Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Linnér R. Karlsson; P. Biroli; E. Kong; S.F.W. Meddens; R. Wedow; M.A. Fontana; I Seppälä; M. Lebreton; S.P. Tino; A. Abdellaoui; A.R. Hammerschlag; M.G. Nivard; A. Okbay; C.A. Rietveld; P.N. Timshel; M. Trzaskowski; R. Vlaming; C.L. Zünd; Y. Bao; L. Buzdugan; A.H. Caplin; C.-Y. Chen; P. Eibich; P. Fontanillas; J.R. Gonzalez; P.K. Joshi; V. Karhunen; A. Kleinman; R.Z. Levin; C.M. Lill; G.A. Meddens; G. Muntané; S. Sanchez-Roige; F.J. Rooij; E. Taskesen; Y. Wu; F. Zhang; M. Agee; B. Alipanahi; R.K. Bell; K. Bryc; S.L. Elson; N.A. Furlotte; K.E. Huber; Mika Kähönen; Terho Lehtimäki

doi:10.1038/s41588-018-0309-3

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Linnér R. Karlsson, P. Biroli, E. Kong, S.F.W. Meddens, R. Wedow, M.A. Fontana, I Seppälä, M. Lebreton, S.P. Tino, A. Abdellaoui, A.R. Hammerschlag, M.G. Nivard, A. Okbay, C.A. Rietveld, P.N. Timshel, M. Trzaskowski, R. Vlaming, C.L. Zünd, Y. Bao, L. BuzduganA.H. Caplin, C.-Y. Chen, P. Eibich, P. Fontanillas, J.R. Gonzalez, P.K. Joshi, V. Karhunen, A. Kleinman, R.Z. Levin, C.M. Lill, G.A. Meddens, G. Muntané, S. Sanchez-Roige, F.J. Rooij, E. Taskesen, Y. Wu, F. Zhang, M. Agee, B. Alipanahi, R.K. Bell, K. Bryc, S.L. Elson, N.A. Furlotte, K.E. Huber, Mika Kähönen, Terho Lehtimäki

Department of Clinical Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

385 Citations (Scopus)

Original language	English
Pages (from-to)	245-257
Journal	Nature Genetics
Volume	51
Issue number	2
DOIs	https://doi.org/10.1038/s41588-018-0309-3
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

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Publication forum level 3

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10.1038/s41588-018-0309-3

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Karlsson, L. R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Seppälä, I., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R., Zünd, C. L., Bao, Y., ... Lehtimäki, T. (2019). Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics, 51(2), 245-257. https://doi.org/10.1038/s41588-018-0309-3

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title = "Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences",

author = "Karlsson, {Linn{\'e}r R.} and P. Biroli and E. Kong and S.F.W. Meddens and R. Wedow and M.A. Fontana and I Sepp{\"a}l{\"a} and M. Lebreton and S.P. Tino and A. Abdellaoui and A.R. Hammerschlag and M.G. Nivard and A. Okbay and C.A. Rietveld and P.N. Timshel and M. Trzaskowski and R. Vlaming and C.L. Z{\"u}nd and Y. Bao and L. Buzdugan and A.H. Caplin and C.-Y. Chen and P. Eibich and P. Fontanillas and J.R. Gonzalez and P.K. Joshi and V. Karhunen and A. Kleinman and R.Z. Levin and C.M. Lill and G.A. Meddens and G. Muntan{\'e} and S. Sanchez-Roige and F.J. Rooij and E. Taskesen and Y. Wu and F. Zhang and M. Agee and B. Alipanahi and R.K. Bell and K. Bryc and S.L. Elson and N.A. Furlotte and K.E. Huber and Mika K{\"a}h{\"o}nen and Terho Lehtim{\"a}ki",

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doi = "10.1038/s41588-018-0309-3",

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volume = "51",

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Karlsson, LR, Biroli, P, Kong, E, Meddens, SFW, Wedow, R, Fontana, MA, Seppälä, I, Lebreton, M, Tino, SP, Abdellaoui, A, Hammerschlag, AR, Nivard, MG, Okbay, A, Rietveld, CA, Timshel, PN, Trzaskowski, M, Vlaming, R, Zünd, CL, Bao, Y, Buzdugan, L, Caplin, AH, Chen, C-Y, Eibich, P, Fontanillas, P, Gonzalez, JR, Joshi, PK, Karhunen, V, Kleinman, A, Levin, RZ, Lill, CM, Meddens, GA, Muntané, G, Sanchez-Roige, S, Rooij, FJ, Taskesen, E, Wu, Y, Zhang, F, Agee, M, Alipanahi, B, Bell, RK, Bryc, K, Elson, SL, Furlotte, NA, Huber, KE, Kähönen, M & Lehtimäki, T 2019, 'Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences', Nature Genetics, vol. 51, no. 2, pp. 245-257. https://doi.org/10.1038/s41588-018-0309-3

TY - JOUR

T1 - Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

AU - Karlsson, Linnér R.

AU - Biroli, P.

AU - Kong, E.

AU - Meddens, S.F.W.

AU - Wedow, R.

AU - Fontana, M.A.

AU - Seppälä, I

AU - Lebreton, M.

AU - Tino, S.P.

AU - Abdellaoui, A.

AU - Hammerschlag, A.R.

AU - Nivard, M.G.

AU - Okbay, A.

AU - Rietveld, C.A.

AU - Timshel, P.N.

AU - Trzaskowski, M.

AU - Vlaming, R.

AU - Zünd, C.L.

AU - Bao, Y.

AU - Buzdugan, L.

AU - Caplin, A.H.

AU - Chen, C.-Y.

AU - Eibich, P.

AU - Fontanillas, P.

AU - Gonzalez, J.R.

AU - Joshi, P.K.

AU - Karhunen, V.

AU - Kleinman, A.

AU - Levin, R.Z.

AU - Lill, C.M.

AU - Meddens, G.A.

AU - Muntané, G.

AU - Sanchez-Roige, S.

AU - Rooij, F.J.

AU - Taskesen, E.

AU - Wu, Y.

AU - Zhang, F.

AU - Agee, M.

AU - Alipanahi, B.

AU - Bell, R.K.

AU - Bryc, K.

AU - Elson, S.L.

AU - Furlotte, N.A.

AU - Huber, K.E.

AU - Kähönen, Mika

AU - Lehtimäki, Terho

PY - 2019

Y1 - 2019

U2 - 10.1038/s41588-018-0309-3

DO - 10.1038/s41588-018-0309-3

M3 - Article

SN - 1061-4036

VL - 51

SP - 245

EP - 257

JO - Nature Genetics

JF - Nature Genetics

IS - 2

ER -