Dosimetric effect of rotational setup errors in volumetric modulated arc therapy and field-in-field treatment of left-sided breast cancer

Annele Heikkilä; Eeva Boman; Maija Rossi; Antti Vanhanen; Mikko Mankinen; Michiel Postema; Tuomas Koivumäki

doi:10.1016/j.ejmp.2023.103203

Dosimetric effect of rotational setup errors in volumetric modulated arc therapy and field-in-field treatment of left-sided breast cancer

Annele Heikkilä
, Eeva Boman
, Maija Rossi
, Antti Vanhanen
, Mikko Mankinen
, Michiel Postema
, Tuomas Koivumäki

Research output: Contribution to journal › Article › Scientific › peer-review

10 Citations (Scopus)

26 Downloads (Pure)

Abstract

Setup errors are an important factor in the dosimetric accuracy of radiotherapy delivery. In this study, we investigated how rotational setup errors influence the dose distribution in volumetric modulated arc therapy (VMAT) and tangential field-in-field (FiF) treatment of left-sided breast cancer with supraclavicular lymph node involvement in deep inspiration breath hold. Treatment planning computed tomography images and radiotherapy plans of 20 patients were collected retrospectively for the study. Rotational setup errors up to 3° were simulated by rotating the planning images, and the resulting dosimetric changes were calculated. With rotational setup errors up to 3°, the median decrease of V_95% to clinical target volume was less than 0.8 percentage point in both VMAT and FiF plans. The dose distribution of the heart and left anterior descending artery was more stable with respect to rotations in VMAT plans compared to FiF plans. Correction of 1° setup errors is recommended due to increased doses to the heart and left anterior descending artery after 1° setup errors.

Original language	English
Article number	103203
Number of pages	7
Journal	Physica Medica
Volume	117
DOIs	https://doi.org/10.1016/j.ejmp.2023.103203
Publication status	Published - 2024
Publication type	A1 Journal article-refereed

Funding

Support Foundation of Central Finland Central Hospital

Keywords

breast radiotherapy
robustness of VMAT
interfraction positioning errors
DICOM image rotation

Publication forum classification

Publication forum level 1

ASJC Scopus subject areas

Oncology
Radiation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ejmp.2023.103203Licence: CC BY

2024 Heikkilä EJMPFinal published version, 984 KBLicence: CC BY

https://urn.fi/URN:NBN:fi:tuni-202405145860Licence: CC BY

Cite this

@article{38b635090f9e44f0b6abc685beac1be8,

title = "Dosimetric effect of rotational setup errors in volumetric modulated arc therapy and field-in-field treatment of left-sided breast cancer",

abstract = "Setup errors are an important factor in the dosimetric accuracy of radiotherapy delivery. In this study, we investigated how rotational setup errors influence the dose distribution in volumetric modulated arc therapy (VMAT) and tangential field-in-field (FiF) treatment of left-sided breast cancer with supraclavicular lymph node involvement in deep inspiration breath hold. Treatment planning computed tomography images and radiotherapy plans of 20 patients were collected retrospectively for the study. Rotational setup errors up to 3° were simulated by rotating the planning images, and the resulting dosimetric changes were calculated. With rotational setup errors up to 3°, the median decrease of V95\% to clinical target volume was less than 0.8 percentage point in both VMAT and FiF plans. The dose distribution of the heart and left anterior descending artery was more stable with respect to rotations in VMAT plans compared to FiF plans. Correction of 1° setup errors is recommended due to increased doses to the heart and left anterior descending artery after 1° setup errors.",

keywords = "breast radiotherapy, robustness of VMAT, interfraction positioning errors, DICOM image rotation",

author = "Annele Heikkil{\"a} and Eeva Boman and Maija Rossi and Antti Vanhanen and Mikko Mankinen and Michiel Postema and Tuomas Koivum{\"a}ki",

year = "2024",

doi = "10.1016/j.ejmp.2023.103203",

language = "English",

volume = "117",

journal = "Physica Medica",

issn = "1120-1797",

publisher = "Associazione Italiana di Fisica Medica",

}

TY - JOUR

T1 - Dosimetric effect of rotational setup errors in volumetric modulated arc therapy and field-in-field treatment of left-sided breast cancer

AU - Heikkilä, Annele

AU - Boman, Eeva

AU - Rossi, Maija

AU - Vanhanen, Antti

AU - Mankinen, Mikko

AU - Postema, Michiel

AU - Koivumäki, Tuomas

PY - 2024

Y1 - 2024

N2 - Setup errors are an important factor in the dosimetric accuracy of radiotherapy delivery. In this study, we investigated how rotational setup errors influence the dose distribution in volumetric modulated arc therapy (VMAT) and tangential field-in-field (FiF) treatment of left-sided breast cancer with supraclavicular lymph node involvement in deep inspiration breath hold. Treatment planning computed tomography images and radiotherapy plans of 20 patients were collected retrospectively for the study. Rotational setup errors up to 3° were simulated by rotating the planning images, and the resulting dosimetric changes were calculated. With rotational setup errors up to 3°, the median decrease of V95% to clinical target volume was less than 0.8 percentage point in both VMAT and FiF plans. The dose distribution of the heart and left anterior descending artery was more stable with respect to rotations in VMAT plans compared to FiF plans. Correction of 1° setup errors is recommended due to increased doses to the heart and left anterior descending artery after 1° setup errors.

AB - Setup errors are an important factor in the dosimetric accuracy of radiotherapy delivery. In this study, we investigated how rotational setup errors influence the dose distribution in volumetric modulated arc therapy (VMAT) and tangential field-in-field (FiF) treatment of left-sided breast cancer with supraclavicular lymph node involvement in deep inspiration breath hold. Treatment planning computed tomography images and radiotherapy plans of 20 patients were collected retrospectively for the study. Rotational setup errors up to 3° were simulated by rotating the planning images, and the resulting dosimetric changes were calculated. With rotational setup errors up to 3°, the median decrease of V95% to clinical target volume was less than 0.8 percentage point in both VMAT and FiF plans. The dose distribution of the heart and left anterior descending artery was more stable with respect to rotations in VMAT plans compared to FiF plans. Correction of 1° setup errors is recommended due to increased doses to the heart and left anterior descending artery after 1° setup errors.

KW - breast radiotherapy

KW - robustness of VMAT

KW - interfraction positioning errors

KW - DICOM image rotation

U2 - 10.1016/j.ejmp.2023.103203

DO - 10.1016/j.ejmp.2023.103203

M3 - Article

SN - 1120-1797

VL - 117

JO - Physica Medica

JF - Physica Medica

M1 - 103203

ER -

Dosimetric effect of rotational setup errors in volumetric modulated arc therapy and field-in-field treatment of left-sided breast cancer

Abstract

Funding

Keywords

Publication forum classification

ASJC Scopus subject areas

UN SDGs

Access to Document

Fingerprint

Cite this