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Factors Associated with Uptake of Routine Measles-Containing Vaccine Doses among Young Children, Oromia Regional State, Ethiopia, 2021

  • Abyot Bekele Woyessa*
  • , Monica P. Shah
  • , Binyam Moges Azmeraye
  • , Jeff Pan
  • , Leuel Lisanwork
  • , Getnet Yimer
  • , Shu Hua Wang
  • , J. Pekka Nuorti
  • , Miia Artama
  • , Almea M. Matanock
  • , Qian An
  • , Paulos Samuel
  • , Bekana Tolera
  • , Birhanu Kenate
  • , Abebe Bekele
  • , Tesfaye Deti
  • , Getachew Wako
  • , Amsalu Shiferaw
  • , Yohannes Lakew Tefera
  • , Melkamu Ayalew Kokebie
  • Tatek Bogale Anbessie, Habtamu Teklie Wubie, Aaron Wallace, Ciara E. Sugerman
*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)
41 Downloads (Pure)

Abstract

Recommended vaccination at nine months of age with the measles-containing vaccine (MCV1) has been part of Ethiopia’s routine immunization program since 1980. A second dose of MCV (MCV2) was introduced in 2019 for children 15 months of age. We examined MCV1 and MCV2 coverage and the factors associated with measles vaccination status. A cross-sectional household survey was conducted among caregivers of children aged 12–35 months in selected districts of Oromia Region. Measles vaccination status was determined using home-based records, when available, or caregivers’ recall. We analyzed the association between MCV1 and MCV2 vaccination status and household, caregiver, and child factors using logistic regression. The caregivers of 1172 children aged 12–35 months were interviewed and included in the analysis. MCV1 and MCV2 coverage was 71% and 48%, respectively. The dropout rate (DOR) from the first dose of Pentavalent vaccine to MCV1 was 22% and from MCV1 to MCV2 was 46%. Caregivers were more likely to vaccinate their children with MCV if they gave birth at a health facility, believe that their child had received all recommended vaccines, and know the required number of vaccination visits and doses. MCV2 coverage was low, with a high measles dropout rate (DOR). Caregivers with high awareness of MCV and its schedule were more likely to vaccinate their children. Intensified demand generation, defaulter tracking, and vaccine-stock management should be strengthened to improve MCV uptake.

Original languageEnglish
Article number762
Number of pages17
JournalVaccines
Volume12
Issue number7
DOIs
Publication statusPublished - Jul 2024
Publication typeA1 Journal article-refereed

Funding

Funding for this study was provided by Gavi, the Vaccine Alliance via the Ethiopia Targeted Country Assistance, Partner Engagement Framework, through the CDC-Foundation and from the US Centers for Disease Control and Prevention.

Funders
Vaccine Alliance
CDC Foundation
Centers for Disease Control and Prevention

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • barriers
    • dropout rate
    • Ethiopia
    • immunization coverage
    • MCV1
    • MCV2
    • measles
    • measles-containing vaccine
    • Oromia
    • second year of life

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Immunology
    • Pharmacology
    • Drug Discovery
    • Infectious Diseases
    • Pharmacology (medical)

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