Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions

Kamalakar P. Nandre; Jagdish K. Salunke; Jitendra P. Nandre; Vijay S. Patil; Amul U. Borse; Sidhanath V. Bhosale

doi:10.1016/j.cclet.2011.11.019

Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions

Kamalakar P. Nandre
, Jagdish K. Salunke
, Jitendra P. Nandre
, Vijay S. Patil
, Amul U. Borse
, Sidhanath V. Bhosale^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

26 Citations (Scopus)

Abstract

We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).

Original language	English
Pages (from-to)	161-164
Number of pages	4
Journal	Chinese Chemical Letters
Volume	23
Issue number	2
DOIs	https://doi.org/10.1016/j.cclet.2011.11.019
Publication status	Published - Feb 2012
Externally published	Yes
Publication type	A1 Journal article-refereed

Keywords

5-Substituted 1H-tetrazole
[3+2] Cycloaddition
Catalyst free
Glycerol
Nitriles

ASJC Scopus subject areas

General Chemistry

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10.1016/j.cclet.2011.11.019

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title = "Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions",

abstract = "We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95\%).",

keywords = "5-Substituted 1H-tetrazole, [3+2] Cycloaddition, Catalyst free, Glycerol, Nitriles",

author = "Nandre, \{Kamalakar P.\} and Salunke, \{Jagdish K.\} and Nandre, \{Jitendra P.\} and Patil, \{Vijay S.\} and Borse, \{Amul U.\} and Bhosale, \{Sidhanath V.\}",

note = "EXT={"}Salunke, Jagadish{"}",

year = "2012",

month = feb,

doi = "10.1016/j.cclet.2011.11.019",

language = "English",

volume = "23",

pages = "161--164",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions

AU - Nandre, Kamalakar P.

AU - Salunke, Jagdish K.

AU - Nandre, Jitendra P.

AU - Patil, Vijay S.

AU - Borse, Amul U.

AU - Bhosale, Sidhanath V.

N1 - EXT="Salunke, Jagadish"

PY - 2012/2

Y1 - 2012/2

N2 - We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).

AB - We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).

KW - 5-Substituted 1H-tetrazole

KW - [3+2] Cycloaddition

KW - Catalyst free

KW - Glycerol

KW - Nitriles

U2 - 10.1016/j.cclet.2011.11.019

DO - 10.1016/j.cclet.2011.11.019

M3 - Article

AN - SCOPUS:84855928133

SN - 1001-8417

VL - 23

SP - 161

EP - 164

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 2

ER -

Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions

Abstract

Keywords

ASJC Scopus subject areas

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