Coronary artery disease diagnosis by means of heart rate variability analysis using respiratory information

D. Hernando, M. Kähönen, J. Lázaro, R. Lehtinen, T. Nieminen, K. Nikus, T. Lehtimäki, R. Bailón, J. Viik

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

    1 Citation (Scopus)

    Abstract

    Heart rate variability (HRV) analysis during exercise has been used to evaluate cardiovascular response to the stress of exercise, which may offer additional value than in rest condition. To properly analyze HRV during exercise, several challenges need to be addressed, such as including respiratory information and removing the dependance with the mean heart rate (HR) level. The objective of this work is to extract parameters from HRV analysis and respiratory information during exercise to evaluate their capability of diagnose coronary artery disease (CAD). Significant differences in mean HR were found due to medication effect in patients with CAD. By correcting the HRV parameters by mean HR, this effect is minimized. Power related to high frequency, when guided by respiration, results to have the best diagnosis capability (AUC > 0.7).

    Original languageEnglish
    Title of host publicationEMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017
    EditorsHannu Eskola
    PublisherSpringer Verlag
    Pages270-273
    Number of pages4
    ISBN (Print)978-981-10-5121-0
    DOIs
    Publication statusPublished - 2018
    Publication typeA4 Article in conference proceedings
    EventJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) -
    Duration: 1 Jan 2018 → …

    Publication series

    NameIFMBE Proceedings
    Volume65
    ISSN (Print)1680-0737

    Conference

    ConferenceJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC)
    Period1/01/18 → …

    Keywords

    • CAD diagnosis
    • Exercise test
    • Respiratory rate

    Publication forum classification

    • Publication forum level 1

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