Connectivity analysis of full montage EEG in traumatic brain injury patients in the ICU

T. Lipping, N. Erkintalo, M. Särkelä, R. S.K. Takala, A. Katila, J. Frantzén, J. P. Posti, M. Müller, O. Tenovuo

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

    2 Citations (Scopus)

    Abstract

    Long-term full montage (19 channels) electroencephalographic (EEG) recordings of 6 patients, treated in the Intensive Care Unit (ICU) for severe Traumatic Brain Injury (TBI), were analyzed using the methodology of connectivity analysis. Two connectivity measures, Coherence and Cross Frequency Coupling (CFC) were calculated for each pair of channels in two frequency bands, 8−13 Hz and 13−35 Hz. In the case of CFC, frequencies below 2 Hz were considered as the modulating rhythm. The ability of the measures to indicate the outcome of treatment was evaluated using the Mann-Whitney U-test. The results indicate that CFC values tend to be higher in good outcome patients for (modulating) frontal EEG channels. For the Coherence measure, U-statistic values close to 0.9 were obtained for some channel pairs, however, no clear pattern could be observed.

    Original languageEnglish
    Title of host publicationEMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017
    PublisherSpringer Verlag
    Pages97-100
    Number of pages4
    ISBN (Print)9789811051210
    DOIs
    Publication statusPublished - 2018
    Publication typeA4 Article in conference proceedings
    EventJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) -
    Duration: 1 Jan 1900 → …

    Publication series

    NameIFMBE Proceedings
    Volume65
    ISSN (Print)1680-0737

    Conference

    ConferenceJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC)
    Period1/01/00 → …

    Keywords

    • Connectivity analysis
    • Cross frequency coupling
    • Outcome prediction
    • Traumatic brain injury

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Biomedical Engineering
    • Bioengineering

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