Abstract
The dative N-B bond was used to simply assemble heterocycles with a skeleton akin to the 5-oxofuro[2,3-b]furan motif. Twenty-five new N-B heterocycles were prepared via a highly efficient one-pot four-component reaction in yields and diastereoselectivities up to 95% and >97%, respectively. Several reaction intermediates were discovered using electrospray ionization mass spectroscopy which set the basis for the mechanism elucidation using DFT calculations.
Original language | English |
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Pages (from-to) | 988-991 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 14 |
Issue number | 4 |
DOIs | |
Publication status | Published - 17 Feb 2012 |
Publication type | A1 Journal article-refereed |
Funding
Fundacao para a Ciencia e Tecnologia (PTDC/QUI-QUI/118315/2010; PTDC/QUI-QUI/099389/2008; FRH/BPD/46589/2008;/48219/2008; Pest-OE/SAU/UI4013/2011; PEst-OE/QUI/UI0100/2011) are acknowledged for financial support.
Keywords
- BORON
- COMPLEXES
- NITROGEN