DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase

Sanjay Kumar Bharti; Joshua A Sommers; Jun Zhou; Daniel L Kaplan; Johannes N Spelbrink; Jean-Louis Mergny; Robert M Brosh

doi:10.1074/jbc.m114.567073

DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase

Sanjay Kumar Bharti, Joshua A Sommers, Jun Zhou, Daniel L Kaplan, Johannes N Spelbrink, Jean-Louis Mergny, Robert M Brosh

Research output: Contribution to journal › Article › Scientific › peer-review

111 Citations (Scopus)

Original language	English
Pages (from-to)	29975-29993
Journal	Journal Of Biological Chemistry
Volume	289
Issue number	43
DOIs	https://doi.org/10.1074/jbc.m114.567073
Publication status	Published - 2014
Publication type	A1 Journal article-refereed

Publication forum classification

Publication forum level 2

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1074/jbc.m114.567073

Cite this

Bharti, S. K., Sommers, J. A., Zhou, J., Kaplan, D. L., Spelbrink, J. N., Mergny, J.-L., & Brosh, R. M. (2014). DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase. Journal Of Biological Chemistry, 289(43), 29975-29993. https://doi.org/10.1074/jbc.m114.567073

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title = "DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase",

author = "Bharti, {Sanjay Kumar} and Sommers, {Joshua A} and Jun Zhou and Kaplan, {Daniel L} and Spelbrink, {Johannes N} and Jean-Louis Mergny and Brosh, {Robert M}",

year = "2014",

doi = "10.1074/jbc.m114.567073",

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volume = "289",

pages = "29975--29993",

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Bharti, SK, Sommers, JA, Zhou, J, Kaplan, DL, Spelbrink, JN, Mergny, J-L & Brosh, RM 2014, 'DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase', Journal Of Biological Chemistry, vol. 289, no. 43, pp. 29975-29993. https://doi.org/10.1074/jbc.m114.567073

DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase. / Bharti, Sanjay Kumar; Sommers, Joshua A; Zhou, Jun et al.
In: Journal Of Biological Chemistry, Vol. 289, No. 43, 2014, p. 29975-29993.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase

AU - Bharti, Sanjay Kumar

AU - Sommers, Joshua A

AU - Zhou, Jun

AU - Kaplan, Daniel L

AU - Spelbrink, Johannes N

AU - Mergny, Jean-Louis

AU - Brosh, Robert M

PY - 2014

Y1 - 2014

U2 - 10.1074/jbc.m114.567073

DO - 10.1074/jbc.m114.567073

M3 - Article

SN - 0021-9258

VL - 289

SP - 29975

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JO - Journal Of Biological Chemistry

JF - Journal Of Biological Chemistry

IS - 43

ER -

Bharti SK, Sommers JA, Zhou J, Kaplan DL, Spelbrink JN, Mergny JL et al. DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase. Journal Of Biological Chemistry. 2014;289(43):29975-29993. doi: 10.1074/jbc.m114.567073