Early effects of adjuvant breast cancer radiotherapy on right ventricular systolic and diastolic function

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13 Citations (Scopus)

Abstract

Aim: Reduced right ventricular (RV) systolic function correlates with poor prognosis in several heart diseases. The aim of this prospective single-Center study was to investigate whether conformal three-dimensional (3D) breast cancer radiotherapy impairs RV function. Patients and Methods: Forty-nine patients with early-stage left-sided breast cancer underwent comprehensive two-dimensional (2D) echocardiography before and after radiotherapy. RV function was evaluated with tricuspid annular plane systolic excursion (TAPSE), pulsed tissue Doppler peak velocity at the lateral RV wall (S') and RV and venous flow analysis. Results: Radiotherapy reduced TAPSE from 24.5±4.0 mm to 22.4±3.9 mm (p

Original languageEnglish
Pages (from-to)2141-2147
Number of pages7
JournalAnticancer Research
Volume35
Issue number4
Publication statusPublished - 2015
Publication typeA1 Journal article-refereed

Keywords

  • Breast cancer
  • Radiotherapy
  • Right ventricle
  • TAPSE

Publication forum classification

  • Publication forum level 1

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