In vitrostem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsbyfundusdystrophy

Heidi Hongisto, Hannu Uusitalo, Kai Kaarniranta, J. Arjuna Ratnayaka, Heli Skottman, Andrew J. Lotery, Jennifer M. Dewing, David R. G. Christensen, Jennifer Scott, Angela J. Cree, Janika Nättinen, Juha Määttä, Antti Jylhä, Ulla Aapola

Research output: Contribution to journalArticlepeer-review

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Original languageEnglish
Article numbere5506
Pages (from-to)138-150
Number of pages13
JournalJournal of Pathology
Issue number2
Publication statusPublished - 2020
Publication typeA1 Journal article-refereed


  • Sorsby fundus dystrophy
  • human induced pluripotent stem cell
  • metalloproteinase inhibitor 3
  • retinal degeneration
  • retinal pigment epithelial cell

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  • Publication forum level 2

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