Metabolic alterations in immune cells associate with progression to type 1 diabetes

Partho Sen; Riitta Veijola; Heikki Hyöty; Tuulia Hyötyläinen; Mikael Knip; Matej Oresic; Alex M. Dickens; María Asunción López-Bascón; Tuomas Lindeman; Esko Kemppainen; Santosh Lamichhane; Tuukka Rönkkö; Jorma Ilonen; Jorma Toppari

doi:10.1007/s00125-020-05107-6

Metabolic alterations in immune cells associate with progression to type 1 diabetes

Partho Sen
, Riitta Veijola
, Heikki Hyöty
, Tuulia Hyötyläinen
, Mikael Knip
, Matej Oresic
, Alex M. Dickens
, María Asunción López-Bascón
, Tuomas Lindeman
, Esko Kemppainen
, Santosh Lamichhane
, Tuukka Rönkkö
, Jorma Ilonen
, Jorma Toppari

Department of Clinical Microbiology

Research output: Contribution to journal › Article › Scientific › peer-review

49 Citations (Scopus)

Original language	English
Pages (from-to)	1017-1031
Journal	Diabetologia
Volume	63
Issue number	5
DOIs	https://doi.org/10.1007/s00125-020-05107-6
Publication status	Published - 2020
Publication type	A1 Journal article-refereed

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Birth cohort
Ceramides
Genome-scale metabolic modelling
Lipidomics
Metabolomics
Peripheral blood mononuclear cells
Sphingolipid metabolism
Type 1 diabetes

Publication forum classification

Publication forum level 2

Access to Document

10.1007/s00125-020-05107-6

http://urn.fi/URN:NBN:fi:tuni-202005275708

Cite this

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title = "Metabolic alterations in immune cells associate with progression to type 1 diabetes",

keywords = "Birth cohort, Ceramides, Genome-scale metabolic modelling, Lipidomics, Metabolomics, Peripheral blood mononuclear cells, Sphingolipid metabolism, Type 1 diabetes, Birth cohort, Ceramides, Genome-scale metabolic modelling, Lipidomics, Metabolomics, Peripheral blood mononuclear cells, Sphingolipid metabolism, Type 1 diabetes",

author = "Partho Sen and Riitta Veijola and Heikki Hy{\"o}ty and Tuulia Hy{\"o}tyl{\"a}inen and Mikael Knip and Matej Oresic and Dickens, \{Alex M.\} and L{\'o}pez-Basc{\'o}n, \{Mar{\'i}a Asunci{\'o}n\} and Tuomas Lindeman and Esko Kemppainen and Santosh Lamichhane and Tuukka R{\"o}nkk{\"o} and Jorma Ilonen and Jorma Toppari",

year = "2020",

doi = "10.1007/s00125-020-05107-6",

language = "English",

volume = "63",

pages = "1017--1031",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer",

number = "5",

}

TY - JOUR

T1 - Metabolic alterations in immune cells associate with progression to type 1 diabetes

AU - Sen, Partho

AU - Veijola, Riitta

AU - Hyöty, Heikki

AU - Hyötyläinen, Tuulia

AU - Knip, Mikael

AU - Oresic, Matej

AU - Dickens, Alex M.

AU - López-Bascón, María Asunción

AU - Lindeman, Tuomas

AU - Kemppainen, Esko

AU - Lamichhane, Santosh

AU - Rönkkö, Tuukka

AU - Ilonen, Jorma

AU - Toppari, Jorma

PY - 2020

Y1 - 2020

KW - Birth cohort

KW - Ceramides

KW - Genome-scale metabolic modelling

KW - Lipidomics

KW - Metabolomics

KW - Peripheral blood mononuclear cells

KW - Sphingolipid metabolism

KW - Type 1 diabetes

KW - Birth cohort

KW - Ceramides

KW - Genome-scale metabolic modelling

KW - Lipidomics

KW - Metabolomics

KW - Peripheral blood mononuclear cells

KW - Sphingolipid metabolism

KW - Type 1 diabetes

U2 - 10.1007/s00125-020-05107-6

DO - 10.1007/s00125-020-05107-6

M3 - Article

SN - 0012-186X

VL - 63

SP - 1017

EP - 1031

JO - Diabetologia

JF - Diabetologia

IS - 5

ER -