Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms

Heini Flinck; Dominik Kerimov; Bruno Luukinen; Tapio Seiskari; Janne Aittoniemi

doi:10.1016/j.diagmicrobio.2021.115628

Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms

Heini Flinck, Dominik Kerimov, Bruno Luukinen, Tapio Seiskari, Janne Aittoniemi

Department of Clinical Microbiology

Research output: Contribution to journal › Article › Scientific › peer-review

6 Citations (Scopus)

Abstract

We evaluated a rapid antigen test against SARS-CoV-2 virus (Roche-SD Biosensor; RSDB-RAT) in children and adults with respiratory symptoms compared to those with nonrespiratory symptoms or asymptomatic. Also the performance of RSDB-RAT with respect to the duration of respiratory symptoms was assessed. A viral cross-reactivity panel was included. RSDB-RAT was reliable in detecting SARS-CoV-2 in children and adults if the respiratory symptoms had endured 1 to 7 days. If the respiratory symptoms had lasted less than 1 day, the sensitivity was significantly lower. No cross-reactivity with other respiratory viruses was observed.

Original language	English
Article number	115628
Journal	DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume	102
Issue number	4
Early online date	Dec 2021
DOIs	https://doi.org/10.1016/j.diagmicrobio.2021.115628
Publication status	Published - Apr 2022
Publication type	A1 Journal article-refereed

Funding

The study was supported by an institutional grant of Tampere Tuberculosis Foundation (Tampere, Finland). The funder had no role of study design, data collection and interpretation, or the decision to submit the work for publication.

Keywords

COVID-19
Rapid antigen test
SARS-CoV-2

Publication forum classification

Publication forum level 1

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diagmicrobio.2021.115628

Cite this

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title = "Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms",

abstract = "We evaluated a rapid antigen test against SARS-CoV-2 virus (Roche-SD Biosensor; RSDB-RAT) in children and adults with respiratory symptoms compared to those with nonrespiratory symptoms or asymptomatic. Also the performance of RSDB-RAT with respect to the duration of respiratory symptoms was assessed. A viral cross-reactivity panel was included. RSDB-RAT was reliable in detecting SARS-CoV-2 in children and adults if the respiratory symptoms had endured 1 to 7 days. If the respiratory symptoms had lasted less than 1 day, the sensitivity was significantly lower. No cross-reactivity with other respiratory viruses was observed.",

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Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms. / Flinck, Heini; Kerimov, Dominik ; Luukinen, Bruno et al.
In: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol. 102, No. 4, 115628, 04.2022.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Evaluation of the Roche-SD Biosensor rapid antigen test

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AU - Kerimov, Dominik

AU - Luukinen, Bruno

AU - Seiskari, Tapio

AU - Aittoniemi, Janne

PY - 2022/4

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Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms

Abstract

Funding

Keywords

Publication forum classification

ASJC Scopus subject areas

UN SDGs

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