Emergency Department Visits due to Medication Overdose in a Finnish University Hospital

Sami Mustajoki, Aleksi Reito, Kalle Peltonen

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Abstract

There are no recent reports from the Nordic countries describing emergency department (ED) visits due to medication overdose. All patients visiting EDs of Tampere University Hospital, Finland, with ICD-10 codes T36–T50.9 during the year of 2021 were included in this study. A total of 803 ED visits by 631 individual patients were identified, comprising 0.7% of all ED visits in 2021. The intention of the overdose was self-harm in 70%, inebriation in 17% and other in 13% of the visits. The mean age of the patients was 35 (range 1–95) years, and 63% were female. In 52% of the visits, the patient had taken more than one medication. Benzodiazepines were involved in 40% of the visits, followed by antipsychotics (28%), antidepressants (19%), paracetamol (15%) and opiates (13%). Twenty-six percent of the patients were admitted to the intensive care or high-dependency care unit, but there were no overdose-related in-hospital deaths. The overall 1-year mortality rate after an overdose was 2.8%. The intention of a medication overdose was most often self-harm, followed by inebriation. Over half of the overdoses were multidrug overdoses, and psychoactive medications were predominantly used. There were no in-hospital deaths related to medication overdoses.

Original languageEnglish
Article numbere70053
Number of pages8
JournalBasic and Clinical Pharmacology and Toxicology
Volume136
Issue number6
DOIs
Publication statusPublished - Jun 2025
Publication typeA1 Journal article-refereed

Keywords

  • antidote
  • inebriation
  • mortality
  • overdose
  • self-harm
  • suicide
  • toxicology

Publication forum classification

  • Publication forum level 2

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

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