Abstract
There are no recent reports from the Nordic countries describing emergency department (ED) visits due to medication overdose. All patients visiting EDs of Tampere University Hospital, Finland, with ICD-10 codes T36–T50.9 during the year of 2021 were included in this study. A total of 803 ED visits by 631 individual patients were identified, comprising 0.7% of all ED visits in 2021. The intention of the overdose was self-harm in 70%, inebriation in 17% and other in 13% of the visits. The mean age of the patients was 35 (range 1–95) years, and 63% were female. In 52% of the visits, the patient had taken more than one medication. Benzodiazepines were involved in 40% of the visits, followed by antipsychotics (28%), antidepressants (19%), paracetamol (15%) and opiates (13%). Twenty-six percent of the patients were admitted to the intensive care or high-dependency care unit, but there were no overdose-related in-hospital deaths. The overall 1-year mortality rate after an overdose was 2.8%. The intention of a medication overdose was most often self-harm, followed by inebriation. Over half of the overdoses were multidrug overdoses, and psychoactive medications were predominantly used. There were no in-hospital deaths related to medication overdoses.
Original language | English |
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Article number | e70053 |
Number of pages | 8 |
Journal | Basic and Clinical Pharmacology and Toxicology |
Volume | 136 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2025 |
Publication type | A1 Journal article-refereed |
Keywords
- antidote
- inebriation
- mortality
- overdose
- self-harm
- suicide
- toxicology
Publication forum classification
- Publication forum level 2
ASJC Scopus subject areas
- Toxicology
- Pharmacology