Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal

Jarno M. A. Tanskanen; Annika Ahtiainen; Jari A. K. Hyttinen

doi:10.1109/ICECS46596.2019.8964854

Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal

Jarno M. A. Tanskanen, Annika Ahtiainen, Jari A. K. Hyttinen

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Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

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Abstract

Biological neuronal cells communicate using neurochemistry and electrical signals. Electrical stimulation (ES) is utilized to study neuronal cells and networks. Currently, ES is applied and responses observed in an open-loop fashion, which does not resemble natural network I/O. We hypothesize that real-time closed-loop full-duplex (simultaneous two-way) paradigms could provide deeper insight in natural neuronal networks, helping to understand our brains and to control neuronal network states to cure diseases. We present a minireview of ES-based extracellular in vitro neuroscience, our first long-term closed-loop ES experiment results as the proof-of-feasibility of the method, and our paradigm-shifting proposal of dialogical bio-ICT paradigms.

Original language	English
Title of host publication	2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS)
Publisher	IEEE
Pages	883-886
Number of pages	4
ISBN (Electronic)	978-1-7281-0996-1
ISBN (Print)	978-1-7281-0997-8
DOIs	https://doi.org/10.1109/ICECS46596.2019.8964854
Publication status	Published - Nov 2019
Publication type	A4 Article in conference proceedings
Event	IEEE International Conference on Electronics, Circuits and Systems - Duration: 31 Dec 1899 → …

Conference

Conference	IEEE International Conference on Electronics, Circuits and Systems
Period	31/12/99 → …

Keywords

bio-ICT interaction
biological neuronal networks
closed-loop control
DSP
electrical stimulation
open-loop control
real-time

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10.1109/ICECS46596.2019.8964854

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http://urn.fi/URN:NBN:fi:tuni-202102021858

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title = "Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal",

abstract = "Biological neuronal cells communicate using neurochemistry and electrical signals. Electrical stimulation (ES) is utilized to study neuronal cells and networks. Currently, ES is applied and responses observed in an open-loop fashion, which does not resemble natural network I/O. We hypothesize that real-time closed-loop full-duplex (simultaneous two-way) paradigms could provide deeper insight in natural neuronal networks, helping to understand our brains and to control neuronal network states to cure diseases. We present a minireview of ES-based extracellular in vitro neuroscience, our first long-term closed-loop ES experiment results as the proof-of-feasibility of the method, and our paradigm-shifting proposal of dialogical bio-ICT paradigms.",

keywords = "bio-ICT interaction, biological neuronal networks, closed-loop control, DSP, electrical stimulation, open-loop control, real-time",

author = "Tanskanen, {Jarno M. A.} and Annika Ahtiainen and Hyttinen, {Jari A. K.}",

year = "2019",

month = nov,

doi = "10.1109/ICECS46596.2019.8964854",

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note = "IEEE International Conference on Electronics, Circuits and Systems ; Conference date: 31-12-1899",

}

Tanskanen, JMA , Ahtiainen, A & Hyttinen, JAK 2019, Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal. in 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS). IEEE, pp. 883-886, IEEE International Conference on Electronics, Circuits and Systems, 31/12/99. https://doi.org/10.1109/ICECS46596.2019.8964854

Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal. / Tanskanen, Jarno M. A.; Ahtiainen, Annika ; Hyttinen, Jari A. K.
2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS). IEEE, 2019. p. 883-886.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

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Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal

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