Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

P. Sakornsakolpat; D. Prokopenko; M. Lamontagne; N.F. Reeve; A.L. Guyatt; V.E. Jackson; N. Shrine; D. Qiao; T.M. Bartz; D.K. Kim; M.K. Lee; J.C. Latourelle; X. Li; J.D. Morrow; M. Obeidat; A.B. Wyss; P. Bakke; R.G. Barr; T.H. Beaty; S.A. Belinsky; G.G. Brusselle; J.D. Crapo; K. de Jong; D.L. DeMeo; T.E. Fingerlin; S.A. Gharib; A. Gulsvik; I.P. Hall; J.E. Hokanson; W.J. Kim; D.A. Lomas; S.J. London; D.A. Meyers; G.T. O'Connor; S.I. Rennard; D.A. Schwartz; P. Sliwinski; D. Sparrow; D.P. Strachan; R. Tal-Singer; Y. Tesfaigzi; J. Vestbo; J.M. Vonk; J Yim; Mika Kähönen; Terho Lehtimäki

doi:10.1038/s41588-018-0342-2

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

P. Sakornsakolpat, D. Prokopenko, M. Lamontagne, N.F. Reeve, A.L. Guyatt, V.E. Jackson, N. Shrine, D. Qiao, T.M. Bartz, D.K. Kim, M.K. Lee, J.C. Latourelle, X. Li, J.D. Morrow, M. Obeidat, A.B. Wyss, P. Bakke, R.G. Barr, T.H. Beaty, S.A. BelinskyG.G. Brusselle, J.D. Crapo, K. de Jong, D.L. DeMeo, T.E. Fingerlin, S.A. Gharib, A. Gulsvik, I.P. Hall, J.E. Hokanson, W.J. Kim, D.A. Lomas, S.J. London, D.A. Meyers, G.T. O'Connor, S.I. Rennard, D.A. Schwartz, P. Sliwinski, D. Sparrow, D.P. Strachan, R. Tal-Singer, Y. Tesfaigzi, J. Vestbo, J.M. Vonk, J Yim, Mika Kähönen, Terho Lehtimäki

Department of Clinical Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

209 Citations (Scopus)

Original language	English
Pages (from-to)	494-505
Journal	Nature Genetics
Volume	51
Issue number	3
DOIs	https://doi.org/10.1038/s41588-018-0342-2
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

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Publication forum level 3

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10.1038/s41588-018-0342-2

Cite this

Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H., ... Lehtimäki, T. (2019). Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nature Genetics, 51(3), 494-505. https://doi.org/10.1038/s41588-018-0342-2

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title = "Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations",

author = "P. Sakornsakolpat and D. Prokopenko and M. Lamontagne and N.F. Reeve and A.L. Guyatt and V.E. Jackson and N. Shrine and D. Qiao and T.M. Bartz and D.K. Kim and M.K. Lee and J.C. Latourelle and X. Li and J.D. Morrow and M. Obeidat and A.B. Wyss and P. Bakke and R.G. Barr and T.H. Beaty and S.A. Belinsky and G.G. Brusselle and J.D. Crapo and {de Jong}, K. and D.L. DeMeo and T.E. Fingerlin and S.A. Gharib and A. Gulsvik and I.P. Hall and J.E. Hokanson and W.J. Kim and D.A. Lomas and S.J. London and D.A. Meyers and G.T. O'Connor and S.I. Rennard and D.A. Schwartz and P. Sliwinski and D. Sparrow and D.P. Strachan and R. Tal-Singer and Y. Tesfaigzi and J. Vestbo and J.M. Vonk and J Yim and Mika K{\"a}h{\"o}nen and Terho Lehtim{\"a}ki",

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doi = "10.1038/s41588-018-0342-2",

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Sakornsakolpat, P, Prokopenko, D, Lamontagne, M, Reeve, NF, Guyatt, AL, Jackson, VE, Shrine, N, Qiao, D, Bartz, TM, Kim, DK, Lee, MK, Latourelle, JC, Li, X, Morrow, JD, Obeidat, M, Wyss, AB, Bakke, P, Barr, RG, Beaty, TH, Belinsky, SA, Brusselle, GG, Crapo, JD, de Jong, K, DeMeo, DL, Fingerlin, TE, Gharib, SA, Gulsvik, A, Hall, IP, Hokanson, JE, Kim, WJ, Lomas, DA, London, SJ, Meyers, DA, O'Connor, GT, Rennard, SI, Schwartz, DA, Sliwinski, P, Sparrow, D, Strachan, DP, Tal-Singer, R, Tesfaigzi, Y, Vestbo, J, Vonk, JM, Yim, J, Kähönen, M & Lehtimäki, T 2019, 'Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations', Nature Genetics, vol. 51, no. 3, pp. 494-505. https://doi.org/10.1038/s41588-018-0342-2

TY - JOUR

T1 - Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

AU - Sakornsakolpat, P.

AU - Prokopenko, D.

AU - Lamontagne, M.

AU - Reeve, N.F.

AU - Guyatt, A.L.

AU - Jackson, V.E.

AU - Shrine, N.

AU - Qiao, D.

AU - Bartz, T.M.

AU - Kim, D.K.

AU - Lee, M.K.

AU - Latourelle, J.C.

AU - Li, X.

AU - Morrow, J.D.

AU - Obeidat, M.

AU - Wyss, A.B.

AU - Bakke, P.

AU - Barr, R.G.

AU - Beaty, T.H.

AU - Belinsky, S.A.

AU - Brusselle, G.G.

AU - Crapo, J.D.

AU - de Jong, K.

AU - DeMeo, D.L.

AU - Fingerlin, T.E.

AU - Gharib, S.A.

AU - Gulsvik, A.

AU - Hall, I.P.

AU - Hokanson, J.E.

AU - Kim, W.J.

AU - Lomas, D.A.

AU - London, S.J.

AU - Meyers, D.A.

AU - O'Connor, G.T.

AU - Rennard, S.I.

AU - Schwartz, D.A.

AU - Sliwinski, P.

AU - Sparrow, D.

AU - Strachan, D.P.

AU - Tal-Singer, R.

AU - Tesfaigzi, Y.

AU - Vestbo, J.

AU - Vonk, J.M.

AU - Yim, J

AU - Kähönen, Mika

AU - Lehtimäki, Terho

PY - 2019

Y1 - 2019

U2 - 10.1038/s41588-018-0342-2

DO - 10.1038/s41588-018-0342-2

M3 - Article

SN - 1061-4036

VL - 51

SP - 494

EP - 505

JO - Nature Genetics

JF - Nature Genetics

IS - 3

ER -