Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

P.R. Timmers; N. Mounier; K. Lall; K. Fischer; Z. Ning; X. Feng; A.D. Bretherick; D.W. Clark; M. Agbessi; H. Ahsan; I. Alves; A. Andiappan; P. Awadalla; A. Battle; M.J. Bonder; D. Boomsma; M. Christiansen; A. Claringbould; I Seppälä; P. Deelen; J. van Dongen; T. Esko; M. Favé; L. Franke; T. Frayling; S.A. Gharib; G. Gibson; G. Hemani; R. Jansen; A. Kalnapenkis; S. Kasela; J. Kettunen; Y. Kim; H. Kirsten; P. Kovacs; K. Krohn; J. Kronberg-Guzman; V. Kukushkina; Z. Kutalik; M. Kähönen; B. Lee; T. Lehtimäki; M. Loeffler; U. Marigorta; A Metspalu

doi:10.7554/elife.39856

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

P.R. Timmers, N. Mounier, K. Lall, K. Fischer, Z. Ning, X. Feng, A.D. Bretherick, D.W. Clark, M. Agbessi, H. Ahsan, I. Alves, A. Andiappan, P. Awadalla, A. Battle, M.J. Bonder, D. Boomsma, M. Christiansen, A. Claringbould, I Seppälä, P. DeelenJ. van Dongen, T. Esko, M. Favé, L. Franke, T. Frayling, S.A. Gharib, G. Gibson, G. Hemani, R. Jansen, A. Kalnapenkis, S. Kasela, J. Kettunen, Y. Kim, H. Kirsten, P. Kovacs, K. Krohn, J. Kronberg-Guzman, V. Kukushkina, Z. Kutalik, M. Kähönen, B. Lee, T. Lehtimäki, M. Loeffler, U. Marigorta, A Metspalu

Research output: Contribution to journal › Article › Scientific › peer-review

48 Citations (Scopus)

Original language	English
Article number	e39856
Pages (from-to)	e39856
Journal	eLIFE
Volume	8
DOIs	https://doi.org/10.7554/elife.39856
Publication status	Published - 2019
Publication type	A1 Journal article-refereed

Keywords

complex trait
genetics
genomics
human
lifespan
longevity

Publication forum classification

Publication forum level 2

Access to Document

10.7554/elife.39856

http://urn.fi/urn:nbn:fi:tuni-201907012367

Cite this

Timmers, P. R., Mounier, N., Lall, K., Fischer, K., Ning, Z., Feng, X., Bretherick, A. D., Clark, D. W., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Awadalla, P., Battle, A., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Seppälä, I., ... Metspalu, A. (2019). Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. eLIFE, 8, e39856. [e39856]. https://doi.org/10.7554/elife.39856

Timmers, P.R. ; Mounier, N. ; Lall, K. ; Fischer, K. ; Ning, Z. ; Feng, X. ; Bretherick, A.D. ; Clark, D.W. ; Agbessi, M. ; Ahsan, H. ; Alves, I. ; Andiappan, A. ; Awadalla, P. ; Battle, A. ; Bonder, M.J. ; Boomsma, D. ; Christiansen, M. ; Claringbould, A. ; Seppälä, I ; Deelen, P. ; van Dongen, J. ; Esko, T. ; Favé, M. ; Franke, L. ; Frayling, T. ; Gharib, S.A. ; Gibson, G. ; Hemani, G. ; Jansen, R. ; Kalnapenkis, A. ; Kasela, S. ; Kettunen, J. ; Kim, Y. ; Kirsten, H. ; Kovacs, P. ; Krohn, K. ; Kronberg-Guzman, J. ; Kukushkina, V. ; Kutalik, Z. ; Kähönen, M. ; Lee, B. ; Lehtimäki, T. ; Loeffler, M. ; Marigorta, U. ; Metspalu, A. / Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. In: eLIFE. 2019 ; Vol. 8. pp. e39856.

