Cloning, characterization, and sulfonamide and thiol inhibition studies of an &#945;-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease

Peiwen Pan; Alane B Vermelho; Giseli Capaci Rodrigues; Andrea Scozzafava; Martti E Tolvanen; Seppo Parkkila; Clemente Capasso; Claudiu T Supuran

doi:10.1021/jm4000616

Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease

Peiwen Pan, Alane B Vermelho, Giseli Capaci Rodrigues, Andrea Scozzafava, Martti E Tolvanen, Seppo Parkkila, Clemente Capasso, Claudiu T Supuran

Department of Clinical Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

92 Citations (Scopus)

Original language	English
Pages (from-to)	1761-1771
Journal	Journal of Medicinal Chemistry
Volume	56
Issue number	4
DOIs	https://doi.org/10.1021/jm4000616
Publication status	Published - 2013
Publication type	A1 Journal article-refereed

Publication forum classification

Publication forum level 3

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/jm4000616

Cite this

Pan, P., Vermelho, A. B., Capaci Rodrigues, G., Scozzafava, A., Tolvanen, M. E., Parkkila, S., Capasso, C., & Supuran, C. T. (2013). Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. Journal of Medicinal Chemistry, 56(4), 1761-1771. https://doi.org/10.1021/jm4000616

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title = "Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease",

author = "Peiwen Pan and Vermelho, {Alane B} and {Capaci Rodrigues}, Giseli and Andrea Scozzafava and Tolvanen, {Martti E} and Seppo Parkkila and Clemente Capasso and Supuran, {Claudiu T}",

year = "2013",

doi = "10.1021/jm4000616",

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pages = "1761--1771",

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Pan, P, Vermelho, AB, Capaci Rodrigues, G, Scozzafava, A, Tolvanen, ME, Parkkila, S, Capasso, C & Supuran, CT 2013, 'Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease', Journal of Medicinal Chemistry, vol. 56, no. 4, pp. 1761-1771. https://doi.org/10.1021/jm4000616

Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. / Pan, Peiwen; Vermelho, Alane B; Capaci Rodrigues, Giseli et al.
In: Journal of Medicinal Chemistry, Vol. 56, No. 4, 2013, p. 1761-1771.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease

AU - Pan, Peiwen

AU - Vermelho, Alane B

AU - Capaci Rodrigues, Giseli

AU - Scozzafava, Andrea

AU - Tolvanen, Martti E

AU - Parkkila, Seppo

AU - Capasso, Clemente

AU - Supuran, Claudiu T

PY - 2013

Y1 - 2013

U2 - 10.1021/jm4000616

DO - 10.1021/jm4000616

M3 - Article

SN - 0022-2623

VL - 56

SP - 1761

EP - 1771

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry