technology and Environment |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer cells
- Electrospinning
- Nanofibrous scaffold
- Polyvinyl alcohol
- Silver nanoparticles
ASJC Scopus subject areas
- General
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