High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

E. Närvä; Reija Autio; N. Rahkonen; Lingjia Kong; N. Harrison; D. Kitsberg; L. Borghese; J. Itskovitz-Eldor; O. Rassool; P. Dvorak; O. Hovatta; T. Otonkoski; T. Tuuri; W. Cui; O. Brüstle; D. Baker; E. Maltby; H.D. Moore; N. Benvenisty; P.W. Andrews; Olli Yli-Harja; R. Lahesmaa

doi:10.1038/nbt.1615

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

E. Närvä, Reija Autio, N. Rahkonen, Lingjia Kong, N. Harrison, D. Kitsberg, L. Borghese, J. Itskovitz-Eldor, O. Rassool, P. Dvorak, O. Hovatta, T. Otonkoski, T. Tuuri, W. Cui, O. Brüstle, D. Baker, E. Maltby, H.D. Moore, N. Benvenisty, P.W. AndrewsOlli Yli-Harja, R. Lahesmaa

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Translated title of the contribution	High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity
Original language	English
Pages (from-to)	371-377
Journal	Nature Biotechnology
Volume	28
Issue number	4
DOIs	https://doi.org/10.1038/nbt.1615
Publication status	Published - 2010
Publication type	A1 Journal article-refereed

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Publication forum level 3

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10.1038/nbt.1615

Cite this

Närvä, E., Autio, R., Rahkonen, N., Kong, L., Harrison, N., Kitsberg, D., Borghese, L., Itskovitz-Eldor, J., Rassool, O., Dvorak, P., Hovatta, O., Otonkoski, T., Tuuri, T., Cui, W., Brüstle, O., Baker, D., Maltby, E., Moore, H. D., Benvenisty, N., ... Lahesmaa, R. (2010). High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nature Biotechnology, 28(4), 371-377. https://doi.org/10.1038/nbt.1615

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Närvä, E, Autio, R, Rahkonen, N, Kong, L, Harrison, N, Kitsberg, D, Borghese, L, Itskovitz-Eldor, J, Rassool, O, Dvorak, P, Hovatta, O, Otonkoski, T, Tuuri, T, Cui, W, Brüstle, O, Baker, D, Maltby, E, Moore, HD, Benvenisty, N, Andrews, PW, Yli-Harja, O & Lahesmaa, R 2010, 'High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity', Nature Biotechnology, vol. 28, no. 4, pp. 371-377. https://doi.org/10.1038/nbt.1615

TY - JOUR

T1 - High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

AU - Närvä, E.

AU - Autio, Reija

AU - Rahkonen, N.

AU - Kong, Lingjia

AU - Harrison, N.

AU - Kitsberg, D.

AU - Borghese, L.

AU - Itskovitz-Eldor, J.

AU - Rassool, O.

AU - Dvorak, P.

AU - Hovatta, O.

AU - Otonkoski, T.

AU - Tuuri, T.

AU - Cui, W.

AU - Brüstle, O.

AU - Baker, D.

AU - Maltby, E.

AU - Moore, H.D.

AU - Benvenisty, N.

AU - Andrews, P.W.

AU - Yli-Harja, Olli

AU - Lahesmaa, R.

N1 - Contribution: organisation=sgn,FACT1=1

PY - 2010

Y1 - 2010

U2 - 10.1038/nbt.1615

DO - 10.1038/nbt.1615

M3 - Article

SN - 1087-0156

VL - 28

SP - 371

EP - 377

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 4

ER -