Emerging wearable nano sensor networks enable a set of valuable applications in biomedical and environmental fields. At the same time, the current state of communication technologies significantly limits the processing capabilities of prospective nanomachines. Consequently, implying that all the analysis of collected data needs to be performed on a macro device. Therefore, to effectively enable long-awaited applications of nanonetworks their seamless integration into existing networking infrastructure is required, leading to the concept of Internet of Nano Things. In this paper, the interoperability between already deployed macro networks and emerging nano networks is preliminary investigated. The solution for this problem is nontrivial, as the existing macro wireless networks use primarily the carrier-based electromagnetic communications, while nanomachines must rely on ultra-low-power pulse-based EM radiation or inherently mobile objects as information carriers. Thus, the direct interaction between macro and nano networks is currently not feasible, forcing using special gateway nodes. Moreover, the modern solutions for nano communications have to be rapidly improved to enable construction of large-scale networks on top of existing link level techniques. Numerous theoretical questions are to be addressed to achieve this goal, ranging from the design of a proper modulation and coding technique to mitigation of noise and interference effects.