TY - JOUR
T1 - Impulsivity as a predictor of newly-diagnosed peptic ulcer disease
T2 - A prospective cohort study
AU - Granö, Niklas
AU - Puttonen, Sampsa
AU - Elovainio, Marko
AU - Virtanen, Marianna
AU - Väänänen, Ari
AU - Vahtera, Jussi
AU - Keltikangas-Järvinen, Liisa
AU - Kivimäki, Mika
N1 - Funding Information:
This study was supported by grants from the Finnish Work Environment Fund and the Academy of Finland (Projects 104891 and 105195).
PY - 2006/12
Y1 - 2006/12
N2 - We examined the role of impulsivity in the development of peptic ulcer disease (PUD). The subjects were initially healthy 4636 hospital employees aged 19-62 who responded to a questionnaire on personality, health habits, mental health, and PUD in 1998 and 2000. We used multivariate logistic analyses to determine the relationship between impulsivity and newly-diagnosed PUD among those employees who did not have PUD at baseline. Impulsivity was assessed with the Karolinska Scale of Personality. High level of impulsivity was associated with increased 2-year incidence of doctor-diagnosed PUD after adjustment of age, gender, education and shift work (odds ratio = 2.42, 95% confidence interval = 1.21-4.82). Additional adjustment for the effects of smoking, alcohol consumption, BMI, physical activity, minor psychiatric morbidity and diagnosed depression and other psychiatric disease had little effect on this relationship. The present study suggests that impulsivity may be a risk factor for the development of PUD.
AB - We examined the role of impulsivity in the development of peptic ulcer disease (PUD). The subjects were initially healthy 4636 hospital employees aged 19-62 who responded to a questionnaire on personality, health habits, mental health, and PUD in 1998 and 2000. We used multivariate logistic analyses to determine the relationship between impulsivity and newly-diagnosed PUD among those employees who did not have PUD at baseline. Impulsivity was assessed with the Karolinska Scale of Personality. High level of impulsivity was associated with increased 2-year incidence of doctor-diagnosed PUD after adjustment of age, gender, education and shift work (odds ratio = 2.42, 95% confidence interval = 1.21-4.82). Additional adjustment for the effects of smoking, alcohol consumption, BMI, physical activity, minor psychiatric morbidity and diagnosed depression and other psychiatric disease had little effect on this relationship. The present study suggests that impulsivity may be a risk factor for the development of PUD.
KW - Follow-up study
KW - Impulsivity
KW - Incidence
KW - Peptic ulcer disease
KW - Psychosocial factors
U2 - 10.1016/j.paid.2006.04.026
DO - 10.1016/j.paid.2006.04.026
M3 - Article
AN - SCOPUS:33748689008
SN - 0191-8869
VL - 41
SP - 1539
EP - 1550
JO - PERSONALITY AND INDIVIDUAL DIFFERENCES
JF - PERSONALITY AND INDIVIDUAL DIFFERENCES
IS - 8
ER -
