Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Oommen P. Varghese, Jianping Liu, Karthi Sundaram, Jöns Hilborn, Oommen Podiyan Oommen

    Research output: Contribution to journalArticleScientificpeer-review

    20 Citations (Scopus)

    Abstract

    Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

    Original languageEnglish
    Pages (from-to)1310-1313
    Number of pages4
    JournalBiomaterials Science
    Volume4
    Issue number9
    DOIs
    Publication statusPublished - 1 Sep 2016
    Publication typeA1 Journal article-refereed

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Materials Science(all)
    • Biomedical Engineering

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