Infant and Adult Inhalation Exposure to Resuspended Biological Particulate Matter

Tianren Wu, Martin Täubel, Rauno Holopainen, Anna-Kaisa Viitanen, Sinikka Vainiotalo, Timo Tuomi, Jorma Keskinen, Anne Hyvärinen, Kaarle Hämeri, Sampo E. Saari, Brandon E. Boor

    Research output: Contribution to journalArticleScientificpeer-review

    29 Citations (Scopus)

    Abstract

    Human-induced resuspension of floor dust is a dynamic process that can serve as a major indoor source of biological particulate matter (bioPM). Inhalation exposure to the microbial and allergenic content of indoor dust is associated with adverse and protective health effects. This study evaluates infant and adult inhalation exposures and respiratory tract deposited dose rates of resuspended bioPM from carpets. Chamber experiments were conducted with a robotic crawling infant and an adult performing a walking sequence. Breathing zone (BZ) size distributions of resuspended fluorescent biological aerosol particles (FBAPs), a bioPM proxy, were monitored in real-time. FBAP exposures were highly transient during periods of locomotion. Both crawling and walking delivered a significant number of resuspended FBAPs to the BZ, with concentrations ranging from 0.5 to 2 cm-3 (mass range: ∼50 to 600 μg/m3). Infants and adults are primarily exposed to a unimodal FBAP size distribution between 2 and 6 μm, with infants receiving greater exposures to super-10 μm FBAPs. In just 1 min of crawling or walking, 103-104 resuspended FBAPs can deposit in the respiratory tract, with an infant receiving much of their respiratory tract deposited dose in their lower airways. Per kg body mass, an infant will receive a nearly four times greater respiratory tract deposited dose of resuspended FBAPs compared to an adult.

    Original languageEnglish
    Pages (from-to)237-247
    Number of pages11
    JournalEnvironmental Science and Technology
    Volume52
    Issue number1
    Early online date16 Nov 2017
    DOIs
    Publication statusPublished - 2018
    Publication typeA1 Journal article-refereed

    Keywords

    • Journal Article

    Publication forum classification

    • Publication forum level 2

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