TY - JOUR
T1 - Effects of reducing sedentary behavior on cardiorespiratory fitness in adults with metabolic syndrome
T2 - A 6-month RCT
AU - Norha, Jooa
AU - Sjöros, Tanja
AU - Garthwaite, Taru
AU - Laine, Saara
AU - Saarenhovi, Maria
AU - Kallio, Petri
AU - Laitinen, Kirsi
AU - Houttu, Noora
AU - Vähä-Ypyä, Henri
AU - Sievänen, Harri
AU - Löyttyniemi, Eliisa
AU - Vasankari, Tommi
AU - Knuuti, Juhani
AU - Kalliokoski, Kari K.
AU - Heinonen, Ilkka H.A.
N1 - Funding Information:
This study was conducted within the Centre of Excellence in Cardiovascular and Metabolic Research, supported by the Academy of Finland, University of Turku, Turku University Hospital, and Åbo Akademi University. We would like to thank the staff of the Department of Clinical Physiology and Nuclear Medicine at Turku University Hospital and Turku PET Centre for assistance in the data collection.
Funding Information:
This study was funded by the Academy of Finland, the Finnish Cultural Foundation, the Juho Vainio Foundation, the Hospital District of Southwest Finland, the Yrjö Jahnsson Foundation, the Turku University Foundation, the Finnish Diabetes Research Foundation, and the Päivikki and Sakari Sohlberg foundation. The funding bodies did not take part in designing the study, collecting, analyzing, or interpreting the data or preparing of the manuscript.
Publisher Copyright:
© 2023 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.
PY - 2023
Y1 - 2023
N2 - Introduction: Poor cardiorespiratory fitness (CRF) is associated with adverse health outcomes. Previous observational and cross-sectional studies have suggested that reducing sedentary behavior (SB) might improve CRF. Therefore, we investigated the effects of a 6-month intervention of reducing SB on CRF in 64 sedentary inactive adults with metabolic syndrome in a non-blind randomized controlled trial. Materials and Methods: In the intervention group (INT, n = 33), the aim was to reduce SB by 1 h/day for 6 months without increasing exercise training. Control group (CON, n = 31) was instructed to maintain their habitual SB and physical activity. Maximal oxygen uptake (VO2max) was measured by maximal graded bicycle ergometer test with respiratory gas measurements. Physical activity and SB were measured during the whole intervention using accelerometers. Results: Reduction in SB did not improve VO2max statistically significantly (group × time p > 0.05). Maximal absolute power output (Wmax) did not improve significantly but increased in INT compared to CON when scaled to fat free mass (FFM) (at 6 months INT 1.54 [95% CI: 1.41, 1.67] vs. CON 1.45 [1.32, 1.59] Wmax/kgFFM, p = 0.036). Finally, the changes in daily step count correlated positively with the changes in VO2max scaled to body mass and FFM (r = 0.31 and 0.30, respectively, p < 0.05). Discussion: Reducing SB without adding exercise training does not seem to improve VO2max in adults with metabolic syndrome. However, succeeding in increasing daily step count may increase VO2max.
AB - Introduction: Poor cardiorespiratory fitness (CRF) is associated with adverse health outcomes. Previous observational and cross-sectional studies have suggested that reducing sedentary behavior (SB) might improve CRF. Therefore, we investigated the effects of a 6-month intervention of reducing SB on CRF in 64 sedentary inactive adults with metabolic syndrome in a non-blind randomized controlled trial. Materials and Methods: In the intervention group (INT, n = 33), the aim was to reduce SB by 1 h/day for 6 months without increasing exercise training. Control group (CON, n = 31) was instructed to maintain their habitual SB and physical activity. Maximal oxygen uptake (VO2max) was measured by maximal graded bicycle ergometer test with respiratory gas measurements. Physical activity and SB were measured during the whole intervention using accelerometers. Results: Reduction in SB did not improve VO2max statistically significantly (group × time p > 0.05). Maximal absolute power output (Wmax) did not improve significantly but increased in INT compared to CON when scaled to fat free mass (FFM) (at 6 months INT 1.54 [95% CI: 1.41, 1.67] vs. CON 1.45 [1.32, 1.59] Wmax/kgFFM, p = 0.036). Finally, the changes in daily step count correlated positively with the changes in VO2max scaled to body mass and FFM (r = 0.31 and 0.30, respectively, p < 0.05). Discussion: Reducing SB without adding exercise training does not seem to improve VO2max in adults with metabolic syndrome. However, succeeding in increasing daily step count may increase VO2max.
KW - cardiorespiratory fitness
KW - cardiovascular disease
KW - obesity
KW - physical activity
KW - sedentary behavior
U2 - 10.1111/sms.14371
DO - 10.1111/sms.14371
M3 - Article
AN - SCOPUS:85153331259
SN - 0905-7188
VL - 33
SP - 1452
EP - 1461
JO - Scandinavian Journal of Medicine and Science in Sports
JF - Scandinavian Journal of Medicine and Science in Sports
IS - 8
ER -
