Abstract
Aim: Reduced right ventricular (RV) systolic function correlates with poor prognosis in several heart diseases. The aim of this prospective single-Center study was to investigate whether conformal three-dimensional (3D) breast cancer radiotherapy impairs RV function. Patients and Methods: Forty-nine patients with early-stage left-sided breast cancer underwent comprehensive two-dimensional (2D) echocardiography before and after radiotherapy. RV function was evaluated with tricuspid annular plane systolic excursion (TAPSE), pulsed tissue Doppler peak velocity at the lateral RV wall (S') and RV and venous flow analysis. Results: Radiotherapy reduced TAPSE from 24.5±4.0 mm to 22.4±3.9 mm (p
| Original language | English |
|---|---|
| Pages (from-to) | 2141-2147 |
| Number of pages | 7 |
| Journal | Anticancer Research |
| Volume | 35 |
| Issue number | 4 |
| Publication status | Published - 2015 |
| Publication type | A1 Journal article-refereed |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Breast cancer
- Radiotherapy
- Right ventricle
- TAPSE
Publication forum classification
- Publication forum level 1
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