Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case

Kaisa I. Lehtomäki; Laura I. Lahtinen; Nina Rintanen; Teijo Kuopio; Ivana Kholová; Rami Mäkelä; Juha K. Rantala; Pirkko-L.iisa Kellokumpu-Lehtinen; Pirkko-Liisa Kellokumpu-Lehtinen; Juha Kononen

doi:10.21873/anticanres.13791

Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case

Kaisa I. Lehtomäki
, Laura I. Lahtinen
, Nina Rintanen
, Teijo Kuopio
, Ivana Kholová
, Rami Mäkelä
, Juha K. Rantala
, Pirkko-L.iisa Kellokumpu-Lehtinen
, Pirkko-Liisa Kellokumpu-Lehtinen
, Juha Kononen

Research output: Contribution to journal › Article › Scientific › peer-review

9 Citations (Scopus)

Original language	English
Pages (from-to)	5867-5877
Journal	Anticancer Research
Volume	39
Issue number	11
DOIs	https://doi.org/10.21873/anticanres.13791
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

BRAFnonV600E mutations
Colorectal cancer
MEK/MAPK pathway
ctDNA
ex vivo drug screening
liquid biopsy

Publication forum classification

Publication forum level 1

Access to Document

10.21873/anticanres.13791

Cite this

@article{5c518ab63b3b47508a69f67ff224be8c,

title = "Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case",

keywords = "BRAFnonV600E mutations, Colorectal cancer, MEK/MAPK pathway, ctDNA, ex vivo drug screening, liquid biopsy, BRAFnonV600E mutations, Colorectal cancer, MEK/MAPK pathway, ctDNA, ex vivo drug screening, liquid biopsy",

author = "Lehtom{\"a}ki, \{Kaisa I.\} and Lahtinen, \{Laura I.\} and Nina Rintanen and Teijo Kuopio and Ivana Kholov{\'a} and Rami M{\"a}kel{\"a} and Rantala, \{Juha K.\} and Pirkko-L.iisa Kellokumpu-Lehtinen and Pirkko-Liisa Kellokumpu-Lehtinen and Juha Kononen",

year = "2019",

doi = "10.21873/anticanres.13791",

language = "English",

volume = "39",

pages = "5867--5877",

journal = "Anticancer Research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "11",

}

TY - JOUR

T1 - Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case

AU - Lehtomäki, Kaisa I.

AU - Lahtinen, Laura I.

AU - Rintanen, Nina

AU - Kuopio, Teijo

AU - Kholová, Ivana

AU - Mäkelä, Rami

AU - Rantala, Juha K.

AU - Kellokumpu-Lehtinen, Pirkko-L.iisa

AU - Kellokumpu-Lehtinen, Pirkko-Liisa

AU - Kononen, Juha

PY - 2019

Y1 - 2019

KW - BRAFnonV600E mutations

KW - Colorectal cancer

KW - MEK/MAPK pathway

KW - ctDNA

KW - ex vivo drug screening

KW - liquid biopsy

KW - BRAFnonV600E mutations

KW - Colorectal cancer

KW - MEK/MAPK pathway

KW - ctDNA

KW - ex vivo drug screening

KW - liquid biopsy

U2 - 10.21873/anticanres.13791

DO - 10.21873/anticanres.13791

M3 - Article

SN - 0250-7005

VL - 39

SP - 5867

EP - 5877

JO - Anticancer Research

JF - Anticancer Research

IS - 11

ER -