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title = "Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances",

keywords = "complex trait, genetics, genomics, human, lifespan, longevity, complex trait, genetics, genomics, human, lifespan, longevity",

author = "P.R. Timmers and N. Mounier and K. Lall and K. Fischer and Z. Ning and X. Feng and A.D. Bretherick and D.W. Clark and M. Agbessi and H. Ahsan and I. Alves and A. Andiappan and P. Awadalla and A. Battle and M.J. Bonder and D. Boomsma and M. Christiansen and A. Claringbould and I Sepp{\"a}l{\"a} and P. Deelen and {van Dongen}, J. and T. Esko and M. Fav{\'e} and L. Franke and T. Frayling and S.A. Gharib and G. Gibson and G. Hemani and R. Jansen and A. Kalnapenkis and S. Kasela and J. Kettunen and Y. Kim and H. Kirsten and P. Kovacs and K. Krohn and J. Kronberg-Guzman and V. Kukushkina and Z. Kutalik and M. K{\"a}h{\"o}nen and B. Lee and T. Lehtim{\"a}ki and M. Loeffler and U. Marigorta and A Metspalu",

year = "2019",

doi = "10.7554/elife.39856",

language = "English",

volume = "8",

pages = "e39856",

journal = "eLIFE",

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Timmers, PR, Mounier, N, Lall, K, Fischer, K, Ning, Z, Feng, X, Bretherick, AD, Clark, DW, Agbessi, M, Ahsan, H, Alves, I, Andiappan, A, Awadalla, P, Battle, A, Bonder, MJ, Boomsma, D, Christiansen, M, Claringbould, A, Seppälä, I, Deelen, P, van Dongen, J, Esko, T, Favé, M, Franke, L, Frayling, T, Gharib, SA, Gibson, G, Hemani, G, Jansen, R, Kalnapenkis, A, Kasela, S, Kettunen, J, Kim, Y, Kirsten, H, Kovacs, P, Krohn, K, Kronberg-Guzman, J, Kukushkina, V, Kutalik, Z, Kähönen, M, Lee, B, Lehtimäki, T, Loeffler, M, Marigorta, U & Metspalu, A 2019, 'Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances', eLIFE, vol. 8, e39856, pp. e39856. https://doi.org/10.7554/elife.39856

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. / Timmers, P.R.; Mounier, N.; Lall, K.; Fischer, K.; Ning, Z.; Feng, X.; Bretherick, A.D.; Clark, D.W.; Agbessi, M.; Ahsan, H.; Alves, I.; Andiappan, A.; Awadalla, P.; Battle, A.; Bonder, M.J.; Boomsma, D.; Christiansen, M.; Claringbould, A.; Seppälä, I; Deelen, P.; van Dongen, J.; Esko, T.; Favé, M.; Franke, L.; Frayling, T.; Gharib, S.A.; Gibson, G.; Hemani, G.; Jansen, R.; Kalnapenkis, A.; Kasela, S.; Kettunen, J.; Kim, Y.; Kirsten, H.; Kovacs, P.; Krohn, K.; Kronberg-Guzman, J.; Kukushkina, V.; Kutalik, Z.; Kähönen, M.; Lee, B.; Lehtimäki, T.; Loeffler, M.; Marigorta, U.; Metspalu, A.

In: eLIFE, Vol. 8, e39856, 2019, p. e39856.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

AU - Timmers, P.R.

AU - Mounier, N.

AU - Lall, K.

AU - Fischer, K.

AU - Ning, Z.

AU - Feng, X.

AU - Bretherick, A.D.

AU - Clark, D.W.

AU - Agbessi, M.

AU - Ahsan, H.

AU - Alves, I.

AU - Andiappan, A.

AU - Awadalla, P.

AU - Battle, A.

AU - Bonder, M.J.

AU - Boomsma, D.

AU - Christiansen, M.

AU - Claringbould, A.

AU - Seppälä, I

AU - Deelen, P.

AU - van Dongen, J.

AU - Esko, T.

AU - Favé, M.

AU - Franke, L.

AU - Frayling, T.

AU - Gharib, S.A.

AU - Gibson, G.

AU - Hemani, G.

AU - Jansen, R.

AU - Kalnapenkis, A.

AU - Kasela, S.

AU - Kettunen, J.

AU - Kim, Y.

AU - Kirsten, H.

AU - Kovacs, P.

AU - Krohn, K.

AU - Kronberg-Guzman, J.

AU - Kukushkina, V.

AU - Kutalik, Z.

AU - Kähönen, M.

AU - Lee, B.

AU - Lehtimäki, T.

AU - Loeffler, M.

AU - Marigorta, U.

AU - Metspalu, A

PY - 2019

Y1 - 2019

KW - complex trait

KW - genetics

KW - genomics

KW - human

KW - lifespan

KW - longevity

KW - complex trait

KW - genetics

KW - genomics

KW - human

KW - lifespan

KW - longevity

U2 - 10.7554/elife.39856

DO - 10.7554/elife.39856

M3 - Article

VL - 8

SP - e39856

JO - eLIFE

JF - eLIFE

SN - 2050-084X

M1 - e39856

ER -