Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus

P. Gao; J.-H. Xia; C. Sipeky; X.-M. Dong; Q. Zhang; Y. Yang; P. Zhang; S.P. Cruz; Cruz SPereira; K. Zhang; J. Zhu; H.-M. Lee; S. Suleman; N. Giannareas; S. Liu; T.L.J. Tammela; A. Auvinen; X. Wang; Q. Huang; L. Wang; A. Manninen; M.H. Vaarala; J. Schleutker; G.-H. Wei

doi:10.1016/j.cell.2018.06.003

Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus

P. Gao, J.-H. Xia, C. Sipeky, X.-M. Dong, Q. Zhang, Y. Yang, P. Zhang, S.P. Cruz, Cruz SPereira, K. Zhang, J. Zhu, H.-M. Lee, S. Suleman, N. Giannareas, S. Liu, T.L.J. Tammela, A. Auvinen, X. Wang, Q. Huang, L. WangA. Manninen, M.H. Vaarala, J. Schleutker, G.-H. Wei

Research output: Contribution to journal › Article › Scientific › peer-review

113 Citations (Scopus)

Original language	English
Pages (from-to)	576-589.e18
Journal	Cell
Volume	174
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2018.06.003
Publication status	Published - 2018
Publication type	A1 Journal article-refereed

Keywords

CEACAM21
GWAS
HOXA2
PCAT19
aggressive prostate cancer
allele-specific DNA-binding of transcription factor
eQTL
risk stratification
rs11672691
single cell CRISPR/Cas9-mediated editing

Publication forum classification

Publication forum level 3

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.cell.2018.06.003

Cite this

Gao, P., Xia, J.-H., Sipeky, C., Dong, X.-M., Zhang, Q., Yang, Y., Zhang, P., Cruz, S. P., SPereira, C., Zhang, K., Zhu, J., Lee, H.-M., Suleman, S., Giannareas, N., Liu, S., Tammela, T. L. J., Auvinen, A., Wang, X., Huang, Q., ... Wei, G.-H. (2018). Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus. Cell, 174(3), 576-589.e18. https://doi.org/10.1016/j.cell.2018.06.003

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title = "Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus",

keywords = "CEACAM21, GWAS, HOXA2, PCAT19, aggressive prostate cancer, allele-specific DNA-binding of transcription factor, eQTL, risk stratification, rs11672691, single cell CRISPR/Cas9-mediated editing, CEACAM21, GWAS, HOXA2, PCAT19, aggressive prostate cancer, allele-specific DNA-binding of transcription factor, eQTL, risk stratification, rs11672691, single cell CRISPR/Cas9-mediated editing",

author = "P. Gao and J.-H. Xia and C. Sipeky and X.-M. Dong and Q. Zhang and Y. Yang and P. Zhang and S.P. Cruz and Cruz SPereira and K. Zhang and J. Zhu and H.-M. Lee and S. Suleman and N. Giannareas and S. Liu and T.L.J. Tammela and A. Auvinen and X. Wang and Q. Huang and L. Wang and A. Manninen and M.H. Vaarala and J. Schleutker and G.-H. Wei",

year = "2018",

doi = "10.1016/j.cell.2018.06.003",

language = "English",

volume = "174",

pages = "576--589.e18",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "3",

}

Gao, P, Xia, J-H, Sipeky, C, Dong, X-M, Zhang, Q, Yang, Y, Zhang, P, Cruz, SP, SPereira, C, Zhang, K, Zhu, J, Lee, H-M, Suleman, S, Giannareas, N, Liu, S, Tammela, TLJ , Auvinen, A, Wang, X, Huang, Q, Wang, L, Manninen, A, Vaarala, MH, Schleutker, J & Wei, G-H 2018, 'Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus', Cell, vol. 174, no. 3, pp. 576-589.e18. https://doi.org/10.1016/j.cell.2018.06.003

TY - JOUR

T1 - Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus

AU - Gao, P.

AU - Xia, J.-H.

AU - Sipeky, C.

AU - Dong, X.-M.

AU - Zhang, Q.

AU - Yang, Y.

AU - Zhang, P.

AU - Cruz, S.P.

AU - SPereira, Cruz

AU - Zhang, K.

AU - Zhu, J.

AU - Lee, H.-M.

AU - Suleman, S.

AU - Giannareas, N.

AU - Liu, S.

AU - Tammela, T.L.J.

AU - Auvinen, A.

AU - Wang, X.

AU - Huang, Q.

AU - Wang, L.

AU - Manninen, A.

AU - Vaarala, M.H.

AU - Schleutker, J.

AU - Wei, G.-H.

PY - 2018

Y1 - 2018

KW - CEACAM21

KW - GWAS

KW - HOXA2

KW - PCAT19

KW - aggressive prostate cancer

KW - allele-specific DNA-binding of transcription factor

KW - eQTL

KW - risk stratification

KW - rs11672691

KW - single cell CRISPR/Cas9-mediated editing

KW - CEACAM21

KW - GWAS

KW - HOXA2

KW - PCAT19

KW - aggressive prostate cancer

KW - allele-specific DNA-binding of transcription factor

KW - eQTL

KW - risk stratification

KW - rs11672691

KW - single cell CRISPR/Cas9-mediated editing

U2 - 10.1016/j.cell.2018.06.003

DO - 10.1016/j.cell.2018.06.003

M3 - Article

SN - 0092-8674

VL - 174

SP - 576-589.e18

JO - Cell

JF - Cell

IS - 3

ER -