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Human Pluripotent Stem Cell-Derived Neurons to Model Epilepsy
Ropafadzo Mzezewa
Biomedical Technology
Research output
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Book/Report
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Keyphrases
Seizure
100%
Human Pluripotent Stem Cells (hPSCs)
100%
Stem Cell-derived Neurons
100%
Epilepsy
100%
Seizure-like Activity
83%
Kainic Acid
66%
Neuronal Network
50%
Stem Cell-derived
50%
Interleukin-6
50%
Functional Level
33%
Microphysiological Platforms
33%
Dravet Syndrome
33%
On-a-chip
16%
Patient-specific
16%
Genetic Modification
16%
Level Change
16%
Active Role
16%
Multi-connectivity
16%
Neuronal Cells
16%
Insults
16%
Behavioral Activity
16%
Network Level
16%
Induced Pluripotent Stem Cells (iPSCs)
16%
Patient-derived
16%
Acid Activation
16%
Functional Development
16%
Physiologically Relevant
16%
Metabolic Alterations
16%
Neuronal Activity
16%
Mimicry
16%
Specific Receptor
16%
Specific Difference
16%
Inflammation
16%
All Ages
16%
Glutamate
16%
Genotype-phenotype
16%
Genotype-phenotype Correlation
16%
Structural Alterations
16%
Genetic Background
16%
Neurological Disorders
16%
Inducing Agents
16%
Symptom Relief
16%
Model in Vitro
16%
Interconnected Networks
16%
Human-based
16%
Genetic Constructs
16%
Seizure Models
16%
Seizure Type
16%
Clinical State
16%
Focal Seizures
16%
Pharmaceutical Research
16%
Clinical Model
16%
Antiseizure Medication
16%
Interleukin-6 Receptor (IL-6R)
16%
Immunological Changes
16%
Inflammatory Mediators
16%
Acid Induction
16%
Following Response
16%
GABAergic
16%
Human-specific
16%
Human Brain Connectivity
16%
Epilepsy Research
16%
Functional Behavior
16%
Neuroscience
Stem Cell
100%
Kainic Acid
80%
Interleukin 6
60%
Behavior (Neuroscience)
40%
Dravet Syndrome
40%
In Vitro
20%
Neuronal Activity
20%
Gamma-Aminobutyric Acid
20%
Glutamic Acid
20%
Gene Mutation
20%
Nervous System Disorder
20%
Seizure Types
20%
Antiseizure Medication
20%
Anti-Seizure Medication
20%
Receptor
20%