Inflammasomi - tulehdusreaktion keskeinen säätelijä

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3 Citations (Scopus)


The function of inflammasome in the cell is to sense intracellular danger signals and--perhaps as the last cry of distress of a cell invaded by a microorganism--at an emergency situation to release interleukins (IL) outside of the cell, causing an inflammatory reaction and fever and also leads to an elevation of CRP. In a hopeless situation inflammasome-regulated pyroptosis is started. Disturbed action of inflammasomes has been linked to the pathogenesis of various disorders such as gout, atherosclerosis, asbestosis and type 2 diabetes. As the pathogenetic mechanisms of such diseases become clear, improved treatments for them may also become available.

Original languageFinnish
Pages (from-to)705-711
Number of pages7
JournalLääketieteellinen Aikakauskirja Duodecim
Issue number7
Publication statusPublished - 2013
Publication typeA2 Review article in a scientific journal


  • auto-inflammatoriset taudit
  • auto-inflammatory diseases,
  • inflammasome
  • inflammasomi
  • inflammation
  • tulehdusreaktio

Publication forum classification

  • Publication forum level 1

ASJC Scopus subject areas

  • Medicine(all)

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