Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Helen R. Warren; Evangelos Evangelou; Claudia P. Cabrera; He Gao; Meixia Ren; Borbala Mifsud; Ioanna Ntalla; Praveen Surendran; Chunyu Liu; James P. Cook; Aldi T. Kraja; Fotios Drenos; Marie Loh; Niek Verweij; Jonathan Marten; Ibrahim Karaman; Marcelo P. Segura Lepe; Paul F. O'Reilly; Joanne Knight; Harold Snieder; Norihiro Kato; Jiang He; E. Shyong Tai; M. Abdullah Said; David Porteous; Maris Alver; Neil Poulter; Martin Farrall; Ron T. Gansevoort; Sandosh Padmanabhan; Reedik Magi; Alice Stanton; John Connell; Stephan J. L. Bakker; Andres Metspalu; D Shields; Mika Kähönen; Terho Lehtimäki; Leo-Pekka Lyytikäinen

doi:10.1038/ng.3768

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Helen R. Warren, Evangelos Evangelou, Claudia P. Cabrera, He Gao, Meixia Ren, Borbala Mifsud, Ioanna Ntalla, Praveen Surendran, Chunyu Liu, James P. Cook, Aldi T. Kraja, Fotios Drenos, Marie Loh, Niek Verweij, Jonathan Marten, Ibrahim Karaman, Marcelo P. Segura Lepe, Paul F. O'Reilly, Joanne Knight, Harold SniederNorihiro Kato, Jiang He, E. Shyong Tai, M. Abdullah Said, David Porteous, Maris Alver, Neil Poulter, Martin Farrall, Ron T. Gansevoort, Sandosh Padmanabhan, Reedik Magi, Alice Stanton, John Connell, Stephan J. L. Bakker, Andres Metspalu, D Shields, Mika Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen

Department of Clinical Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

402 Citations (Scopus)

Original language	English
Pages (from-to)	403-415
Journal	Nature Genetics
Volume	49
Issue number	3
DOIs	https://doi.org/10.1038/ng.3768
Publication status	Published - 2017
Publication type	A1 Journal article-refereed

Keywords

Genome-wide association studies
Hypertension

Publication forum classification

Publication forum level 3

Access to Document

10.1038/ng.3768

Cite this

Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Segura Lepe, M. P., O'Reilly, P. F., Knight, J., ... Lyytikäinen, L.-P. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 49(3), 403-415. https://doi.org/10.1038/ng.3768

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title = "Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk",

keywords = "Genome-wide association studies, Hypertension, Genome-wide association studies, Hypertension",

author = "Warren, {Helen R.} and Evangelos Evangelou and Cabrera, {Claudia P.} and He Gao and Meixia Ren and Borbala Mifsud and Ioanna Ntalla and Praveen Surendran and Chunyu Liu and Cook, {James P.} and Kraja, {Aldi T.} and Fotios Drenos and Marie Loh and Niek Verweij and Jonathan Marten and Ibrahim Karaman and {Segura Lepe}, {Marcelo P.} and O'Reilly, {Paul F.} and Joanne Knight and Harold Snieder and Norihiro Kato and Jiang He and Tai, {E. Shyong} and Said, {M. Abdullah} and David Porteous and Maris Alver and Neil Poulter and Martin Farrall and Gansevoort, {Ron T.} and Sandosh Padmanabhan and Reedik Magi and Alice Stanton and John Connell and Bakker, {Stephan J. L.} and Andres Metspalu and D Shields and Mika K{\"a}h{\"o}nen and Terho Lehtim{\"a}ki and Leo-Pekka Lyytik{\"a}inen",

year = "2017",

doi = "10.1038/ng.3768",

language = "English",

volume = "49",

pages = "403--415",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "3",

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Warren, HR, Evangelou, E, Cabrera, CP, Gao, H, Ren, M, Mifsud, B, Ntalla, I, Surendran, P, Liu, C, Cook, JP, Kraja, AT, Drenos, F, Loh, M, Verweij, N, Marten, J, Karaman, I, Segura Lepe, MP, O'Reilly, PF, Knight, J, Snieder, H, Kato, N, He, J, Tai, ES, Said, MA, Porteous, D, Alver, M, Poulter, N, Farrall, M, Gansevoort, RT, Padmanabhan, S, Magi, R, Stanton, A, Connell, J, Bakker, SJL, Metspalu, A, Shields, D, Kähönen, M , Lehtimäki, T & Lyytikäinen, L-P 2017, 'Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk', Nature Genetics, vol. 49, no. 3, pp. 403-415. https://doi.org/10.1038/ng.3768

TY - JOUR

T1 - Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

AU - Warren, Helen R.

AU - Evangelou, Evangelos

AU - Cabrera, Claudia P.

AU - Gao, He

AU - Ren, Meixia

AU - Mifsud, Borbala

AU - Ntalla, Ioanna

AU - Surendran, Praveen

AU - Liu, Chunyu

AU - Cook, James P.

AU - Kraja, Aldi T.

AU - Drenos, Fotios

AU - Loh, Marie

AU - Verweij, Niek

AU - Marten, Jonathan

AU - Karaman, Ibrahim

AU - Segura Lepe, Marcelo P.

AU - O'Reilly, Paul F.

AU - Knight, Joanne

AU - Snieder, Harold

AU - Kato, Norihiro

AU - He, Jiang

AU - Tai, E. Shyong

AU - Said, M. Abdullah

AU - Porteous, David

AU - Alver, Maris

AU - Poulter, Neil

AU - Farrall, Martin

AU - Gansevoort, Ron T.

AU - Padmanabhan, Sandosh

AU - Magi, Reedik

AU - Stanton, Alice

AU - Connell, John

AU - Bakker, Stephan J. L.

AU - Metspalu, Andres

AU - Shields, D

AU - Kähönen, Mika

AU - Lehtimäki, Terho

AU - Lyytikäinen, Leo-Pekka

PY - 2017

Y1 - 2017

KW - Genome-wide association studies

KW - Hypertension

KW - Genome-wide association studies

KW - Hypertension

U2 - 10.1038/ng.3768

DO - 10.1038/ng.3768

M3 - Article

SN - 1061-4036

VL - 49

SP - 403

EP - 415

JO - Nature Genetics

JF - Nature Genetics

IS - 3

ER -