Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study

Katri Korpela, Otto Helve, Kaija-Leena Kolho, Terhi Saisto, Kirsi Skogberg, Evgenia Dikareva, Vedran Stefanovic, Anne Salonen, Sture Andersson, Willem M. de Vos

Research output: Contribution to journalArticleScientificpeer-review

19 Citations (Scopus)

Abstract

A proof-of-concept safety study shows that oral fecal transplantation can shift the microbiome composition of infants who are born via cesarean section to a profile that is more similar to those born via vaginal delivery.

Original languageEnglish
Pages (from-to)324-334.e5
JournalCell
Volume183
Issue number2
DOIs
Publication statusPublished - 2020
Publication typeA1 Journal article-refereed

Keywords

  • cesarean section
  • clinical trial
  • colonization
  • early-life health
  • fecal microbiota transplantation
  • maternal seeding
  • microbiota development
  • newborn
  • selective outgrowth
  • vertical transmission

Publication forum classification

  • Publication forum level 3

Fingerprint

Dive into the research topics of 'Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study'. Together they form a unique fingerprint.

Cite this